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Flashcards in Study Guide 1 Questions Deck (17)
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1

Late 1600s:

LIGHT MICROSCOPE (VISUALIZATION OF CELLS)
-Van Leeuwenhoek: Visualized organisms in pond water
-Robert Hooke: viewed dead cork

2

1800:

CELLS AND CELL THEORY
-Theordor Schwann--animal cells
-Matthias Schleiden--plant cells
-Rudolph Virchow--Cell Theory

3

Early 1900's:

GENETICS/BIOCHEMISTRY:
-Walter Sutton--enzymes
-Thomas Hunt Morgan--genetics
-Archibald gerrod--Genetic diseases
-Beadle and Tatum--one gene/one enzyme

4

1950-1970:

MOLECULAR BIOLOGY:
Watson & Crick deduced the structure of DNA, Leading to rapid advances in molecular biology

DNA to RNA to Protein

[ELECTRON MICROSCOPY]

5

~1970's:

BIOTECHNOLOGY:
-Isolation of Genes
-Gene Transfer
-PCR-Polymerase reaction

6

2000 and beyond:

Genomics
Proteomics
Imaging
High-ThroughPut

[CONFOCAL MICROSCOPY]

7

1970's:

Rise of recombinant DNA
-Isolating and cloning genes
-DNA sequencing

8

Provide 2 Examples of technical innovations that advanced the field of Cell Biology:

1-Watson & Crick deducing the structure of DNA

2-

9

Archibald Garrod:

-Associated human genetic Disease with biochemical defect

10

Beadle and Tatum:

-Used bread mold
-Screened for mutations in metabolism
-connected genes to enzymes
-Formulated One Gene = One Enzyme

11

Walter Sutton (Chromosomal theory of Inheritance):

Chromosomes are units of heredity
-He visualized chromosomes in dividing germ cells

12

Thomas Hunt Morgan (Chromosomal Theory of Inheritance)

-Initiated genetic model systems
Linked sex chromosomes to inheritance of particular chromosomes.

13

Prokaryotes:

(Eubacteria and Archea)
-Single celled organism
-No nucleus
-No membrane bound organelle
-DNA is circular and not complexed with protein.

14

Eukaryote:

-Single and multicellular
-Plants, animals, fungi
-Contains nucleus and membrane bound organelles
-DNA in form of Chromosomes

15

SIZE: Prokaryote Vs Eukaryote

-Eukaryotes are about 2X the size of a Prokaryote

-Eukaryotic cell (5-20 Micrometers/Microns)
-Prokaryotic cell ( 1-10 microns)

16

Animal Cell differ from plant cells by:

-No chloroplast
-No cell wall
-No central vacuole

17

Plant Cells differ from Animal cells:

-They HAVE chloroplasts
-HAVE a cell wall
-HAS a central Vacuole