Flashcards in Stuff We Got Wrong That One Time Deck (17):
Best approach to somatic symptom disorder
Increase regular scheduled visits with primary care provider
Histology of bone in Hyperparathyroidism
Subperiosteal resorption with cystic degeneration
Issue with Non-homologous end joining. Can see recurrent pulmonary infections, ataxia, nystagmus, superficial blanching nests of distended capillaries on sun exposed areas.
Class I anti-arrythmics affinity for receptor and quickest dissociations
Class IB has the lowest affinity, IA is second lowest, Class IC has the highest affinity (BAC)
Treatment for Severe SSRI overdose
Why does PaO2 drop slightly between Pulmonary capillaries and Left atrium?
Contribution to blood volume by returning bronchial veins before the Left atrium
Hyperacute allograft rejection
Due to preformed antibodies. See arterial fibrinoid necrosis and capillary thrombosis leading to gross molting and cyanosis
Club cells in lungs
Function in detoxification of lungs through P450 mechanism.
NO functions in autoregulation of...
Larger arteries and pre-arteriolar vessels
Adenosine functions in autoregulation of...
Small coronary arterioles
How fast to cardiac myocytes stop contracting during ischemia?
Within 1 minute. Will continue anaerobic glycolysis and not die for 30 minutes.
Place in vasculature with lowest oxygen content
Coronary sinus- Heart extracts the most O2 from the blood.
Process of Acid Fast Staining
Stain with carbolfuchsin, use HCl and alcohol to wash off stain, counterstain with methylene blue
Cord factor in mycobacterial species
Seen by growth of ropelike cords in serpantine pattern on microscopy. Cord factor is a mycoside, presence correlates with virulence of bug. Inactivates PMNs, damages mitochondria, causes release of TNF
5-FU mechanism of action
Binds THF and thymidylate synthetase in stable confirmation, thus making TS unavailable for thymidine synthesis. Leucorvin (formyl-THF) actually increases efficacy of 5-FU.
Observer effect. Tendency for study subjects to change behavior once they know they're being studied.