TDM speciment collection and evaluation Flashcards
(8 cards)
1
Q
What specimen is used for TDM?
A
serum, with no gel, plasma, whole blood
2
Q
What state must the patient be in for TDM?
A
Steady state
3
Q
When is trough level drawn?
A
immediately before the next dose
4
Q
When is peak level drawn?
A
1 hr post oral dose, immediately with IV and almost immediately post IM
5
Q
TDM assay used commonly in the clinical lba
A
Immunoassay
6
Q
Reference method for TDM
A
HPLC, HPLC-Mass spec
7
Q
Monoclonal TDM assays
A
target one antigen, usually parent
8
Q
Polyclonal TDM assays
A
target several antigens, parent and metabolities
