Upper GI Surger Flashcards

(58 cards)

1
Q

oesophageal margins

A

C6 to T10

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2
Q

stratify causes of dysphagia x3 and give examples of causes

A

inflammatory - infection (tonsillitis, pharyngitis), oesophagitis, GORD, oral candidiasis, aphthous ulcers

neuro local - achalasia, spasm, nutcracker oesophagus, MND palsies

neuro systemic - systemic sclerosis, mya gravis

mechanical obstruction
can be luminal
mural - oesophageal pouch,
extramural - lung ca, goitre, hiatus hernia, aorta

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3
Q

investigating dysphagia

A

OGD
barium swallow
manometry

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4
Q

achalalsia classic history

A
dysphagia to fluids then solids 
regurg at night
weight loss
caused by degen in myenteric plexus
often unknown cause

can get oesophageal SCCs

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5
Q

achalasia inv findings

A

§ Ba swallow: dilated tapering oesophagus
- Bird’s beak!
§ Manometry: failure of relaxation + ↓ peristalsis
§ CXR: widened mediastinum, double RH border
§ OGD: exclude malignancy

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6
Q

treating achalasia

A

botox
endoscopic balloon dilatation
Heller’s cardiomyotomy

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7
Q

pharyngeal pouch presentation and treatment

A

Pres: Regurgitation, halitosis, gurgling sounds

• Rx: excision, endoscopic stapling

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8
Q

diffuse oesophageal spasm

A

corkscrew oesophagus on barium swallow

intermittent severe chest pain and dysphagia

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9
Q

oesophageal rupture

A

usually iatrogenic
Features
• Odonophagia
• Mediastinitis: tachypnoea, dyspnoea, fever, shock
• Surgical emphysema
Mx
• Iatrogenic: PPI, NGT, Abx
• Other: resus, PPI, Abx, antifungals, debridement +
formation of oesophago-cutaneous fistula ¯c T-tube

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10
Q

Plummer Vinson Syndrome

A

Severe IDA → hyperkeratinisation of upper 3rd of

oesophagus → web formation

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11
Q

risk factors oesophageal cancer

A

achalasia
GORD
Plummer Vinson
smoking

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12
Q

oesophageal cancers by risk factor

A

GORD - adenocarcinoma

smoking - SCC

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13
Q

presentation oesophageal cancer

A
progressive dysphagia, starts with fluids and progresses to less and less
FLAWS symptoms 
hoarseness
retrosternal chest pain
cough
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14
Q

diagnosing oesophageal cancer

A

FBC - anaemia
LFT - liver mets

OGD + biopsy

CT staging
lap

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15
Q

treatment oesophageal cancers

A

MDT approach
poor prognosis
neoadjuvant Ctherapy
oesophagectomy

palliative - stenting, radioT

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16
Q

risk factors GORD

A
Hiatus hernia
• Smoking
• EtOH
• Obesity
• Pregnancy
• Drugs: anti-AChM, nitrates, CCB, TCAs
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17
Q

complications of GORD

A

Barrett’s
ulceration
stricture
cancers

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18
Q

DDx GORD

A

consider oesophagitis - infection
IBD
caustic substances
cancers

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19
Q

when to give an OGD with GORD

A
OGD if:
§ >55yrs
§ Persistent symptoms despite Rx
§ Anaemia
§ Loss of wt.
§ Anorexia
§ Recent onset progressive symptoms
§ Melaena
§ Swallowing difficulty
§ OGD allows grading by Los Angeles
Classification
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20
Q

GORD management

A
stop smoking, coffee, alcohol
raise head of bed 
alter diet, no spice
PPIs
Gaviscon
small reg meals, never eat before bed
avoid NSAIDs, calantags, antimuscarinics

Nissen fundoplication (refractory to medical treatment, pH confirmed)

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21
Q

hiatus hernia investigations

A
CXR: gas bubble and fluid level in chest
• Ba swallow: diagnostic
• OGD: assess for oesophagitis
• 24h pH + manometry: exclude dysmotility or
achalasia
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22
Q

types of hiatus hernia

A

sliding, rolling, mixed

sliding most common, GORD assoc, medical management

rolling -some stomach in chest and can strangulate

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23
Q

treating hiatus hernia

A

• Lose wt.
• Rx reflux
• Surgery if intractable symptoms despite medical Rx.
§ Should repair rolling hernia (even if asympto)
as it may strangulate

