Teratogencity

Question 1

What birth defect is associated with Thalidomide?

Answer 1

Phocomelia

Phocomelia is a congenital condition characterized by malformation of the limbs.

Question 2

What defects are linked to Warfarin exposure during pregnancy?

Answer 2

Nose, Eye, hand defects, and growth retardation

Warfarin can lead to a series of physical abnormalities and developmental issues.

Question 3

Which medication is associated with Cleft lip/palate and microcephaly?

Answer 3

Phenytoin

Phenytoin is an anticonvulsant that can cause various congenital malformations.

Question 4

What is a common defect caused by Finasteride?

Answer 4

Hypospadias and Genital abnormality

Finasteride is used to treat conditions related to androgen levels and can affect male genital development.

Question 5

What effects do Androgens have when used during pregnancy?

Answer 5

Virilization, esophageal, cardiac defects

Androgens can lead to masculinization of female fetuses and other serious defects.

Question 6

What condition can result from Progestins exposure in female fetuses?

Answer 6

Virilization of female fetus

Progestins can cause male-like characteristics in female fetuses.

Question 7

Which drug is linked to the development of vaginal carcinoma?

Answer 7

Stilboestrol

Stilboestrol (diethylstilbestrol) was prescribed to prevent miscarriages but led to significant health issues in female offspring.

Question 8

What are the dental effects associated with Tetracyclines?

Answer 8

Discolored teeth and bone defects

Tetracyclines can lead to permanent discoloration of teeth in children when given during tooth development.