Table 20.5

Question 1

Postinfectious Glomerulonephritis frequently presents as which condition

Answer 1

Nephritic

Question 2

What is the pathogenesis of Postinfectious Glomerulonephritis

Answer 2

Immune comple mediated, circulating or planted antigen

Question 3

Which condition will present the diffuse endocapillary proliferation with leukocytosis infiltration on light microscopy

Answer 3

Postinfectious Glomerulonephritis

Question 4

Which condition with sho Granular IgG and C3 in the GBM and mesangium, with the occasional IgA on fluorescence microscopy

Answer 4

Postinfectious Glomerulonephritis

Question 5

How will Postinfectious Glomerulonephritis present with electron microscopy

Answer 5

Primary with subepithelial humps and deposits early in the disease

Question 6

Goodpasture syndrome will frequently present with which clinical feature

Answer 6

RPGN

Question 7

What is the pathogenesis of Goodpasture syndrome

Answer 7

Anti GBM COL4-A3 antigen

Question 8

Which condition will present as extracapillary proliferation with crescents and necrosis on light microscopy

Answer 8

Goodpasture syndrome

Question 9

Which condition will present with Linear IgG and C3 with fibrin in crescents under fluorescence microscopy

Answer 9

Goodpasture syndrome

Question 10

Membranous nephropathy will typically present with which clincal presentation

Answer 10

Nephrotic syndrome

Question 11

What is the pathogenesis of Membranous nephropathy

Answer 11

In situ immune complex formation, with PLA2Rantigen for most cases

Question 12

Which condition will present with with diffuse capillary wall thickening under light microscopy

Answer 12

Membranous nephropathy

Question 13

Which condition with present with granular IgG and C3 diffusely under fluorescence microscopy

Answer 13

Membranous nephropathy

Question 14

Minimal change disease will commonly present with which clinical presentation

Answer 14

Nephrotic syndrome

Question 15

What condition will present with normal findings with some lipid in the tubules under light microscopy

Answer 15

Minimal change disease

Question 16

What is the presentation of Minimal change disease under fluorescence microscopy

Answer 16

None

Question 17

What is the presentation of Minimal change disease under EM

Answer 17

-Loss of foot processes with no deposits

Question 18

Focal segmental glomerulosclerosis normally presents as which clinical presentation

Answer 18

Nephrotic syndrome

Question 19

What is the pathogenesis of Focal segmental glomerulosclerosis

Answer 19

-Ablation nephropathy

Question 20

What condition presents as focal and segmental sclerosis and hyalinosis

Answer 20

Focal segmental glomerulosclerosis

Question 21

What conditions presents as focal IgM and C3 under fluorescence microscopy

Answer 21

Focal segmental glomerulosclerosis

Question 22

How does Focal segmental glomerulosclerosis present under EM

Answer 22

Loss of foot processes with epithelial denudation

Question 23

Membranoproliferative glomerulonephritis type 1 normally presents with which clinical feature

Answer 23

Nephrotic/nephritic syndome

Question 24

What is the pathogenesis of Membranoproliferative glomerulonephritis type 1

Answer 24

Immune complexes

Question 25

Which conditions presents with mesangial or membranoproliferation

Answer 25

Membranoproliferative glomerulonephritis type 1

Question 26

What condition will have IgG, C3, C1q, C4 under fluorescence microscopy

Answer 26

Membranoproliferative glomerulonephritis type 1

Question 27

Membranoproliferative glomerulonephritis type 2 will typically present with which clinical feature

Answer 27

Hematuria and chronic renal failure

Question 28

What is the pathogenesis of Membranoproliferative glomerulonephritis type 2

Answer 28

-Autoantibody, alternative complement pathway

Question 29

Which condition will present with mesangial proliferation with GBM splitting

Answer 29

Membranoproliferative glomerulonephritis type 2 aka dense deposit disease

Question 30

Which condition will present with C3 but no C1q or C4 under fluorescence microscopy

Answer 30

Membranoproliferative glomerulonephritis type 2, and dense deposit

Question 31

IgA nephropathy will typically present with which clinical feature

Answer 31

Recurrent hematuria and proteinuria

Question 32

Which condition will present with focal mesangial proliferative glomerulonephritis with mesangial widening

Answer 32

IgA nephropathy

Question 33

Which condition will Preston with IgA, IgG, IgM and C3 in the mesangium

Answer 33

IgA nephropathy