teratogen slam a jam

Question 1

ACE i

Answer 1

renal damage

Question 2

aklylating agents

Answer 2

absence of digits

multiple anomalies

Question 3

aminoglycosides

Answer 3

CNVIII toxicity

Question 4

carbamazepine

Answer 4

facial dysmorphism
developmental delay
neural tube defects
phalanx/fingernail dysplasia

Question 5

diethylstilbesterol

Answer 5

vafinal clear cell adenocarcinoma

congenital mulerina/paramesonephric anomales

Question 6

folate antagonists

Answer 6

neural tube defects

Question 7

isotretinoin

Answer 7

multiple seere bith defects

UST HAVE CONTRACEPTIOn

Question 8

litium

Answer 8

ebstien anomaly

Question 9

methimazole

Answer 9

aplasia cutis ongenita

Question 10

phenytoin

Answer 10

fetal hydantoin syndrome: cleft palate, cardiac defects and phalanx/fingernail hypoplasia

Question 11

tetracyclines

Answer 11

discoloured teeth

Question 12

thalidomide

Answer 12

limb defects:
* phocomelia
* micromelia
FLIPPER limbs

Question 13

valproate

Answer 13

inhibition of maternal folate absorption - neural tube defects

Question 14

warfarin

Answer 14

bone deformities
fetal hemorrahge
abortion
ophthalmologic abonromalites

Question 15

list the teratogens that can cause neural tube defects

Answer 15

carbamazepine
folate antagonists
valproate
maternal diabetes

Question 16

list the teratogens that can cause cardiac defects

Answer 16

lithium - ebstein
pheynytoin - cardiac defects
maternal diabetes
vitamin A

Question 17

list the teratogens that can cause hand deformities

Answer 17

alkylating agents - absence of digits
carbamazepine and phenytoin - phalanx/fingernail hypoolasia
thaliomide - phocomelia, micromelia

Question 18

list the effects of OH as a teratogen

Answer 18

common cause od bith defects and inelletula disbaility

Question 19

cocaine

Answer 19

abnormal fetal growth
fetal addiction
placental abruption

Question 20

smoking

Answer 20

low birth weight - leading cause in developed coutnried
preterm labour
placental problems
IUGR 
ADHD

Question 21

what is the leading cause of low birth weight in developed country

Answer 21

smoking

Question 22

iodine lack or excess

Answer 22

congenital goiter or hypothyroidism/cretinism

Question 23

maternal diabetes

Answer 23

caudal regression sydnrome – antal atrsia to sirenomelia (mermaid syndrome)
congenital heart defects
neural tube defects

Question 24

vitamin A excess

Answer 24

extremely high risk for spontaneous abortions (warfarin also can cause abortion)
birth defects - left palate and cardiac)

Question 25

xrays

Answer 25

microcephaly | intellectula disability

Question 26

renal damage

Answer 26

ace inhibitors

Question 27

absence of digits | multiple defects

Answer 27

alkylating agents

Question 28

CNVIII toxicity

Answer 28

aminoglycosides

Question 29

facial dysmorphisms neural tube defects phalanx/fingernail hypoplasia decelopmental delay

Answer 29

carbamazepine

Question 30

vaginal celer cell adenocarcinoma | congenital mullerian anomalies

Answer 30

diethylstilbestrol

Question 31

neural tube defects only

Answer 31

folate antagonists

Question 32

neural tube defects

Answer 32

folate antagonists valproate corbamazepine maternal diabetes

Question 33

multiple severe birth defects

Answer 33

isotretinion

Question 34

ebstine anomaly

Answer 34

lithium

Question 35

aplasia cutis congnita

Answer 35

methimazole

Question 36

what is methimazole

Answer 36

agranulocytosis | blocks perixodase

Question 37

fetal hydantoin syndrome?

Answer 37

cleft palate cardiac defects phalanx/fingernail hyoplasia

Question 38

cleft palate

Answer 38

pheyntoin | viamin a excess

Question 39

what casues cleft palate cardiac defects phlanx/fingernail hypoplasia

Answer 39

fetal hydrantoin syndrome | phenytoin

Question 40

discoloured teeth

Answer 40

tetracyclines

Question 41

limb defets - phocmelia, micromelia, flipper limbs

Answer 41

thalidomide

Question 42

neurla tube defects from inhibiton of maternal folate absorption

Answer 42

valproate

Question 43

bone deformities fetal hemorrhage abortion ophthalmoplegic abnormalities

Answer 43

warfarin

Question 44

abonral fetal growth fetal addiction placental abruption

Answer 44

cocaine

Question 45

``` low birth weight preterm labour placental problems IUGR ADHD ```

Answer 45

smoking

Question 46

congenital goiter or hypothyroidism/creitnism

Answer 46

lack or excess of iodine

Question 47

caudal regression syndomre (ana atreisa to sirenomelia congenital heart defects neural tube defects

Answer 47

maternal diabetes

Question 48

maternal diabetes

Answer 48

caudal regression syndrome - anal astresia to sirenomelia congenital heart defects neural tube defects

Question 49

extremely hig risk for spotnaneous abortions and birth defects: cleft lip and palate

Answer 49

vitamin A excess

Question 50

cleft lip/palate

Answer 50

``` phenytoin (also cardiac defects and phalnz/fingernail hypoplasia) vitamin a (high risk of spontaneous abaortions and birth defects) ```

Question 51

microcephaly | intelletula disabiltiy

Answer 51

xrays