Superficial Lesions Flashcards

(63 cards)

1
Q

lipoma

A

occurs anywhere fat can expand

Soft
Subcutaneous
Imprecise margin
Fluctuant

benign
saracomatous change v unlikley, if occurs likely old pt + in deeper tissues

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2
Q

sebaceous cyst

A

2 types - epidermal (from hair follicle infundibulum), trichilemmal (from hair follicle epithelium)

occurs anywhere hair grows
central punctum seen
Firm
Smooth
Intradermal

can get infected, calcified or ulcerate

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3
Q

ganglion

A

Cystic swelling related to a synovium lined structure e.g. joint, tendon
Contain thick, gelatinous material

90% on dorsum of hand or wrist
weakly transilluminable

Soft
Subcutaneous
May be tethered to tendon

DDx - consider bursae, arthritis sequelae

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4
Q

seborrhoeic keratosis

A

Benign hyperplasia of basal epithelial layer

  • Hyperkeratosis: keratin layer thickening
  • Acanthosis: stratum spinosum thickening

stuck on look, dark brown, greasy

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5
Q

neurofibroma

A

Benign nerve sheath tumour arising
from Schwann cells.

pedunculated, fleshy
pressure - pins/needles

must examine eyes / axilla / CNs if identified

may also see freckling, Lisch nodules in iris, cafe au lait spots

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6
Q

papilloma

A

skin tag

excision and diathermy if needed
bleed a lot as core is vascular

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7
Q

‘pyogenic granuloma’

A

rapidly growing fleshy red growth

remove trigger and excision / diathermy

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8
Q

dermoid cyst of skin

A

acquired or congenital

Smooth spherical swelling
Sites of embryological fusion

Soft
Non-tender
Subcutaneous

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9
Q

dermatofibroma

A
Can occur anywhere
Mostly on the lower limbs of young to
middle-aged women
Small, brown pigmented nodule
Firm, woody feel: characteristic
Intradermal: mobile over deep tissue

need biopsy as often unclear - exclude mal

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10
Q

keratoacanthoma

A

regress within six weeks
mild form of SCC
dome-shaped
remove

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11
Q

assessment malignant melanoma

A
Asymmetry
• Boarder: irregular
• Colour: non-uniform
• Diameter >6mm
• Evolving / Elevation
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12
Q

risk factors malignant melanoma

A
  • Sunlight: esp. intense exposure in early years.
  • Fair skinned (low Fitzpatrick skin type)
  • ↑ no. of common moles
  • +ve FH
  • ↑ age
  • Immunosuppression
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13
Q

5 types of malignant melanoma and some info for each

A
Superficial Spreading: 80%
§ Irregular boarders, colour variation
§ Commonest in Caucasians
§ Grow slowly, metastasise late = better
prognosis

• Lentigo Maligna Melanoma
§ Often elderly pts.
§ Face or scalp

• Acral Lentiginous
§ Asians/blacks
§ Palms, soles, subungual (Hutchinson’s sign)

• Nodular Melanoma
§ All sites
§ Younger age, new lesion
§ Invade deeply, metastasis early = poor prog

• Amelanotic
§ Atypical appearance → delayed Dx

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14
Q

staging melanoma

A
Breslow Depth
§ Thickness of tumour to deepest point of dermal
invasion
§ <1mm = >75% 5ys
§ >4mm = 50% 5ys

• Clark’s Staging
• Stratifies depth by 5 anatomical levels
§ Stage 1: Epidermis
§ Stage 5: s/c fat

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15
Q

management melanoma

A

excision incl secondary margin
+/- LN removal
+/- adjuvant chemotherapy

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16
Q

summarise SCC

A

Ulcerated lesion with hard, raised everted edges
• Sun exposed areas

Causes
• Sun exposure: scalp, face, ears, lower leg
• May arise in chronic ulcers: Marjolin’s Ulcer
• Xeroderma pigmentosa