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24
Q

gastric vs duodenal ulcer

A
DU
- Before meals and at night
- Relieved by eating
§ GU
- Worse on eating (→ ↓ wt.)
- Relieved by anatacids

duodenal are commoner

25
complications of GI ulcers
bleeding perforation gastric outflow obstruction malignancy
26
investigating peptic ulcers
FBC - microcytic anaemia, raised urea if GI bleed OGD after 2 weeks no PPI breath test H pylori ulcer biopsy gastrin levels if suspect Zoll El syndrome suspected
27
peptic ulcer disease treatment
avoid risk factors lanzoprazole eradication therapy surgery: vagotomy - cut vagal nerve supply to reduce acid secretion, widening of outlet needed too antrectomy and anastom
28
complications of peptic ulcer surgery (antrectomy, vagotomy)
``` Ca: ↑ risk of gastric Ca • Reflux or bilious vomiting (improves ¯c time) • Abdominal fullness • Stricture • Stump leakage ```
29
metabolic complications of antrectomy / vagotomy
Dumping syndrome § Abdo distension, flushing, n/v, fainting, sweating § Early: osmotic hypovolaemia § Late: reactive hypoglycaemia • Blind loop syndrome → malabsorption, diarrhoea § Overgrowth of bacteria in duodenal stump • Vitamin deficiency § ↓ parietal cells → B12 deficiency § Bypassing proximal SB → Fe + folate deficiency § Osteoporosis • Wt. loss: malabsorption of ↓ calories intake
30
upper GI bleeding management pathway
RESUS • Head down • 100% O2, protect airway • 2 x 14G cannulae + IV crystalloid infusion up to 1L. • Bloods: FBC, U+E (↑ urea), LFTs, clotting, x-match 6u, ABG, glucose BLOOD if shocked (O neg and send G+S) maintenance and correct blood abnormalities (thiamine if alcohol) terlipressin and abx if variceal URGENT OGD
31
OGD variceal treatment
2 of: banding, sclerotherapy, adrenaline, coagulation • Balloon tamponade ¯c Sengstaken-Blakemore tube § Only used if exsanguinating haemorrhage or failure of endoscopic therapy • TIPSS if bleeding can’t be stopped endoscopically
32
OGD if vessel or ulcer bleeding
* Adrenaline injection * Thermal / laser coagulation * Fibrin glue * Endoclips
33
indications for surgery with upper GI bleed
``` Re-bleeding • Bleeding despite transfusing 6u • Uncontrollable bleeding at endoscopy • Initial Rockall score ≥3, or final >6. • Open stomach, find bleeder and underrun vessel ```
34
normal history with upper GI bleed
``` • Previous bleeds • Dyspepsia, known ulcers • Liver disease or oesophageal varices • Dysphagia, wt. loss • Drugs and EtOH • Co-morbidities blood thinning meds ```
35
on examination acute GI bleed
``` Signs of CLD • PR: melaena • Shock? § Cool, clammy, CRT>2s § ↓BP (<100) or postural hypotension (>20 drop) § ↓ urine output (<30ml/h) § Tachy ```
36
differentials upper GI bleed
* peptic ulcer: 40% ( * Acute erosions / gastritis:20% * Mallory-Weiss tear: 10% * Varices: 5% * Oesophagitis: 5% * Ca stomach / oesophagus:<3%
37
causes of portal HTN
• Pre-hepatic: portal vein thrombosis • Hepatic: cirrhosis (80% in UK), schisto (commonest worldwide), sarcoidosis. • Post-hepatic: Budd-Chiari, RHF, constrict pericarditis
38
what is the TIPSS procedure?
IR creates artificial channel between hepatic vein and portal vein → ↓ portal pressure. • Colapinto needle creates tract through liver parenchyma which is expand using a balloon and maintained by placement of a stent. • Used prophylactically or acutely if endoscopic therapy fails to control variceal bleeding.
39
perforated peptic ulcer presentation
• Sudden onset severe pain, beginning in the epigastrium and then becoming generalised. • Vomiting • Peritonitis consider Pancreatitis • Acute cholecystitis • AAA • MI
