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Flashcards in Systemic factors Deck (46):
1

what factors do we know of that cause periodontal disease

host immune response, local and systemic factors, and bacterial plaque

2

what are contributing systemic risk factors

conditions, habits, or disease that increase an individuals susceptibility to periodontal infection

3

system factors ____ or ______ the host response

modifies or amplifies

4

what is the number one factor that most affects progression of perio

tobacco

5

what are a few systemic risk factors?

1. tobacco use
2. diabetes
3. ostoporosis
4. hormone alterations
5. AIDS
6. leukemia
7. obesity
8. genetics

6

what are the three types of diabetes

1. type 1-insulin dependent
2. type 2-non-insulin dependent
3. gestational-occurs during pregnancy

7

individuals with ____ or ____ diabetes are more likely to have perio disease than people without disease

un-diagnosed or uncontrolled

8

T/F: patients with well-controlled diabetes have a better chance of perio disease than persons without diabetes

False: the risk is the same

9

perio disease is considered the ___ complication of unctrolled diabetes

6th

10

people with uncontrolled or poorly controlled blood glucose levels have an increased risk for developing what?

1. acute periodontal abcesses
2. bone loss
3. more sugar in gingival crevicular fluid

11

what effects does poorly controlled diabetes have on the periodontium?

1. reduced PMN function and defective chemotaxis
2. Higher levels of PGE2
3. AGE (excessive formation of accumulated glycation end products)

12

characteristics of AGE

1. derived from reaction of glucose and proteins
2. collagen is less likely to be repaired or made
3. AGE may contribute to chronic health complications

13

oral signs of diabetes

1. xerostomia
2. burning tongue
3. present with periodontal abscesses

14

is diabetes well controlled if the blood glucose levels are stabilized within the recommended range?

yes

15

what is leukemia

cancer of the blood forming tissue

16

oral manifestations of leukemia

ulcerations, palatal petechiae, fiery red gingival tissues

17

define NUG and NUP

NUG: tissue necrosis limited to gingiva
NUP: usually an indication of severe immune suppression

18

what is LGE? response to periodontal instrumentation?

Linear Gingival Erthema: 2-3 mm red band along gingival margin
-does NOT response to perio instrumentation and daily oral hygiene

19

what species is associated with LGE

candida

20

LGE has reduced ____ and ____ and increased numbers of IgG plasma cells and PMNs

T-cells and macrophages

21

T/F: osteoporosis initates tissue destruction and aggravate the progression of perio disease

False: it does not initiate tissue destruction

22

when can changes in hormone alterations occur?

-puberty
-pregnancy
-menopause
-birth control pill

23

increased in hormones causes ____ blood circulation to gingival tissues

increased

24

puberty has an association with what?

serum levels of testosterone, estrogen, and progesterone and prevotella intermedia, P nigrescens and capnocytophaga species which causes increased bleeding and inflammation

25

is it possbile for pre-existing gingivations to cause increased inflammation during menstruation?

yes

26

when is progesterone highest?

before menstruation

27

exaggerated response to ____ amounts of plaque during pregnancy. what patients does this occur in?

small
-occurs in patients who have gingivitis before becoming pregnant

28

liklihood of gingivitis increases in ____ month when circulating hormones related to pregnancy increase in bloodstream

2nd month

29

incidence of gingivitis is highest in ___ month when circulating hormones peak

8th month

30

prevotella intermedia causes elevated levels of what, suppresses what, and what is depressed?

-elevated progesterone and estrogen levels
-suppresses immune response
-No PMN and chemotaxis and phagocytes depressed

31

what is pyogenic granuloma?

pregnancy tumor

32

does the pregnancy tumor go away after baby is born?

yes

33

when is it safest to treat someone who is pregnant?

2nd trimester

34

is it possible for the oral bacteria to be passed cross the placenta and harm the fetus?

yes

35

T/F: pregnant women with periodontal disease are not as likely to have a premature delivery

false they are 7 times more likely to have a premature baby

36

____ plays a role in periodontal inflammation and in regulating onset of labor

prostaglandin E2

37

research shows that there is no relationship with _____ being used today and increased gingivitis

low dose contraceptive

38

should women with aggressive periodontitist take the pill?why?

no because it might lead to more advanced disease

39

individuals with defective PMN production have increased susceptibility to recurrent bacterial infections such as:

1. oral ulcerations
2. gingivitis
3. periodontitist

40

T/F: Il-1-genotype is a stronger risk factor than smoking

False. smoking is

41

xerostomia can cause?

1. oral candadiasis
2. root surface caries
3. excess plaque

42

drugs with xeriostomia effects?

1. antihypertensives
2. narcotic analgescis
3. diuretics
4. tranquilizers
5. sedatives
6. antimetabolites

43

gingival fibroblasts overproduce collagen matrix when stimulated by gingival inflammation. This is side effects of what?

1. anticonsulsants
2. immunosuppressants
3. calcium channel blockers

44

phenytoin effects are commonly seen where?

seen in facial aspect of maxillary

45

examples of drugs for:
1. anticonsultants
2. immunosuppressive
3. calcium channel blocker

1. phenytoin
2. cyclosporine
3. nifedipine

46

can gingival overgrowth be removed? does it come back?

yes with lasers
reoccurs within 1-2 years even in the presence of good plaque control