Evolution
• Solar/actinic keratosis → Bowen’s → SCC
• Lymph node spread is rare

excise and radiotherapy locally if progressed

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17
Q

actinic keratosis

A
• Irregular, crusty warty lesions.
• Pre-malignant (~1%/yr)
Rx
• Cautery
• Cryo
• 5-FU
• Imiquimod
• Photodynamic phototherapy
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18
Q

Bowen’s disease

A
  • Red/brown scaly plaques
  • Typically on the legs of older women
  • SCC in situ

treat as actinic keratosis

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19
Q

basal cell carcinoma

A

• Commonest skin cancer
• Pearly nodule with rolled telangiectactic edge
• May ulcerate
• Typically on face in sun-exposed area
§ Above line from tragus → angle of mouth
Behaviour
• Low-grade malignancy → very rarely metastasise
• Locally invasive

treat with Mohs excision and cryotherapy

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20
Q

general info on neck lumps

A

• 85% of neck lumps are LNs: esp. if present <
3wks
§ Infection: EBV, tonsillitis, HIV
§ Ca: lymphoma or mets
• 8% are goitres
• 7% other: e.g. sebaceous cyst or lipoma

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21
Q

assessment of neck lumps in anterior triangle and DDx

A

Pulsatile
§ Carotid artery aneurysm
§ Tortuous carotid artery
§ Carotid body tumour (chemodectoma)

• Non-pulsatile
§ Branchial cysts
§ Laryngocele
§ Goitre
§ Parotid

triple asssess
exam, USS, FNA

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22
Q

neck lumps in submandibular area and DDx

A

Salivary stone
• Sialadenitis - inf
• Salivary tumour

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23
Q

causes of posterior triangle lumps

A
LNs
• Cervical ribs
• Pharyngeal pouch
• Cystic hygromas
• Pancoast’s tumour
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24
Q

