Table 20.5 Flashcards Preview

Robbins Pathology Renal (Chaptr 20,21) > Table 20.5 > Flashcards

Flashcards in Table 20.5 Deck (33)
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1

Postinfectious Glomerulonephritis frequently presents as which condition

Nephritic

2

What is the pathogenesis of Postinfectious Glomerulonephritis

Immune comple mediated, circulating or planted antigen

3

Which condition will present the diffuse endocapillary proliferation with leukocytosis infiltration on light microscopy

Postinfectious Glomerulonephritis

4

Which condition with sho Granular IgG and C3 in the GBM and mesangium, with the occasional IgA on fluorescence microscopy

Postinfectious Glomerulonephritis

5

How will Postinfectious Glomerulonephritis present with electron microscopy

Primary with subepithelial humps and deposits early in the disease

6

Goodpasture syndrome will frequently present with which clinical feature

RPGN

7

What is the pathogenesis of Goodpasture syndrome

Anti GBM COL4-A3 antigen

8

Which condition will present as extracapillary proliferation with crescents and necrosis on light microscopy

Goodpasture syndrome

9

Which condition will present with Linear IgG and C3 with fibrin in crescents under fluorescence microscopy

Goodpasture syndrome

10

Membranous nephropathy will typically present with which clincal presentation

Nephrotic syndrome

11

What is the pathogenesis of Membranous nephropathy

In situ immune complex formation, with PLA2Rantigen for most cases

12

Which condition will present with with diffuse capillary wall thickening under light microscopy

Membranous nephropathy

13

Which condition with present with granular IgG and C3 diffusely under fluorescence microscopy

Membranous nephropathy

14

Minimal change disease will commonly present with which clinical presentation

Nephrotic syndrome

15

What condition will present with normal findings with some lipid in the tubules under light microscopy

Minimal change disease

16

What is the presentation of Minimal change disease under fluorescence microscopy

None

17

What is the presentation of Minimal change disease under EM

-Loss of foot processes with no deposits

18

Focal segmental glomerulosclerosis normally presents as which clinical presentation

Nephrotic syndrome

19

What is the pathogenesis of Focal segmental glomerulosclerosis

-Ablation nephropathy

20

What condition presents as focal and segmental sclerosis and hyalinosis

Focal segmental glomerulosclerosis

21

What conditions presents as focal IgM and C3 under fluorescence microscopy

Focal segmental glomerulosclerosis

22

How does Focal segmental glomerulosclerosis present under EM

Loss of foot processes with epithelial denudation

23

Membranoproliferative glomerulonephritis type 1 normally presents with which clinical feature

Nephrotic/nephritic syndome

24

What is the pathogenesis of Membranoproliferative glomerulonephritis type 1

Immune complexes

25

Which conditions presents with mesangial or membranoproliferation

Membranoproliferative glomerulonephritis type 1

26

What condition will have IgG, C3, C1q, C4 under fluorescence microscopy

Membranoproliferative glomerulonephritis type 1

27

Membranoproliferative glomerulonephritis type 2 will typically present with which clinical feature

Hematuria and chronic renal failure

28

What is the pathogenesis of Membranoproliferative glomerulonephritis type 2

-Autoantibody, alternative complement pathway

29

Which condition will present with mesangial proliferation with GBM splitting

Membranoproliferative glomerulonephritis type 2 aka dense deposit disease

30

Which condition will present with C3 but no C1q or C4 under fluorescence microscopy

Membranoproliferative glomerulonephritis type 2, and dense deposit