TB Flashcards
(5 cards)
1
Q
What causes TB
A
Mycobacterium tuberculosis
2
Q
Standard treatment
A
Initial: Rifampicin, Isoniazid, Pyrazinamide, Ethambutol - RIPE lasts for 2 months
Continuous phase: Rifampicin + Isoniazid for 4 months
3
Q
Why do we administer pyridoxine hydrochloride during initial phase
A
Should be administered with isoniazid to reduce the occurrence of isoniazid induced neuropathy
4
Q
SE of TB drugs
A
Rifampicin, Isoniazid, Pyrazinamide: Liver toxicity
Isoniazid: Peripheral neuropathy
Ethambutol: Occular toxicity
5
Q
Monitoring TB drugs
A
Drug levels
Visual acutity
Blood counts
Hepatic and renal function
urinalysis
Plasma levels
Auditory function in elderly
