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Neuroscience Y1/T1 > Synaptic Transmittion > Flashcards

Synaptic Transmittion Flashcards

1
Q

EPSP mean?

A

Excitatory post synaptic potential

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2
Q

Useful way of visualising action potentials and synapses

A

Think in terms of voltage on a graph- IPSP moves voltage further away from threshold

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3
Q

5 steps of transmitter release

A
  1. Most vesicles docked by SNARE proteins
  2. Action potential causes V-gated Ca2+ channels to open
  3. Ca2+ floods in
  4. Ca2+ binds to synaptotagmin- vesicles fuses with membrane
  5. Completely fuses, releasing transmitter
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4
Q

Define Quantal release

A

Transmitter released by a single vesicles

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5
Q

Two ways of terminating transmitter

A

Breakdown: enzyme breakdown

Removal: glial cells (Astoctyes) can uptake from cleft then breakdown

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Neuroscience Y1/T1 (10 decks)

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