SUPPOSITORIES Flashcards
(80 cards)
Are solid dosage forms in which one
or more active pharmaceutical
ingredients (APIs) are dispersed in a
suitable base molded or otherwise
formed into a suitable shape for
insertion into the rectum to provide
local or systemic effect.
SUPPOSITORIES
Are solid dosage forms intended for
insertion into body orifices where they melt, soften, or dissolve and exert localized or systemic effects.
SUPPOSITORIES
Suppositories is derived from the Latin word ______ which means “to place
under”, as from sub (under) and
ponere (to place).
SUPPONERE
What is the meaning of supponere?
TO PLACE UNDER
Used rectally, vaginally, and occasionally
urethrally.
SUPPOSITORIES
pain, constipation, irritation,
itching, and inflammation associated with
hemorrhoids or other anorectal d
RECTAL
contraceptives, antiseptics in
feminine hygiene, antibacterial
VAGINAL
comes in various shapes
and weights. The shape and size must be
such that it can be easily inserted into the
intended orifice without causing undue
distension, and once inserted, it must be
retained for the appropriate period.
SUPPOSITORIES
Are intended for insertion into body
orifices where they melt, soften, or
dissolve and exert localized or systemic
effects.
SUPPOSITORIES
Types of Suppositories
RECTAL
VAGINAL
URETHRAL
BURGINARIUM
Are inserted into the rectum with the fingers.
RECTAL
• Are cylindrical and have one or both ends tapered.
• Some are shaped like a bullet, a torpedo, or the little finger.
• Length: Usually about 32 mm (1 ½inches)
• Weight: Adult: 2 grams - when made of
cocoa butter (pencil-like shape)
• Infants: 1 grams
RECTAL
Also called Pessary or Pessaries
VAGINAL
• Are usually globular, oviform, or cone-
shaped
• Weight: about 5 grams - when made
cocoa butter base.
VAGINAL
Urethral is also called as?
BOUGIES
Are slender, pencil-shaped intended for
insertion into the male or female urethra.
Male:
• Diameter - 3-6 mm
• Length: 140 mm (14 cm)
• Weight: about 4 grams - when made of
cocoa butter
Female: Length: 70 mm (7 cm)
• Weight: about 2 grams - when made of
cocoa butter
URETHRAL
same as urethral suppositories but shorter and thinner.
BURGINARIUM
same as urethral suppositories but shorter and thinner.
BURGINARIUM
Vaginal suppositories is also called as?
PESSARY OR PESSARIES
Are slender, pencil-shaped intended for
insertion into the male or female urethra.
Male:
• Diameter - 3-6 mm
• Length: 140 mm (14 cm)
• Weight: about 4 grams - when made of
cocoa butter
Female: Length: 70 mm (7 cm)
• Weight: about 2 grams - when made of
cocoa butter
URETHRAL
The most widely used suppository
base.
COCOA BUTTER (THEOBROMA OIL)
Good base for rectal suppositories,
but it is less ideal for vaginal and
urethral suppositories.
COCOA BUTTER
Good base for rectal suppositories,
but it is less ideal for vaginal and
urethral suppositories.
COCOA BUTTER
______ can replace to coca butter to replace part of it to obtain proper melting point?
WHITE WAX