synovial Flashcards

(50 cards)

1
Q

Sterile heparinized tube

A

gram’s stain and culture

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2
Q

Heparin or EDTA

A

cell count

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3
Q

sodium fluoride tube

A

glucose analysis

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4
Q

Deeper yellow

A

Inflammatory & noninflammatory
effusions

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5
Q

Green

A

bacterial infection

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6
Q

red

A

Hemorrhagic arthritis

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7
Q

synovial is turbid

A

Presence of WBC, Synovial cells debris and
fibrin

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8
Q

synovial is milky

A

presence of crystals

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9
Q

viscosity is caused by

A

hyaluronic acid

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10
Q

it affects the production of hyaluronidase

A

arthritis

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11
Q

diluting fluid for cell count

A

0.3% normal saline solution

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12
Q

performed on cytocentrifuged preparations or on
thinly smeared slides.

A

differential count

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13
Q

Increased neutrophils indicate

A

septic condition

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14
Q

lymphocytes suggests

A

nonseptic inflammation

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15
Q

Primary Cell can be seen in Normal Synovial Fluid

A

Mononuclear cells
Monocytes
Macrophages
Synovial tissue

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16
Q

significance of neutrophil

A

bacterial sepsis
crystal induced inflammation

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17
Q

significance of lymphocytes

A

non-septic inflammation

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18
Q

significance of macrophage

A

normal
viral infection

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19
Q

significance of synovial lining cell

A

normal

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20
Q

significance of LE cell

A

lupus erythematosus

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21
Q

significance of reiter cell

A

reiter syndrome
non-septic inflammaton

22
Q

significance of RA cell

A

rheumatoid arthritis
immunologic inflammation

23
Q

significance of cartilage cell

A

osteoarthritis

24
Q

significance of rice bodies

A

tuberculosis
septic
rheumatoid arthritis

25
significance of fat droplets
traumatic injury chronic inflammation
26
resembling mesothelial
synovial lining cell
27
neutrophil containing round body
LE cell
28
vacuolated macrophage ingested neutrophils
reiter cell
29
An important diagnostic test in the evaluation of arthritis
crystal identification
30
Causes of of Crystal formation
Metabolic Disorders Decreased renal excretion Degeneration of cartilage and bone Injection of Medications such as corticosteroids
31
monosodium significance and shape
gout needle
32
calcium pyrophosphate significance and shape
pseudogout rhombic square, rods
33
cholesterol significance and shape
extracellular notched, rhombic plates
34
corticosteroid significance and shape
injection flat, variable-shaped plates
35
calcium oxalate significance and shape
renal dialysis envelope
36
apatite or calcium phosphate
osteoarthritis small particles require electron microscope
37
run parallel to the long axis of the crystal
MSU crystals
38
much quicker, producing a blue color and positive birefringence.
CPPD crystals
39
produces a yellow color
MSU crystals
40
run perpendicular to the long axis of the crystal
CPPD crystals
41
Provides rapid differentiation between inflammatory and septic arthritic
lactate test
42
normal synovial values volume color clarity viscosity WBC ct neutrophils crystals glucose:plasma total protein
<3.5 ml colorless to pale yellow clear able to form a string 4-6 cm long <200 cells/uL <25% none present <10 mg/dl lower than blood glucose level < 3 g/dl
43
The common organisms that infect synovial fluid are the fastidious
Haemophilus species and Neisseria gonorrhoeae
44
autoimmune diseases that cause very serious inflammation of the joints and are diagnosed in the serology laboratory by demonstrating the presence of their particular autoantibodies in the patient’s serum
rheumatoid arthritis and lupus erythematosus
45
demonstration of antibodies to the causative agent _______ in the patient’s serum can confirm the cause of the arthritis.
Borrelia burgdorferi
46
Non-inflammatory color & clarity: viscosity: WBC: neutrophils: glucose:
- clear and yellow - good viscosity - < 1000 uL - < 30% - normal glucose
47
Inflammatory: immunologic origin color & clarity: viscosity: WBC: neutrophils: glucose:
color & clarity: cloudy, yellow fluid viscosity: poor viscosity WBC: 2000 - 75,000 uL neutrophils: > 50% glucose: decrease glucose presence of autoantibodies
48
Inflammatory: crystal induced origin color & clarity: viscosity: WBC: neutrophils: glucose:
color & clarity: cloudy or milky fluid viscosity: low viscosity WBC: up to 100,000 uL neutrophils: <70% glucose: decrease glucose crystal present
49
Septic color & clarity: viscosity: WBC: neutrophils: glucose:
color & clarity: cloudy, yellow green fluid viscosity: variable viscosity WBC: 50,000 - 150,000 uL neutrophils: > 75% glucose: decrease glucose positive culture and gram stain
50
hemorrhagic color & clarity: viscosity: WBC: neutrophils: glucose:
color & clarity: cloudy, red fluid viscosity: low viscosity WBC: equal to blood neutrophils: equal to blood glucose: equal to blood