tablets ppt

Question 1

sugar for palatability; adds 50% to tablet bulk

Answer 1

Sugar-Coated (CT)

Question 2

broken and chewed before ingestion; mannitol (50% of tablet bulk); xylitol (sugar free)

Answer 2

Chewable (CT)

Question 3

coated with a thin layer of a polymer
capable of forming a skinlike film; less bulky

Answer 3

Film-Coated (CT)

Question 4

disintegrate in intestinal fluid; delayed release

Answer 4

Enteric-Coated (CT)

Question 5

compressing the fill material more than once

Answer 5

Multiple Compressed Tablet

Question 6

ex. Halazone tablets and KMnO4 tablets for solution

Answer 6

Tablets for Solution

Question 7

compressed granular effervescent salts; Na bicarbonate + citric acid + tartaric acid

Answer 7

Effervescent Tablet

Question 8

dissolved at the buccal/cheeks of the mouth

Answer 8

Buccal Tablet

Question 9

dissolved under the tongue

Answer 9

Sublingual

Question 10

aka Compounding Tablets; for extemporaneous compounding, never dispensed as Dosage Form

Answer 10

Dispensing Tablet (MT/TT)

Question 11

no longer used because of the difficulty in achieving sterility

Answer 11

Hypodermic Tablets (MT/TT)

Question 12

aka Vaginal inserts; bullet or ovoid shaped inserted for local or systemic effects

Answer 12

Vaginal Tablet (MT/TT)

Question 13

designed to release their medication with no rate controlling features

Answer 13

Immediate Release

Question 14

have drug release features based on time, course, and/or location

Answer 14

Modified Release

Question 15

aka Controlled Release; release medication over an extended period

Answer 15

Extended Release

Question 16

release at a time other than promptly after administration

Answer 16

Delayed Release

Question 17

2 single doses, one for immediate, another for delayed

Answer 17

Repeat Action

Question 18

directed towards a region, tissue, or site of absorption

Answer 18

Targeted Release

Question 19

Contains one or more medicinal agents in a flavoured, sweetened base intended to dissolve slowly in the mouth

Answer 19

Lozenges

Question 20

Sugar based lozenges on a stick and contain fentanyl citrate

Answer 20

Lollipops

Question 21

Compressed lozenges; discoid shaped

Answer 21

Troches

Question 22

Molded lozenges ;Softer and has a higher concentration of sugar or gelatin

Answer 22

Pastilles

Question 23

SDF other than suppositories for insertion to body orifices

Answer 23

Inserts

Question 24

Small, sterile SDF containing a concentrated drug for SC implantation where it continuously release the medication over long periods

Answer 24

Implants/Pellets

Question 25

- consider compatibility with excipients - Excipients need compatible with the API

Answer 25

Active Pharmaceutical Ingredients

Question 26

Inert substance added to increase tablet size which is practical for

Answer 26

Diluent/Filler/Bulking Agent

Question 27

diluent compatible to nearly all except avid drugs

Answer 27

Lactose

Question 28

• Imparts cohesiveness to powders causing them to form granules. • Mostly Sticky materials

Answer 28

Binder/Granulators

Question 29

•Facilitates the break up of the tablet when in contact with water/ fluid or in aqueous medium in the GIT.

Answer 29

Disintegrants

Question 30

• Newer class of disintegrants which are effective at much lower levels (2-4%) • Alternative to traditional disintegrants • Has large size

Answer 30

Superdisintegrants

Question 31

• Antifrictionals or Flow Activators (Stop the friction improve the flow properly) • Hydrophobic powders added prior to compression to reduce friction and improve flow properties

Answer 31

Compression Aids

Question 32

Facilitates ejection of tablet from die cavity

Answer 32

Lubricant

Question 33

reduces sticking to the punch or die

Answer 33

Anti-Adherent

Question 34

enhances flow of the granules

Answer 34

Glidants

Question 35

3 roles (glidant, antiadherent, lubricant) - most Common antifrictional

Answer 35

Mg stearate

Question 36

Acidic counterpart of Mg stearate

Answer 36

Stearic Acid

Question 37

Acidic counterpart of Mg stearate

Answer 37

Stearic Acid

Question 38

Water soluble colorants used as a solutions - Organic colorants -FD & C

Answer 38

Dyes

Question 39

Water insoluble colorants that have been absorbed on Hydrous Oxide and used as Dry powders - Use in topical preparations , cosmetics -D & C

Answer 39

Lakes

Question 40

stores materials for compressing

Answer 40

Hopper

Question 41

distributes materials into dies

Answer 41

Feed Frame

Question 42

controls the size and shape of the tablet

Answer 42

Dies

Question 43

compacts materials within the dies (also controls shape)

Answer 43

Punches

Question 44

guide the punches

Answer 44

Cams

Question 45

tablet press that produces about 200 tabs per min

Answer 45

Single-punch press / Eccentric press

Question 46

tablet press that produces over 10,000 tabs per min

Answer 46

Rotary press/multi station press

Question 47

• First step in any manufacturing process • weighing and measuring

Answer 47

Dispensing

Question 48

It is the unit operation in which the size of solid pieces of a material is reduced by the application of mechanical force.

Answer 48

Size Reduction

Question 49

Strain between two surfaces moving in opposite directions or one moving and one stationary producing shearing action. Ex. Colloid Mill

Answer 49

Attrition

Question 50

• Strain is between two or more sharp edged surfaces. • lt is used for fibrous materials as wood and paper Ex. Cutter Mill

Answer 50

Cutting

Question 51

Equipment used in size reduction

Answer 51

Ball Mil Hammer Mill

Question 52

opposes particle fracture and size reduction ceases. In some cases particle agglomeration occurs to such a degree that subsequent milling actually causes size enlargement.

Answer 52

Particle Agglomeration

Question 53

It is a process by which powder particles are removed from a fluid (gases or liquids).

Answer 53

Solid Separation