Suspected Seizure Flashcards

1
Q

What is the initial management of status epilepticus?

A

After 5 min of fitting

If vascular access:
IV/IO lorazepam (0.1 mg/kg)

If no:
Buccal Midazolam (0.5mg/kg)
Rectal Diazepam (0.5mg/kg)
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2
Q

What is the second stage of management of status epilepticus if patient is still fitting?

A

After 10 mins of fitting

IV/IO Lorazepam (0.1 mg/kg)
CALL FOR SENIOR HELP

If not on phenytoin: Prepare phenytoin
If already on phenytoin: Prepare phenobarbitone

Optional: Paraldehyde (0.8ml/kg 50:50 infusion with oil) Give while preparing phenytoin (DO NOT DELAY PHENYTOIN)

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3
Q

What is the third stage of management of status epilepticus?

A

Reconfirm it is an epilectic seizure
Seek anaesthetic/ICU advice

Not on phenytoin: Give phenytoin (20mg/kg) given IV/IO over 20 minutes

On phenytoin: Give phenobarbitone (20mg/kg) given IV/IO over 20 minutes

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4
Q

What is the fourth step in the management of status epilepticus?

A

Anaesthetist must be present

Rapid Sequence Induction (RSI) with thiopental

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5
Q

Child’s GCS

Eye Opening

A
E4 Spontaneous
E3 To voice
E2 To pain
E1 None
C Eyes closed (by swelling or bandage)
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6
Q

Child’s GCS

Motor

A

M6 Obeys commands Normal spontaneous movements
M5 Localises to supraorbital pain (>9 months of age) or withdraws to touch
M4 Withdraws from nailbed pain
M3 Flexion to supraorbital pain (decorticate)
M2 Extension to supraorbital pain (decerebrate)
M1 No response to supraorbital pain (flaccid)

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7
Q

Child’s GCS

Verbal

A

V5 Orientated Alert, babbles, coos, words or
(in person or place or address) sentences to usual ability (normal)
V4 Confused Less than usual ability, irritable cry
V3 Inappropriate words Cries to pain
V2 Incomprehensible sounds Moans to pain
V1 No response to pain
T Intubated

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8
Q

Differential Diagnosis for a child with seizure

A
Febrile seizure
Encephalopathy
Encephalitis/meningitis
Post-ictal
Sepsis/shock 
Brain tumour
Epilepsy
Metabolic disorder - The younger the unconscious child, the higher the possibility of a metabolic cause for being persistently unconscious/encephalopathic or intractable seizures. Family history of infant deaths.
Poisoning/intoxication - Similarly, should be actively ruled out in any patient, if persistent encephalopathic

Other conditions to consider in an unconscious child include: Trauma/ head injury, hypertension, hydrocephalus

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9
Q

Questions to ask parents about a seizure

A

Prior to the episode
During Episode
Post-Episode
Recent Illness

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10
Q

Prior to episode (10)

A
Behavioural change
Health that day
Circumstances
Time of episode
Setting
Activity at onset
Warning: visual, hearing,
fear, sweaty, light headedness
Objective warning
Triggers
Time of last meal
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11
Q

During episode (14)

A
Onset- sudden?
Unresponsive
Awareness
Symmetrical?
Facial movement
Eye movements
Posturing
Motor movements
Clonic/ myoclonic/spasm or tonic
Breathing changes
Incontinence
Autonomic
Visual disturbance
Duration of seizure
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12
Q

Post-Episode (7)

A
Sleepy/disorientated
Nausea, vomiting
Amnesia for events
Strange behaviour
Weakness
Injuries: tongue
Time to recovery
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13
Q

Recent Illness (11)

A
fever
chestiness
diarrhoea
weight loss
Recent headaches
Head injury/trauma
visual disturbances
vomiting or nausea personality change
poor co-ordination
new weakness
Taken drug/substance
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14
Q

What is epilepsy?

A

Tendancy to intermittent abnormal electrical brain activity

1% of children will have a seizure (not associated with fever) by the age of 14

At least two unprovoked seizures occurring >24 h apart
One unprovoked seizure and a probability of further seizures similar to the general recurrence risk (at least 60%) after two unprovoked seizures, occurring over the next 10 years
Diagnosis of an epilepsy syndrome

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15
Q

What is the difference between partial epilepsy and generalised epilepsy?

A

Partial epilepsy: Can be localised to one part of a hemisphere

Generalised: Cannot be localised

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16
Q

What is the difference between complex and simple seizures?

