Synapses and memory Flashcards
What are the types of learning?
Nondeclarative (procedural) and declarative (semantic, episodic)
who first proposed the idea that the site of contact between neurons could play a role in memory formation
Santiago Ramon y Cajal
What is habituation?
Response weakens with repeated stimulus presentation due to repetition but not due to adaptation of senses or fatigue. Not an extinction of associations acquired through learning.
What is dishabituation
The repeated tactile stimulation of the siphon leads to a reduced gill withdrawal response. The response is reinstated after stimulation by a different stimulus
What is presynaptic depression?
a form of synaptic plasticity
what does short-term habituation cause
gill withdrawal from the motoneuron
what does long-term habituation refers to
retraction of some of the synaptic terminals from the sensory neurons onto the motoneurons
The dynamics of signal transmission can be altered by changing what?
synapse efficacy over time
What are the three main pathways to the hippocampus?
- perforant pathway
- mossy fibre pathway
- schaffer collateral pathway
What is the perforant pathway?
input from entorhinal cortex
what is the mossy fibre pathway?
dentate gyrus to CA3 pyramidal cells
what is the schaffer collateral pathway
CA3 to CA1 pyramidal cells
When do AMPA receptors open?
if glutamate binds to them
What are NMDA receptors both?
Ligand and voltage gated
When do NMDA receptors open?
- Binding of glutamate
2. Membrane depolarizes above threshold expelling the Mg2+ plug
