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PHAR417 > T1-Drugs > Flashcards

T1-Drugs Flashcards

(59 cards)

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1
Q

Acetylcholine

A

cholinergic agonist- muscarinic miosis(pupil constriction) during surgery

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2
Q

carbachol

A

cholinergic agonist- muscarinicmiosis(pupil constriction) during surgery

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3
Q

bethanechol

A

cholinergic agonist- muscarinic. improve poor bladder tone and increase GI motility

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4
Q

methacholine

A

cholinergic agonist- muscarinic. used for asthma test

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5
Q

pilocarpine

A

cholinergic agonist- muscarinic. reduce IOP in open angle glaucoma

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6
Q

cevimeline

A

cholinergic agonist- muscarinic. dry mouth

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7
Q

chantix

A

cholinergic agonist- nicotinic. stop smoking

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8
Q

atropine

A

selective muscarinic antagonist: mydriases(dilate iris) and thicken lens.

  • decrease mucosal secretion
  • increase BP
  • increase HR
  • overactive bladder
  • muscarinic agent or cholinesterase inhibitor poisoning treatment
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9
Q

hyoscyamine

A

selective muscarinic antagonist

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10
Q

ipratropium

A

selective muscarinic antagonist: bronchodilation in asthma

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11
Q

tiotropium (spiriva)

A

selective muscarinic antagonist:

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12
Q

tolterodine (detrol)

A

selective muscarinic antagonist: urinary urgency

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13
Q

oxybutynin

A

selective muscarinic antagonist: urinary urgency

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14
Q

solifenacin (vesicare)

A

selective muscarinic antagonist: urinary urgency

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15
Q

benztropine (cogentin)

A

selective muscarinic antagonist: parkinsons

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16
Q

scopolamine

A

selective muscarinic antagonist:

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17
Q

glycopyrrolate

A

selective muscarinic antagonist

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18
Q

darifenacin (enablex)

A

selective muscarinic antagonist

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19
Q

cyclopentolate

A

selective muscarinic antagonist

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20
Q

amitriptyline

A

nonselective muscarinic antagonist

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21
Q

dicyclomine

A

nonselective muscarinic antagonist

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22
Q

benadryl

A

nonselective muscarinic antagonist

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23
Q

ambenonium

A

cholinesterase inhibitor

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24
Q

demecarium

Study These Flashcards
A

cholinesterase inhibitor

25
donepezil
cholinesterase inhibitor
26
echothiophate
irreversible cholinesterase inhibitor. treats glaucoma
27
galantamine
cholinesterase inhibitor
28
malathione
irreversible cholinesterase inhibitor
29
DFP
irreversible cholinesterase inhibitor for glaucoma
30
neostigmine
semi reversible cholinesterase inhibitor for glaucoma, and MG therapy
31
physostigmine
reversible cholinesterase inhibitor for glaucoma and atropine toxicity
32
pyridostigmine
semi reversible cholinesterase inhibitor for MG
33
rivastigmine (exelon)
cholinesterase inhibitor
34
tacrine
cholinesterase inhibitor
35
edrophonium (tensilon)
reversible cholinesterase inhibitor for diagnosing and dose assessment of MG
36
soman
irreversible cholinesterase inhibitor
37
tabun
irreversible cholinesterase inhibitor
38
pralidoxime (2-PAM)
cholinesterase regenerator
39
atracurium
non depolarizing nicotinic antagonist
40
doxacurium
non depolarizing nicotinic antagonist
41
mivacurium
non depolarizing nicotinic antagonist
42
pancuronium
non depolarizing nicotinic antagonist
43
rocuronium
non depolarizing nicotinic antagonist
44
tubocurarine
non depolarizing nicotinic antagonist
45
dantrolene
non depolarizing nicotinic antagonist
46
d-tubocurarine
non depolarizing nicotinic antagonist
47
vencuronium
non depolarizing nicotinic antagonist
48
succinylcholine
depolarizing nicotinic antagonist
49
decamethonium
depolarizing nicotinic antagonist
50
general receptor effects of cholinergic agonist
- decrease HR and BP - increase GI motility - pupil constriction - increase secretion - bronchial constriction
51
general receptor effects muscarinic antagonists :CNS
-increase vagal nerve activity
52
general receptor effects muscarinic antagonist: cardio
- decrease HR initially b/c of vagal nerve stimulation. eventually blocking of M2 receptors cause an increase in BP
53
general receptor effects muscarinic antagonist: respiratory
-bronchodilation
54
general receptor effects muscarinic antagonist: GI
- decrease in: | salivation, gastric secretion, and GI motility
55
general receptor effects muscarinic antagonist: urinary
urine retention (relaxed ureter and bladder smooth muscle)
56
general receptor effects muscarinic antagonist: sweating
atropine fever
57
general receptor effects cholinesterase
- decrease HR - decrease BP - increase Gi motility - pupil constriction - increase then decrease in IOP - increase in secretions - bronchial constriction
58
general receptor effects depolarizing nicotinic antagonist
- activation receptors to cause Na influx, causing partial depolarization and contraction. - when Ach activates the receptor further, flaccid paralysis can occur - the partially depolarized motor end plate results in inactive nicotinic channels and Ach cannot repolarize
59
general receptor effects non depolarizing nicotinic antagonist
- 2 Ach binds to nicotinic receptor to activate. if 1 is antagonist, the activity is decreased - can be reversed by cholinesterase inhibitors

PHAR417 (10 decks)

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