cause of midline neck lumps

A
• <20yrs
§ Thyroglossal cyst
§ Dermoid cyst
• >20yrs
§ Thyroid isthmus mass
§ Ectopic thyroid tissue
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25
presentation and treatment branchial cysts
• Embryological remnant 2nd branchial cleft Presentation • Age <20yrs • Ant. margin of SCM at junction of upper and middle 3rd • May become infected → abscess abx if infected excise may form fistula
26
carotid body tumour - v rare, just FYI
``` Carotid Body Tumour: Chemodectoma • Very rare • Carotid bodies § Located @ carotid bifurcation § Detect pO2, pCO2 and H+ Presentation • Just anterior to upper 3rd of SCM. • Pulsatile • Move laterally but not vertically • May be bilateral • Pressure may → dizziness and syncope • Mostly benign (5% malignant) Ix: Doppler or angio: splaying of bifurcation Rx: extirpation by a vascular surgeon ```
27
laryngocoele
* Cystic dilatation of the laryngeal saccule * Congenital or acquired * Exacerbated by blowing may be seen in wind instrument players (rare)
28
define posterior and anterior triangle of the neck
divided by sternocleidomastoid QED
29
dermoid cyst
``` Developmental inclusion of epidermis along lines of skin fusion. Presentation • Common <20yrs • Found at junctions of embryological fusion § Neck midline § Lateral angles of eyebrow § Under tongue • Contains ectodermal elements § Hair follicles, sebaceous glands treat with excision ```
30
thyroglossal cyst
Cyst formed from persistent thyroglossal duct § Path of thyroid descent from base of tongue § Usually just inferior to the hyoid: subhyoid § Or, just above the hyoid: suprahyoid • Fluctuant lump that moves up on tongue protrusion • Can become infected → thyroglossal fistula treatment= • Sistrunk’s Op: excision of cyst and thyroglossal duct with segment of hyoid bone
31
cervical ribs general info
Overdevelopment of transverse process of C7 • Occur in 1:150 Presentation • Mostly asymptomatic • Hard swelling • ↓ radial pulse on abduction and external rotation of arm
32
cervical ribs complications
``` • Can → vascular symptoms § Compresses subclavian A § Raynaud’s § Subclavian steal § ↓ venous outflow → oedema ``` • Can → neurological symptoms § Compresses lower trunk of brachial plexus, T1 nerve root or stellate ganglion. § Wasting of intrinsic hand muscles § Paraesthesia along medial border of arm
33
pharyngeal pouch
``` Presentation • Swelling on left side of neck • Regurgitation and aspiration • Halitosis • Gurgling sounds • Food debris → pouch expansion → oesophageal compression → dysphagia. Ix: barium swallow Rx • Excision and cricopharyngeal myotomy • Endoscopic stapling ```
34
cystic hygroma
• Congenital multiloculated lymphangioma arising from the jugular lymph sac Presentation • Infants • Lower part of post. triangle but may extend to axilla. • ↑ in size when child coughs/cries • Transilluminates brilliantly Rx: excision or hypertonic saline sclerosant • May recur
35
full assessment of cervical lymphadenopathy
``` Key Features • Consistency • Number • Fixation • Symmetry • Tenderness ``` ``` Additional Examination • Face and scalp for infection or neoplasm • Chest exam: infection or neoplasm • Breast examination • Formal full ENT examination • Rest of reticuloendothelial system ``` ``` History • Symptoms from the lumps § E.g. EtOH-induced pain • General symptoms § Fever, malaise, wt. loss • Systemic disease § PMH § Previous operations • Social history § Ethnic origin § HIV risk factors ```
36
causes of cervical LNs raised
``` • Lymphoma and Leukaemia • Infection • Sarcoidosis • Tumours Infection • Bacterial § Tonsillitis, dental abscess § TB § Bartonella henselae (Cat-scratch disease) • Viral § EBV § HIV • Protozoal § Toxoplasmosis ```
37
investigations if concerned about cervical LNs
Blood • FBC, ESR, film (atypical lymphocytes) • TFTs, serum ACE • Monospot test, HIV test Radiological • US • CT scan Pathology • FNAC • Excision biopsy
38
define hypertrophic vs keloid scars
Hypertrophic • Scar confined to wound margins • Across flexor surfaces and skin creases • Appear soon after injury and regress spontaneously • Any age: commonly 8-20yrs • M=F • All races ``` Keloid • Scar extends beyond wound margins • Earlobes, chin, neck, shoulder, chest • Appear months after injury and continue to grow • Puberty to 30yrs • F>M • Black and Hispanic ```
39
managing keloid or hypertrophic scars
