Vascular Surgery Flashcards

(51 cards)

1
Q

modifiable and non modifiable atherosclerosis risk factors

A
Modifiable
• Smoking
• BP
• DM control
• Hyperlipidaemia
• ↓ exercise
Non-modifiable
• FH and PMH
• Male
• ↑ age
• Genetic
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2
Q

disease assoc with atherosclerosis and peripheral vascular diseae

A
  • IHD: 90%
  • Carotid stenosis:15%
  • AAA
  • Renovascular disease
  • DM microvascular disease
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3
Q

intermittent limb claudication

A

Cramping pain after walking a fixed distance
• Pain rapidly relieved by rest
• Calf pain = superficial femoral disease (commonest)
• Buttock pain = iliac disease (internal or common)

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4
Q

critical limb ischaemia

A

Fontaine 3 or 4
• European working group definition (1991)
• Ankle pressure <50mmHg (toe <30mmHg) and
either:
§ Rest pain requiring analgesia for ³2 wks
- Especially @ night
- Usually felt in the foot
- Pt. hangs foot out of bed
- Due to ↓ CO and loss of gravity help
§ Ulceration or gangrene

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5
Q

Leriche’s syndrome

A

Leriche’s Syndrome: Aortoiliac Occlusive Disease
• Atherosclerotic occlusion of abdominal aorta and iliacs
• Triad
§ Buttock claudication and wasting
§ Erectile dysfunction
§ Absent femoral pulse

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6
Q

Buerger’s diseaes

A

Buerger’s Disease: Thromboangiitis Obliterans
• Young, male, heavy smoker
• Acute inflammation and thrombosis of arteries and
veins in the hands and feet → ulceration and
gangrene

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7
Q

clinical examination Buerger’s diseaes

A

• Pulses: loss of pulses and ↑ CRT (norm ≤2sec)
• Ulcers: painful, punched-out, on pressure points
• Nail dystrophy / Onycholysis
• Skin: cold, white, atrophy, absent hair
• Venous guttering
• Muscle atrophy
• ↓ Buerger’s Angle
§ ≥90: normal
§ 20-30: ischaemia
§ <20: severe ischaemia
• +ve Buerger’s Sign
§ Reactive hyperaemia due to accumulation of
deoxygenated blood in dilated capillaries

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8
Q

classification scores x 2 peripheral vascular diseas

A
Fontaine
• Asympto (subclinical)
• Intermittent claudication
§ >200m
§ <200m
• Ischaemic rest pain
• Ulceration / gangrene
Rutherford
• Mild claudication
• Moderate claudication
• Severe claudication
• Ischaemic rest pain
• Minor tissue loss
• Major tissue loss
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9
Q

chonic limb ischaemia

A

Normal Doppler: triphasic
• Mild stenosis: biphasic
• Severe stenosis: monophasic

ABPI
claud at <0.8
rest pain at <0.6
ulcer/gangrene <0.3
NB. Falsely high results may be obtained in DM / CRF
due to calcification of vessels >1.4 ABPI

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10
Q

investigating suspected chronic limb ischaeia

A

Walk test
• Walk on treadmill @ certain speed and incline to
establish maximum claudication distance.
• ABPI measured before and after: 20% ↓ is sig

Bloods
• FBC + U+E: anaemia, renovascular disease
• Lipids + glucose
• ESR: arteritis
• G+S: possible procedure

Imaging: assess site, extent and distal run-off
• Colour duplex US
• CT / MR angiogram
• Digital subtraction angiography
§ Invasive \ not commonly used for Dx only.
§ Used when performing therapeutic
angioplasty or stenting

Other
• ECG: ischaemia

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11
Q

cons med surg mnagement chronic limb ischaemia

A

Conservative Mx
• Most pts. ¯c claudication can be managed conservatively
• ↑ exercise and employ exercise programs
• Stop smoking
• Wt. loss
• Foot care
• Prog: 1/3 improve, 1/3 stay the same, 1/3 deteriorate
Medical Mx
• Risk factors: BP, lipids, DM
§ β-B don’t worsen intermittent claudication but use
¯c caution in CLI
• Antiplatelets: aspirin / clopidogrel
• Analgesia: may need opiates
• (Parenteral prostanoids ↓ pain in pts. unfit for surgery)
Endovascular Mx
• Percutaneous Transluminal Angioplasty ± stenting
• Good for short stenosis in big vessels: e.g. iliacs, SFA
• Lower risk for pt.: performed under regional anaesthesia
as day case
• Improved inflow → ↓ pain but restoration of foot pulses is
required for Rx of ulceration / gangrene.