A

Complex: Loss of consciousness

Simple: No loss of consciousness

17
Q

Seizures in generalised epiliepsy (4):

A

Tonic/Clonic: Limb stiffness (tonic), jerking forcefully (clonic) with LOC

Absences (petit mal): Brief(10secs) pauses (stop mid sentence), eyes may roll up, unaware of the attack

Infantile Spasms/West syndrome: Clusters of head nodding (Salaam attacks) and arm jerks every 3-30 seconds; Peak age: 5 months; reduced IQ in ~70%; Rx 1,prednisolone 2,vigabitrin (ACTH)

Myoclonic seizures: 1-4 years e.g thrown suddenly to the ground Rx: Valproate

18
Q

What is a simple febrile convulsion?

A

Single tonic-clonic, symmetrical generalised seizure Last <15 minutes
Occurrs as temperature rapidly rises in a febrile illness Typically in a normally developing child (6months - 6years)

~3% of children have at least one febrile convulsion

19
Q

When could a febrile convulsion be more sinister?

A

Focal CNS signs or CNS abnormality
Previous history of epilepsy
Seizure last >15 mins
There is >1 attack in 24 hours

Think:
Meningo-encephalitis, CNS lesion, epilepsy, trauma, ↓glucose, ↓Ca2+, ↓Mg2+

20
Q

Differntial diagnosis for epilepsy

A
Arrythmias (prolonged QT)
Migraine
Narcolepsy
Night terrors
Reflex anoxic seizures (excessive vagus nerve activity)
Munchausen's
21
Q

What is a complex febrile seizure?

A

Last >15 minutes
More than 1 episode in 24 hours
Associated with post ictal neuroligical abnormalities

Simple: <15 mins, one within 24 hours,
Not caused by an acute disease of the nervous system, in a child aged 6 months to 5 years, with no neurologic deficits

22
Q

What are the indications for an urgent CT head for someone who has had an afebrile seizure?

A

Encephalopathic or coma
Suspected raised intracranial pressure
Progressive neurological deficit

23
Q

What are the indications for an elective CT head for someone who has had an afebrile seizure?

A

In a child under 2 year of age at onset
hard focal neurological signs
a focal epilepsy
associated significant learning difficulties
an epilepsy resistant to full doses of 2 appropriate drugs

24
Q

In what circumstances is an EEG indicated?

A

Urgent Indications:

Suspected non-convulsive status
Non traumatic encephalopathy
Coma of unknown cause

Elective standard EEG if:

Strong suspicion of epilepsy (to support classification)
Developmental or language regression

NOT generally after a first afebrile seizure or febrile seizures

25
Q

What aspects of a seizure do you parents need to be counselled on?

A

Counselling on recurrence risk of fever related seizures and risk of epilepsy.
First aid training and what not to do in a convulsive seizure (especially not to put something into the child’s mouth or do chest compressions)
They maybe considered for training to administer rescue medication, buccal midazolam for example, at 5 minutes.
Need to be aware of when to call an ambulance (e.g. after 5 minutes of a convulsive seizure, or if rescue medication was ineffective after 5 minutes)
Follow up arrangements, by either their Consultant, or a referral to an epilepsy specialist

26
Q

What is the significance of early hand preference?

A

Early hand preference before 12 months have a higher risk of hemiplegia of the non-dominant side

27
Q

What are the possible causes of delayed walking?

A

Central causes: delayed maturation (constitutional); global developmental causes (e.g. genetic/chromosomal disorders with often hypotonia or dysmorphism); all causes of hemiplegia often with hypertonia including cerebral palsy

Peripheral: spinabifida

Muscular and neuromuscular diseases: such as Duchenne Muscular dystrophy

Enviromental: bottom shufflers, institutionalised (chronically ill, prematurity, gross pycho-social deprivation)

Orthopaedic: developmental dysplasia of the hip

Metabolic/hormonal: Hypothyroidism, rickets, mucopolysaccharidosis

28
Q

What is Sturge-Weber syndrome?

A

Rare disorder characterized by the association of a facial birthmark- port-wine birthmark
Neurological abnormalities
Eye abnormalities such as glaucoma

29
Q

What is Todd’s paralysis?

A

Experienced by peple with epilepsy,
Seizure is followed by a brief period of temporary paralysis
Paralysis may be partial or complete but usually occurs on just one side of the body