Terminology and Basics Flashcards

1
Q

when does the fertilization age start? how long is the pregnancy?

A

dates pregnancy from the time of fertilization (14 days after the last menstrual period); 38 weeks

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2
Q

when does the menstrual age start? how long is the pregnancy?

A

dates pregnancy from the last menstrual period (LMP); 40 weeks

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3
Q

what are the three ways to determine the embryo/fetus age?

A
  1. measure the gestational sac *chorionic cavity) diameter
  2. Measure the crown rump length (from top of head to bottom of buttock) and compare to a standardized chart
  3. measure the size of the head
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4
Q

What is the length of the embryonic period?

A

from the time of fertilization to 8 weeks

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5
Q

what are the two divisions of the embryonic period?

A
  1. Early development (0-3 wks)

2. Embryonic organogenesis (4-8 wks)

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6
Q

What are the stages of the fertilization age?

A
  1. embryonic period

2. Fetal period

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7
Q

What does the early development sub-period of the embryonic period entail?

A

early embryogeneisis; 0-3 weeks after fertilization (cleavage, gastrulation)

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8
Q

what does the embryonic organogenesis sub-period of the embryonic period entail?

A

neuralation and embryo folding

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9
Q

What is a teratogen?

A

a factor (a drug or environmental toxicant) that causes a birth defects

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10
Q

During which weeks of embryo development is a teratogen most dangerous? when is it least? why?

A

From weeks 0-3 exposure to a teratogen wouldn’t cause deform in the embryo because it would just cause embryonic death;
From weeks 4-8 (organogenosis): exposure to a teratogen causes a HIGH risk of major congenital anomaly (especially weeks 4-6)
From weeks 9-38 (Fetal period): exposure to a teratogen causes functional defects and minor anomalies

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11
Q

When is the fetal period? what features are unique?

A
  • from 9-38 weeks after fertilization
  • organ systems mature and there is RAPID GROWTH
  • environmental factors typically cause only minor defects
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12
Q

What is induction with relation to embryology?

A

a process by which one tissue or group of cells (inducer) produces a signal that changes the fate of an adjacent tissue or set of cell

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13
Q

how many cells are required for induction?

A

2 cells; one that does the inducing, and one that gets induced

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14
Q

Describe the process of differentiation (what is it):

A

process by which a LESS specialized cell becomes MORE specialize;
generates cell diversity

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15
Q

how many cells are need for differentiation?

A

ONE CELL; but gives rise to many other cell types (increases cell diversity)

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16
Q

What is a totipotent cell? give an example

A

a cell that can differentiate into all cell types of the body AND PLACENTAL STRUCTURES
ex: zygote and blastomere

17
Q

What is a pluripotent cell? give an example

A

a cell that is able to differentiate into all cell types of the body (NOT placental structures though!)

  • derived from totipotent cell
    ex: embryonic stem cell
18
Q

what is a multipotent cell? give an example

A

a cell that is able to differentiate into a limited number of cells;
ex: a homepoitic cell = multipotent but can only differentiate in any blood cell (no other tissue)

19
Q

Explain the process of morphogenesis

A

establishment of form and structure; cells become organized into tissues and organs; organs are arranged in specific ways into systems

20
Q

What is cell growth?

A

cell development and REGULATED cell division (mitosis)

21
Q

What is the process of reproduction?

A

process by which new individual organism is produced;

sperm and egg are specialized in this function

22
Q

What percentage of births have major congenital anomalies?

A

4-6% (half recognized at birth; half by age 5)

23
Q

what percentage of births have minor congenital anomalies?

A

15%

24
Q

what is the leading cause of infancy death?

A

birth defects; 21%