consdier surgical reconstruction if v v severe

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12
Q

surgical reconstruction of limb vasc PVD

A

if v bad claud on <100m walk

Pre-op assessment
• Need good optimisation as likely to have cardiorespiratory
co-morbidities.
Practicalities
• Need good proximal supply and distal run-off
• Saphenous vein grafts preferred below the IL
• More distal grafts have ↑ rates of thrombosis
Classification
• Anatomical: fem-pop, fem-distal, aortobifemoral
• Extra-anatomical: axillo-fem / -bifem, fem-fem crossover
Other
• Endarterectomy: core-out atheromatous plaque
• Sympathectomy: chemical (EtOH injection) or surgical
§ Caution in DM ¯c neuropathy
• Amputation

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13
Q

prognosis following chornic limb ischaemia or amputation

A

just FYI

1yr after onset of CLI
• 50% alive w/o amputation
• 25% will have had major amputation
• 25% dead (usually MI or stroke)
Following amputation
• Perioperative mortality
§ BK: 5-10%
§ AK: 15-20%
• 1/3 → complete autonomy
• 1/3 → partial autonomy
• 1/3 → dead
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14
Q

classify severity of limb ischaeia

A

• Incomplete: limb not threatened
• Complete: limb threatened
§ Loss of limb unless intervention w/i 6hrs
• Irreversible: requires amputation

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15
Q

causes of acute limb ischaemia

A
Thrombosis in situ (60%)
§ A previously stenosed vessel ¯c plaque rupture
§ Usually incomplete ischaemia
• Embolism (30%)
§ 80% from left atrium in AF
§ Valve disease
§ Iatrogenic from angioplasty / surgery
§ Cholesterol in long bone #
§ Paradoxical (venous via PFO)
§ Typically lodge at femoral bifurcation
§ Often complete ischaemia
• Graft / stent occlusion
• Trauma
• Aortic dissection
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16
Q

presentation of acute limb ischaemia

A
Pale
• Pulseless
• Perishingly cold
• Painful
• Paraesthesia
• Paralysis
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17
Q

thrombosis vs embolus acute limb ischaemia

A

embolus more acute and sudden, more profound, but contralateral pulses present

need embolectomy and warfarin

for thrombosis they needthrombolysis and bypass surgery

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18
Q

investigating acute limb ischaemia

A
• Blood
§ FBC, U+E, INR, G+S
§ CK
• ECG
• Imaging
§ CXR
§ Duplex doppler
§ CT angio
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19
Q

management acute limb ischaemia

A

In an acutely ischaemic limb discuss immediately ¯c a
senior as time is crucial.
• NBM
• Rehydration: IV fluids
• Analgesia: morphine + metoclopramide
• Abx: e.g. co-amoxiclav if signs of infection
• Unfractionated heparin IVI: prevent extension
• Complete occlusion?
§ Yes: urgent surgery: embolectomy or bypass
§ No: angiogram + observe for deterioration

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20
Q

management of embolic acute limb ischameia

A
Embolus Mx
1. Embolectomy
§ Under regional anaesthesia or GA
§ Wire fed through embolus
§ Fogarty catheter fed over the top
§ Balloon inflated and catheter withdrawn,
removing the embolism.
§ Adequacy confirmed by on-table angiography
2. Thrombolysis
§ Consider if embolectomy unsuccessful
§ E.g. local injection of TPA
3. Other options
§ Emergency reconstruction
§ Amputation
Post-embolectomy
• Anticoagulate: heparin IVI → warfarin
• ID embolic source: ECG, echo, US aorta, fem and
pop
• Complications
§ Reperfusion injury
- Local swelling → compartment
syndrome
- Acidosis and arrhythmia 2O to ↑K
- ARDS
- GI oedema → end
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21
Q

managemetn of thrombotic acute limb iscahemia

A
Thrombosis Mx
• Emergency reconstruction if complete occlusion
• Angiography + angioplasty
• Thrombolysis
• Amputation
Manage Cardiovascular Risk Factors
22
Q

carotid artery disease

A
Presentation
• Bruit
• CVA/TIA
Ix
• Duplex carotid Doppler
• MRA
Mx
Conservative
• Aspirin or clopidogrel
• Control risk factors
Surgical: Endarterectomy
• Symptomatic (ECST, NASCET)
§ ≥70% (5% stroke risk per yr)
§ ≥50% if low risk (<3%, typically <75yrs)
§ Perform w/i 2wks of presentation
• Asymptomatic (ACAS, ACST)
23
Q

complications of cartoid endartecotmy

A
  • Stroke or death: 3%
  • HTN: 60%
  • Haematoma
  • MI
  • Nerve injury
  • Hypoglossal: ipsilateral tongue deviation
  • Great auricular: numb ear lobe
  • Recurrent laryngeal: hoarse voice, bovine cough

NB some would consider stenting instead but limited data yet

24
Q

define and categorise aneurysm

A

Definition
• Abnormal dilatation of a blood vessel >50% of its
normal diameter.
Classification
• True Aneurysm
§ Dilatation of a blood vessel involving all layers
of the wall and is >50% of its normal diameter
§ Two different morphologies
- Fusiform: e.g AAA
- Saccular: e.g Berry aneurysm
• False Aneurysm
§ Collection of blood around a vessel wall that
communicates ¯c the vessel lumen.
§ Usually iatrogenic: puncture, cannulation
• Dissection
§ Vessel dilatation caused by blood splaying
apart the media to form a channel w/i the
vessel wall.

