Tagnawa and Sirmata BSWR (Microbiology-Parasitology) Flashcards
(188 cards)
The steps leading to the synthesis of peptidoglycan occur in the cytoplasm, on the cytoplasmic membrane, and extracellularly. Which antibiotic inhibits an extracellular step in peptidoglycan biosynthesis?
A. Cycloserine
B. Rifampin
C. Penicillin
D. Bacitracin
C. Penicillin
The ability to use compounds and ions other than oxygen as terminal oxidants in respiration is a widespread microbial trait. This capacity is called
A. Photosynthesis
B. Fermentation
C. Anaerobic respiration
D. Nitrogen fixation
C. Anaerobic respiration
The mechanism of the gram stain is based on differences in the cell wall structure of gram-positive and gram-negative bacteria and how each reacts to various reagents. The dyes crystal violet and safranin combine with the cell’s:
A. Cytoplasmic membrane
B. Peptidoglycan
C. Proteins
D. Lipopolysaccharides
B. Peptidoglycan
Obligate anaerobes refer to organisms that
A. Specifically require oxygen as the hydrogen acceptor
B. Can live with or without oxygen
C. Require small amount of oxygen
D. Require a substance other than oxygen as hydrogen acceptor and are sensitive to oxygen inhibition
D. Require a substance other than oxygen as hydrogen acceptor and are sensitive to oxygen inhibition
A sexually active woman came to you for consultation due to foul smelling vaginal discharge. You suspect that this patient has gonococcal infection. To confirm your impression, you intended to do culture of the vaginal discharge. What culture medium will you use?
A. Blood agar
B. Thayer Martin
C.Mac-Conkey agar
D.Chocolate agar
B. Thayer Martin
A 28-year old female, 16 weeks pregnant, who just arrived from Brazil, came in for consult due to trash, arthralgia, conjunctivitis, and fever. She worries about what will happen to her baby. You tell her that:
A. Transplacental transmission does not happen in this disease
B. Drug of choice is Ribavirin but is contraindicated in pregnancy
C. It can infect fetal neuronal tissue leading to microcephaly and neurologic abnormalities
D. There is no screening test available for pregnant women potentially exposed to this infection
C. It can infect fetal neuronal tissue leading to microcephaly and neurologic abnormalities
- the case is Zika Virus
A 12-year old boy from Manila, was admitted due to fever, rash, headache, eye pain, muscle and joint pains for 6 days. The fever subsided on the third day but rose again on the 5th day. His parents mentioned it is his 2nd time to be admitted due to the same symptoms. The first episode occurred last year 2 weeks after a typhoon. What is your impression?
A. Japanese
B. Encephalitis
C. Dengue Fever
B. Zika virus Infection
D. Lassa Fever
C. Dengue Fever
Component of the lipopolysaccharide that is responsible for the symptoms associated with infections such as fever, dilation of blood vessels, shock, and blood clotting:
A. Porin
B. Endotoxin
C. Lipid A
D. Core polysaccharide
C. Lipid A
Period of equilibrium in microbial growth in which new cell numbers are balanced by the death of the cells.
A. Lag Phase
B. Log Phase
C. Stationary Phase
D. Death Phase
C. Stationary Phase
A 25 year old male, medical student goes to the emergency room because of fever, anorexia, nausea for 3 days. He appears jaundiced, with palpable liver and right upper quadrant tenderness. He received Hepatitis B vaccine prior to medical school entrance. You requested for hepatitis serologic tests and came out as follows: anti-HAV IgM (+), anti-HAV IgG (-), HBsAg (-), Anti-HBs (+), antiHBc (-), antiHCV (-). How will you interpret the result?
A. He has Acute Hepatitis A, has vaccine-induced immunity against Hepatitis B, has not been infected with Hepatitis C
B. He has Hepatitis A, Hepatitis B, and Hepatitis C coinfections
C. He has been infected with Hepatitis A and Hepatitis C in the past, and has Hepatitis B now
D. The result is inconclusive
A. He has Acute Hepatitis A, has vaccine-induced immunity against Hepatitis B, has not been infected with Hepatitis C
Which of the following serologic patterns is suggestive of a patient with chronic hepatitis B with high level of viral replication and greater infectivity to intimate contacts?
A. HBsAg (+), anti-HBs (-), anti-HBc (+), HBeAg (+), HBV DNA (+)
B. HBsAg (-), anti-HBs (-), anti-HBc (+), HBeAg (+), HBV DNA (+)
C. HBsAg (+), anti-HBs (-), anti HBc (-), HBeAg (-), HBV DNA (+)
D. HBsAg (+), anti-HBs (+), anti-HBc (+), HBeAg (+), HBV DNA (+)
A. HBsAg (+), anti-HBs (-), anti-HBc (+), HBeAg (+), HBV DNA (+)
A pregnant woman was reactive for HBsAg. An HBV DNA requested was high, more than 200 000 IU/ml. The patient worries about what will happen to her baby. What will you tell the patient?
A. There is a low risk of maternal-to-child transmission
B. Treatment is contraindicated in pregnant patients
C. The pregnant patient should be initiated with antiviral treatment on 28-32 weeks AOG to minimize the chance of newborn infection
D. The baby already acquired lifelong immunity
C. The pregnant patient should be initiated with antiviral treatment on 28-32 weeks AOG to minimize the chance of newborn infection
A surgical instrument was contaminated by a spore forming bacteria. Which of the following biocides can be used to sterilize the object?
A. Ionizing radiation
B. UV
C. Ethanol 40%
D. Triclosan
A. Ionizing radiation
Mac Conkey agar is a differential culture medium that contains a specific substrate and neutral red as an indicator. This agar is used to differentiate
A. Lactose fermenters from non-lactose fermenters
B. Glucose fermenters from sucrose fermenters
C. Sucrose fermenters from non-sucrose fermenters
D. Halophiles from non-halophiles
A. Lactose fermenters from non-lactose fermenters
Test that detect virus or antigen on infected cell, except?
A. ELISA
B. Radioimmunoassay
C. Electrophoresis
D. Latex agglutination
C. Electrophoresis
Test that confirms seroconversion or/and infection with HIV.
A. Western Blot
B. Southern Blot
C. Northern Blot
D. All of the above
A. Western Blot
Heterophile antibody is seen in
A. CMV
B. EBV
C. Varicella
D. Herpes
B. EBV
Koplik spot :
A. Measles
B. German Measles
C. HerpesVirus
D. Varicella Zoster
A. Measles
A widened mediastinum is a sign of:
a. Consolidated pneumonia
b. Inhalation anthrax
c. Heart attack
d. Food poisoning
b. Inhalation anthrax
Results in worldwide epidemics contributing to emergence epidemics.
A. Dengue
B. Hepatitis B
C. HIV
D. Influenza
D. Influenza
A 60-year-old male came to your clinic presenting with a raised itchy bump on the skin of his hand resembling an insect bite that quickly developed into a painless sore with a black center. Axillary lymph nodes on the same side of the lesion are enlarged as well. What is the most likely causative agent involved?
A. Staphylococcus aureus
B. Streptococcus epidermidis
C. Clostridium perfringens
D. Bacillus anthracis
D. Bacillus anthracis
These viruses establish a state of latent infection in which few if any of viral gene is expressed, except;
A. Varicella
B. EBV
C. HerpesVirus
D. Poliovirus
D. Poliovirus
Third step in viral replication
A. Biosynthesis
B. Attachment
C. Assembly
D. Maturation
A. Biosynthesis
Owl’s eye appearance is seen in
A. HPV
B. VZV
C. CMV
D. EBV
C. CMV