40
peptic ulcer perf investigations
bloods G+S, clotting, coag urine dip erect CXR (stand for 15 mins) - air under diaphragm Rigler's sign - air either side of gut wall
41
managing peptic ulcer perf
``` NBM fluid resus abx analgesia antiemetic ``` can consider conservative if no peritonism (1/2 will self-seal) surgery- duodenal = washout and omental repair, gastric - excise and repair screen ulcer for cancers treat afterwards for H pylori
42
causes of gastric outlet obstruction
cancers or | late peptic ulcer causing strictures
43
presentation gastric outlet obstruction
• Hx of bloating, early satiety and nausea ``` • Outlet obstruction § Copious projectile, non-bilious vomiting a few hrs after meals. § Contains stale food. § Epigastric distension f ```
44
investigation findings in gastric outlet obstruction
ABG: Hypochloraemic hypokalaemic met alkalosis • AXR § Dilated gastric air bubble, air fluid level § Collapsed distal bowel • OGD • Contrast meal
45
treating gastric oulet obstruction
``` • Correct metabolic abnormality: 0.9% NS + KCl • Benign § Endoscopic balloon dilatation § Pyloroplasty or gastroenterostomy • Malignant § Stenting § Resection ```
46
classic pyloric stenosis presentation
6-8wks • Projectile vomiting minutes after feeding • RUQ mass: olive • Visible peristalsis
47
pyloric stenosis inv and management
Dx • Test feed: palpate mass + see peristalsis • Hypochloraemic hypokalaemic metabolic alkalosis • US Mx • Resuscitate and correct metabolic abnormality • NGT • Ramstedt pyloromyotomy: divide muscularis propria
48
classification of gastric cancers
Borrmann ``` 4 types • Polypoid / fungating • Excavating • Ulcerating and raised • Linitis plastica: leather-bottle like thickening ¯c flat rugae ```
49
risk factors gastric cancre
``` diet smoking ulcers metaplasia FH ```
50
symptoms and signs of gastric cancers
``` Usually present late • Wt. loss + anorexia • Dyspepsia: epigastric or retrosternal pain/discomfort • Dysphagia • vomiting and nausea ``` ``` Anaemia • Epigastric mass • Jaundice • Ascites • Hepatomegaly • Virchow’s node (= Troisier’s sign) • Acanthosis nigricans ```
51
complications of gastric cancers
perf bleed obstruction
52
investigating gastric cancer
``` Bloods § FBC: anaemia § LFTs and clotting • Imaging § CXR: mets § USS: liver mets § Gastroscopy + biopsy § Ba meal • Staging § Endoluminal US § CT/MRI § Diagnostic laparoscopy ```
53
gastric cancer treatment
if very lucky can do gastrectomy and cure palliative care stenting
54
GI stromal tumour
``` Arise from intestinal cells of Cajal § Located in muscularis propria § Pacemaker cells • OGD: well-demarcated spherical mass ¯c central punctum ``` mass effects bleeding
55
carcinoid tumours
enterchromaffin cell origin secrete hormones flushing diarrhoea mainly paroxysms as hormones released in random bursts
56
gastric lymphoma
most common extranodal site often gastric MALToma due to H pylori eradication can cure
57
Zollinger Ellison syndrome
tumour secretes gastrin refractory peptic ulcers diagnose gastrin levels MRI/CT somatostatin receptor scintigraphy (also used for finding carcinoid) PPI and resect
58
indications bariatric surgery
• All the criteria must be met § BMI ≥40 or ≥35 ¯c significant co-morbidities that could improve ¯c ↓ wt. § Failure of non-surgical Mx to achieve and maintain clinically beneficial wt. loss for 6mo. § Fit for surgery and anaesthesia § Integrated program providing guidance on diet, physical activity, psychosocial concerns and lifelong medical monitoring § Well-informed and motivated pt. • If BMI >50, surgery is 1st-line Rx