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Prudent use of Antimicrobials > Table- entrance > Flashcards

Table- entrance Flashcards

(75 cards)

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1
Q

Penicillins- Narrow spectrum

A

benzylpenicillin- Na, K
benzylpenicillin-benzathine
phenoxymethyl-penicillin

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2
Q

Penicillins-Penicillinase stable

A

oxacillin
cloxacillin
diclocloxacillin
flucloxacillin

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3
Q

Penicillins- broad spectrum

A

amoxicillin

ampicillin

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4
Q

Penicillins- Pseudomonas acting

A

ticarcillin

piperacilin

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5
Q

Penicillins: mode of action and mechanism of action

A

Time dependent Bactericidal

Inhibit cell wall synthesis

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6
Q

Beta lactamase inhibitors

A

Clavulinic acid
Sulbactam
Tazobactam

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7
Q

Cephalosporins: 1st generation

A

Cephazoline
Cephapirin
Cephalexin
Cefadroxil

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8
Q

Cephalosporin: 2nd generation

A

Cefuroxime

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9
Q

Cephalosporin: 3rd generation

A 
Ceftiofur
Cefovecin
Cefotaxime
Ceftazidime
Cefoperazone
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10
Q

Cephalosporin: 4th generation

A

Cefquinome

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11
Q

Cephalosporines: mode of action and mechanism of action

A

Time dependent Bactericidal

Inhibit cell wall synthesis

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12
Q

Carbapenams

A

imipenem

meropenem

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13
Q

Carbapenams: mode of action and mechanism of action

A

Time dependent Bactericidal

Inhibit cell wall synthesis

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14
Q

Monobactams

A

Aztreonan

Tigemonam

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15
Q

Monobactams: mode of action and mechanism of action

A

Time dependent Bactericidal

Inhibit cell wall synthesis

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16
Q

Beta lactams antibiotics

A 
Penicillins
beta lactamase inhibitors
cephalosporines
carbapenams
monobactams
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17
Q

Aminoglycosides

A 
Streptomycin
Neomycin
Paromycin
Kanamycin
Gentamycin
Tobramycin
Amikacin
Apramycin
Spectinomycin (bacteriostatic)
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18
Q

Aminoglycoside: mode of action

A

Conc. Dependent bactericidal (except spectinomycin which is bacteriostatic)

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19
Q

Aminoglycoside: mechanism of action

A

Inhibit protein synthesis (30s subunit), mistranslation

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20
Q

Tetracyclines: Short acting

A

Chlorotetracycline
Oxytetracycline
Tetracycline

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21
Q

Tetracyclines: long acting

A

Doxycycline

Minocycline

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22
Q

Tetracyclines: mode of action

A

Bacteriostatic

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23
Q

Tetracyclines: mechanism of action

A

Inhibit protein synthesis (30s subunit)

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24
Q

Macrolides

A 
Erythromycin
Azithromycin
Clarithromycin
Spiramycin
Tylosin
Tylvalosin
Tilmicosin
Tulathromycin
Gamithromycin
Tildipirosin
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25
Macrolides: mode of action
Bacteriostatic
26
Macrolides: mechanism of action
Inhibition of protein synthesis (50s subunit)
27
Lincosamides
Lincomycin | Clindamycin
28
Lincosamides: mode of action
Bacteriostatic
29
Lincosamides: Mechanism of action
Inhibition of protein synthesis (50s subunit)
30
Pleuromutilins
Tiamulin | Valnemulin
31
Pleuromutilins: mode of action
Bacteriostatic
32
Pleuromutilins: mechanism of action
Inhibition of protein synthesis (50s subunit)
33
Phenicols
Chloramphenicol Florfenicol Thiamphenicol
34
Phenicol: mode of action
Bacteriostatic
35
Phenicol: mechanism of action
Inhibition of protein synthesis (50s subunit)
36
Peptide AB: Polypeptide
Bacitracin Polymxin B Polymyxin E= colistin
37
Peptide: Glycopeptide AB
Vancomycin | Teicoplanin
38
Peptide AB: Polypeptide: mode of action
Conc. dependent, Bactericidal
39
Peptide AB: Polypeptide: mechanism of action
They act like a cationic detergent
40
Peptide: Glycopeptide AB: mode of action
Time dependent, bactericidal
41
Peptide: Glycopeptide AB: mechanism of action
Inhibit cell wall synthesis
42
Rifamycins
Rifampicin
43
Rifamycin: mode of action
time dependent, bactericidal
44
rifamycin: mechanism of action
inhibit bacterial DNA- dependent RNA polymerase
45
Pseudomonic acid
Mupirocin
46
Pseudomonic acid: mode of action
bactericidal
47
Pseudomonic acid: mechanism of action
inhibit cell wall synthesis
48
Phosphoric acid
Fosfomycin
49
Phosphoric acid: mode of action
Bactericidal
50
Phosphoric acid: mechanism of action
Inhibit cell wall synthesis
51
Fusidic acid
fusidic acid
52
Fusidic acid: mode of action
Bacteriostatic
53
Fusidic acid: mechanism of action
Inhibit protein synthesis
54
Sulphonamides
``` Sulfadimidine Sulfadiazine Sulfachlorpyrazine Sulfachlorpyrdazine Sulfamethoxasole Sulfadoxine Sulfaquinoxaline Sulfasalazine ```
55
Sulphonamide: mode of action
Separately bacteriostatic and when combined time dependent bactericidal
56
Sulphonamide: mechanism of action
Inhibition of folic acid synthesis (PABA)
57
Diaminopyrimidines
Trimethoprim | Baquiloprim
58
Diaminopyrimidines: mode of action
Separately bacteriostatic and when combined time dependent bactericidal
59
Diaminopyrimidines: mechanism of action
Inhibition of folic acid synthesis (PABA)
60
Fluoroquinolines: 1st generation
Nalidixic acid
61
Fluoroquinolines: 2nd generation
``` Fumequin Norflaxacin Orbifloxacin Ciprofloxacin Enrofloxacin Danofloxacin Diflofloxacin Marbofloxacin ```
62
Fluorquinolines: 3rd generation
Levofloxacin | Sparofloxacin
63
Fluoroquinolines: 4th generation
Pradofloxacin | Moxifloxacin
64
Fluorquinolin: mode of action
Conc. dependent Bactericidal
65
Fluoroquinoline: mechanism of action
Inhibit DNA synthesis
66
Nitrfurans
Nitrofurantoin | Furazolidine
67
Nitrofuran: mode of action
Bactericidal
68
Nitrofurans: mechanism of action
Destroy DNA of bacteria
69
Nitrimidazoles
Metronidazole Ronidazole Tinidaazole
70
Nitroimidazoles: mode of action
Conc. dependent Bactericidal
71
Nitroimidazoles: Mechanism of action
Destroy DNA of bacteria
72
Conc. dep. Bactericidal
Fluoroquinolines Polypeptides Colistin Aminoglycosides (spectinomycin:bacteriostatic)
73
Time dep. Bactericidal
``` Penicillin Cephalosporin carbapenams monobactams glycopeptide Potentiated sulphonamide Rifamycines ```
74
Bacteriostatic
``` Tetracycline macrolide phenicols lincosamides pleuromutilins fusidic acid sulphonamides+diaminopyrimidine when alone ```
75
Beta lactamase group
Penicillins Beta-lactamase inhibitors Cephalosporins carbapenems Monobactams

Prudent use of Antimicrobials (4 decks)

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