25
causes of aneurysm
``` Causes • Congenital § ADPKD → Berry aneurysms § Marfan’s, Ehlers-Danlos • Acquired § Atherosclerosis § Trauma: e.g. penetrating trauma § Inflammatory: Takayasu’s aortitis, HSP § Infection - Mycotic: SBE - Tertiary syphilis (esp. thoracic) ```
26
complications of aneurysms
``` Rupture • Thrombosis • Distal embolization • Pressure: DVT, oesophagus, nutcracker syndrome • Fistula (IVC, intestine) ```
27
summarise treatment etc of popliteal aneurysm
``` • Less common cf. AAA • 50% of pts. ¯c popliteal aneurysm also have AAA Presentation • Very easily palpable popliteal pulse • 50% bilateral • Rupture is relatively rare • Thrombosis and distal embolism is main complication § → acute limb ischaemia Mx • Acute: embolectomy or fem-distal bypass • Stable § Elective grafting + tie off vessel § Stenting ```
28
presentation AAA
``` Usually asympto: discovered incidentally • May → back pain or umbilical pain radiating to groin • Acute limb ischaemia • Blue toe syndrome: distal embolisation • Acute rupture ```
29
vascular rv size of AAA on USS
5.5cm+ is urgent referral
30
inv and exam AAA
``` Expansile mass just above the umbilicus • Bruits may be heard • Tenderness + shock suggests rupture Ix • AXR: calcification may be seen • Abdo US: screening and monitoring • CT / MRI: gold-standard • Angiography § Won’t show true extent of aneurysm due to endoluminal thrombus. § Useful to delineate relationship of renal arteries ```
31
management of AAA
Conservative • Manage cardiovascular risk factors: esp. BP § <4cm: yearly monitoring § 4-5.5cm: 6 monthly monitoring Surgical • Aim to treat aneurysm before it ruptures. § Elective mortality: 5% § Emergency mortality: 50% • Operate when risk of rupture > risk of surgery ``` • Indications § Symptomatic (back pain = imminent rupture) § Diameter >5.5cm § Rapidly expanding: >1cm/yr § Causing complications: e.g. emboli • Open or EVAR § EVAR has ↓ perioperative mortality ``` UK men screened once at 65yrs
32
AAA ruptured - managment
High flow O2 • 2 x large bore cannulae in each ACF § Give fluid if shocked but keep SBP <100mmHg § Give O- blood if desperate § Blood: FBC, U+E, clotting, amylase, xmatch 10u • Instigate the major haemorrhage protocol • Call vascular surgeon, anaesthetist and warn theatre • Analgesia • Abx prophylaxis: cef + met • Urinary catheter + CVP line • If stable + Dx uncertain: US or CT may be feasible • Take to theatre: clamp neck, insert dacron graf
33
thoracic aortic dissection
Sudden onset, tearing chest pain § Radiates through to the back § Tachycardia and hypertension (1O + sympathetic) ``` • Distal propagation → sequential occlusion of branches § Left hemiplegia § Unequal arm pulses and BP § Paraplegia (anterior spinal A.) § Anuria ``` ``` • Proximal propagation § Aortic regurgitation § Tamponade • Rupture into pericardial, pleural or peritoneal cavities § Commonest cause of death ```
34
classification system for aortic dissection
``` Stanford Classification Type A: Proximal • 70% • Involves ascending aorta ± descending • Higher mortality due to probable cardiac involvement • Usually require surgery Type B: Distal • 30% • Involves descending aorta only: distal to L SC artery • Usually best managed conservatively ```
35
inv and management aortic dissection
Resuscitate Investigate • Bloods: x-match 10u, FBC, U+E, clotting, amylase • ECG: 20% show ischaemia due to involvement of the coronary ostia • Imaging § CXR § CT/MRI: not if haemodynamically unstable § TOE: can be used if haemodynamically unstable Treat • Analgesia • ↓SBP § Labetalol or esmolol (short t½) § Keep SBP 100-110mmHg • Type A: open repair § Acute operative mortality: <25% • Type B: conservative initially § Surgery if persistent pain or complications § Consider TEVAR if uncomplicated
36
classify gangrene x 3
``` Classification • Wet: tissue death + infection • Dry: tissue death only • Pregangrene: tissue on the brink of gangrene Presentation • Black tissues ± slough • May be suppuration ± sepsis ```
37
gas gangrene