Non-surgical • Mechanical-pressure therapy • Topical silicone gel sheets • Intralesional steroid and LA injections Surgical • Revision of scar ¯c closure by direct suturing
40
summarise DDx structure for a goitre
diffuse multinodular solitary lump
41
diffuse goitre DDx
``` Diffuse • Simple colloid goitre § Endemic: iodine deficiency § Sporadic: autoimmune, hereditary, goitrogens (e.g. sulphonylureas) • Graves’ • Thyroiditis § Hashimoto’s § De Quervain’s § Subacute lymphocytic (e.g. post-partum) • (multinodular goitre ¯c nodules too small to palpate) ```
42
multinodular goitre DDx
Multinodular • Multinodular colloid goitre (commonest) • Multiple cysts • Multiple adenomas
43
solitary thyroid nodule DDx
``` Solitary nodule • Dominant nodule in multinodular goitre • Adenoma (hot or cold) • Cyst • Malignancy ```
44
investigating thyroid lumps
``` Bloods • TFTs: TSH, fT3, fT4 • Other: FBC, Ca2+, LFTs, ESR • Antibodies: anti-TPO, TSH Imaging • CXR: goitres and mets • High resolution US • CT • Radionucleotide (Tc or I) scan (hot vs. cold) Histology or cytology • FNAC (can’t distinguish adenoma vs. follicular Ca) • Biopsy Laryngoscopy • Pre-operative assessment of vocal cords ```
45
simple goitre
``` diffuse painless goitre Mass effects: - dysphagia - stridor - SVC obstruction Usually euthyroid ``` cause = iodine deficiency goitrogens - sulphonylureas give thyroxine or remove if pressure symptoms
46
multinodular goitre
evolves from long term simple goitre | treat as for that - thyroxine and remove if probs
47
toxic multinodular goitre
Multinodular goitre Thyrotoxicosis Uneven iodine uptake with hot nodule treat with carbimazole radioiodine or removal
48
Grave's
``` Diffuse goitre ¯c bruit Ophthalmopathy Dermopathy Thyrotoxicosis Assoc. ¯c other AI disease (T1DM, PA) ↑ uptake on radionucleotide scan ``` anti TSHr Propanolol Carbimazole Radioiodine Thyroidectomy
49
Hashimoto's thyroiditis
diffuse painless goitre thyrotoxic phase followed by hypothyroid may have viral trigger? anti TPO thyroxine
50
DeQuervain's thyroiditis
painful! diffuse goitre viral trigger esp URTI Cocksackie common trigger too start toxic then go hypo then resolve themselves supportive
51
subacute lymphocytic thyroiditis
Diffuse painless goitre May occur post-partum Thyrotoxicosis → hypo → eu resolves
52
follicular thyroid adenoma
Single thyroid nodule ± thyrotoxicosis (majority are cold) May get pressure symptoms remove half thyroid
53
thyroid cysts
s Solitary thyroid nodule Asympto or pressure symptoms Can → localised pain due to cyst bleed sort cyst
54
Riedel's thyroiditis
rare btw, just FYI Firm, fixed, irregular thyroid mass Mass effects Assoc. ¯c retroperitoneal fibrosis
55
malignant thyroid disease
papillary 80% Thyroglob marker follicular 10% thyroglob marker medullary - parafollicular C cells, calcitonin + CEA markers (screen phaeo pre op) lymphoma - MALToma in Hashimoto's anaplastic <1% for ALL -> remove nodes + thyroid, give radioiodine
56
5 reasons for thyroid surgery
* Mechanical obstruction * Malignancy * cosmetic * Medical Rx failure: thyrotoxicosis * Mediastinal extension: can’t monitor changes
57
thyroid pre op prep
• Render euthyroid pre-op ¯c antithyroid drugs § Stop 10 days prior to surgery (they ↑ vascularity) § Alternatively just give propronalol • Check for phaeo pre-op in medullary carcinoma • Laryngoscopy: check vocal cords pre- and post-op
58
thyroid surgery complications
early - reactive bleed, laryngeal oedema, recurrent laryngeal nerve palsy (hoarse), hypocalcaemia, hyperthyroidism late - low thyroid, recurrent high thyroid, scarring
59
dealing with hypocalcaemia
pt is tingling + has wheeze, Chvostek (zygoma tap) + Trousseau (BP cuff) signs give 10ml 10% cal gluconate
60
salivary gland enlargement
``` Whole gland § Parotitis § Sjogren’s / Sicca Syndrome § Sarcoid § Amyloid § ALL § Chronic liver disease § Anorexia or bulimia • Localised § Tumours § Stones ```
61
acute parotitis
Viral: mumps, coxsackie A, HIV • Bacterial: S. aureus - Assoc. ¯c calculi and poor oral hygiene
62
salivary calculi
* Recurrent unilateral swelling and pain * Worse on eating * Red, tender, swollen gland (80% submandibular) * Ix: plain x-ray or sialography * Rx: gland excision
63
salivary gland malignancies
* 80% are in the parotid (80% are superficial) * 80% are pleiomorphic adenomas * Deflection of ear outwards is classic sign * CN VII palsy = malignancy