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Flashcards in Stuff We Got Wrong That One Time Deck (17):
1

Best approach to somatic symptom disorder

Increase regular scheduled visits with primary care provider

2

Histology of bone in Hyperparathyroidism

Subperiosteal resorption with cystic degeneration

3

Ataxia Telangiectasia

Issue with Non-homologous end joining. Can see recurrent pulmonary infections, ataxia, nystagmus, superficial blanching nests of distended capillaries on sun exposed areas.

4

Class I anti-arrythmics affinity for receptor and quickest dissociations

Class IB has the lowest affinity, IA is second lowest, Class IC has the highest affinity (BAC)

5

Treatment for Severe SSRI overdose

Cyproheptadine

6

Why does PaO2 drop slightly between Pulmonary capillaries and Left atrium?

Contribution to blood volume by returning bronchial veins before the Left atrium

7

Hyperacute allograft rejection

Due to preformed antibodies. See arterial fibrinoid necrosis and capillary thrombosis leading to gross molting and cyanosis

8

Club cells in lungs

Function in detoxification of lungs through P450 mechanism.

9

NO functions in autoregulation of...

Larger arteries and pre-arteriolar vessels

10

Adenosine functions in autoregulation of...

Small coronary arterioles

11

How fast to cardiac myocytes stop contracting during ischemia?

Within 1 minute. Will continue anaerobic glycolysis and not die for 30 minutes.

12

Place in vasculature with lowest oxygen content

Coronary sinus- Heart extracts the most O2 from the blood.

13

Process of Acid Fast Staining

Stain with carbolfuchsin, use HCl and alcohol to wash off stain, counterstain with methylene blue

14

Cord factor in mycobacterial species

Seen by growth of ropelike cords in serpantine pattern on microscopy. Cord factor is a mycoside, presence correlates with virulence of bug. Inactivates PMNs, damages mitochondria, causes release of TNF

15

5-FU mechanism of action

Binds THF and thymidylate synthetase in stable confirmation, thus making TS unavailable for thymidine synthesis. Leucorvin (formyl-THF) actually increases efficacy of 5-FU.

16

Hawthorne effect

Observer effect. Tendency for study subjects to change behavior once they know they're being studied.

17

Indication of severity of mitral stenosis

Earlier Opening snap = worse. Low A2-OS interval