Structure and function of the large intestine Flashcards

1
Q

Name the four parts of the large intestine?

A

Ascending, descending, transverse, sigmoid

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2
Q

Which muscle of the large intestine is complete?

A

Circular muscle

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3
Q

Which muscle of the large intestine is incomplete?

A

Longitudinal muscle

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4
Q

What lies on the outside of the colon?

A

Teniae Coli

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5
Q

What happens when teniae coli contract?

A

They form haustra

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6
Q

What epithelium lines in the large intestine?

A

Simple Columnar

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7
Q

What do goblet cells produce?

A

Mucus

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8
Q

Why is mucus within the large intestine?

A

To aid with faeces movement

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9
Q

How is faeces formed?

A

Colon actively transports Na from lumen into blood -> osmotic absorption of water -> dehydration of chyme -> solid faecal pellets

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10
Q

Discuss the importance of intestinal bacteria in the digestive process?

A

Bacterial fermentation of undigested carbohydrates can occur in colon due to commensal bacteria –> short chain FA’s, Vit K and flatus

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11
Q

Describe the structure of the rectum

A

Straight muscular tube between end of sigmoid colon and anal canal

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12
Q

Describe the structure of the anal canal?

A

Tube between distal rectum and anus. Muscularis thicker than rectum to int. anal sphincter. Ext. anal sphincter is made up of skeletal muscle and the epithelium transitions from simple columnar to stratified squamous

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13
Q

Describe the defecation reflex

A

Contraction of rectum, relaxation of int. sphincter, contraction of external sphincter and increased peristalsis in colon. The ext. sphincter will then relax due to an increase in pressure which will cause faeces to expel themselves

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14
Q

What can cause secretory diarrhoea?

A

Pathogenic bacteria, protozoa, viruses, toxins, food and stress

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15
Q

Name the two enterotoxigenic bacteria which can cause secretory diarrhoea?

A

E-Coli, Vibrio Cholerae

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16
Q

What do enterotoxins do to the large intestines?

A

They maximally turn on intestine chloride secretion from crypt cells which increases H2O secretion. This swamps absorptive capacity if villus cells and profuse watery diarrhoea

17
Q

How do you treat cholera?

A

Sodium/glucose solution

18
Q

Why is a sodium/glucose solution effective?

A

Drives H2O Absorption which causes rehydration. The ongoing secretion will wash away infection