``` Clostridium perfringes myositis • RFs: DM, trauma, malignancy • Presentation § Toxaemia § Haemolytic jaundice § Oedema § Crepitus from surgical emphysema § Bubbly brown pus • Rx § Debridement (may need amputation) § Benzylpenicillin + metronidazole § Hyperbaric O2 ```
38
synergistic gangrene
``` Synergistic Gangrene • Involves aerobes + anaerobes • Fournier’s: perineum • Meleney’s: post-op ulceration • Both progress rapidly to necrotising fasciitis + myositis Mx • Take cultures • Debridement (including amputation ```
39
cause of varicose veins
failure of valves between deep and superficial veins leads to engorgement of superficial veins
40
risk factors varicose veins
``` Primary • Idiopathic (congenitally weak valves) § Prolonged standing § Pregnancy § Obesity § OCP § FH • Congenital valve absence (v. rare) Secondary • Valve destruction → reflux: DVT, thrombophlebitis • Obstruction: DVT, foetus, pelvic mass • Constipation • AVM • Overactive pumps (e.g. cyclists) ```
41
signs varciose veins
``` Skin changes § Venous stars § Haemosiderin deposition § Venous eczema § Lipodermatosclerosis (paniculitis) § Atrophie blanche • Ulcers: medial malleolus / gaiter area • Oedema • Thrombophlebitis ```
42
varicose veins inv and referral
``` • Duplex ultrasonography § Anatomy § Presence of incompetence § Caused by obstruction or reflux • Surgery: FBC, U+E, clotting, G+S, CXR, ECG ``` ``` Referral Criteria • Bleeding • Pain • Ulceration • Superficial thrombophlebitis • Severe impact on QoL ```
43
management varicose veins
``` Treat any contributing factors § Lose weight § Relieve constipation • Education § Avoid prolonged standing § Regular walks • Class II Graduated Compression Stockings § 18-24mmHg § Symptomatic relief and slows progression • Skin care § Maintain hydration ¯c emollients § Treat ulcers rapidly ``` can inject sclerosant or do radiofreq ablation surg rarely done as ineffective but could ligate
44
complications varicose vein surgery /procedure
``` Post-op • Bandage tightly • Elevate for 24h • Discharged ¯c compression stockings and instructed to walk daily. Complications • Haematoma (esp. groin) • Wound sepsis • Damage to cutaneous nerve (e.g. long saphenous) • Superficial thrombophlebitis • DVT • Recurrence: may approach 50% ```
45
causes of leg ulcers
``` Venous: commonest • Arterial: large or small vessel • Neuropathic: EtOH, DM • Traumatic: e.g. pressure • Systemic disease: e.g. pyoderma gangrenosum • Neoplastic: SCC ```
46
venous vs arterial vs neuropathic ulcers
``` Venous: 75% painless, shallow usually medial ankle haemosiderin deposition and lipodermatosclerosis • RFs: venous insufficiency, varicosities, DVT, obesity ``` ``` Arterial: 2% • Painful, deep, punched out lesions • Occur @ pressure points § Heel § Tips of, and between, toes § Metatarsal heads (esp. 5th) • Other signs of chronic leg ischaemia ``` Neuropathic • Painless insensate surrounding skin • Warm foot good pulses Complications • Osteomyelitis • Development of SCC in the ulcer (Marjolin’s ulcer)
47
inv leg ulcers
ABPI if possible • Duplex ultrasonography • Biopsy may be necessary § Look for malignant change: Marjolin’s ulce
48
manage venous ulcers
• Refer to leg ulcer community clinic • Focus on prevention § Graduated compression stockings • Optimise risk factors: nutrition, smoking ``` Specific Rx • Analgesia • Bed Rest + Elevate leg • 4 layer graded compression bandage (if ABPI >0.8) • Pentoxyfylline PO § ↑ microcirculatory blood flow § Improves healing rates ```
49
DDx bilateral leg swelling
``` Bilateral right heart failure venous insufficiency drugs - nifedipine, amlodipine nephrotic syndrome liver failure myxoedema - thyroid hypo/hyperthyroid lymphoedema plasma protein loss (low albumin) ```
50
unilateral leg swelling DDx
Venous insufficiency • DVT • Infection or inflammation • Lymphoedema
51
lymphoedema causes
can be familial otherwise ``` • Fibrosis: e.g. post-radiotherapy • Infiltration § Ca: prostate, lymphoma § Filariasis: Wuchereria bancrofti • Infection: TB • Trauma: block dissection of lymphatics ```