TEST 1 Flashcards
(49 cards)
Discuss the management of cardiovascular disease according to new (2013) published guidelines for hypertension, obesity and cholesterol.
ACC/AHA Healthy lifestyle Obesity Cholesterol Risk Assessment
State the primary indication of directics
Its the first line of defense fro hypertension
what blood pressures are appropriate for a direteics
140/90 60 y.o
DM or kidney disease and
What is the mechanism of diuretics
Most common MOA: Block tubular reabsorption of NA which causes sodium to be excreted out with the urine which water will follow
No safe weight loss drugs
effects the cardiovascular system and the kidneys!!!
How do diuretics effect Blood pressure
Decreases blood pressure by,
reducing peripheral resistance
reduce cardiac output
decrease blood volume
What are the ACC/AHA guidelines for good heathy lifestyle
30 min exercise 3-4 days a week
eat lots of fruit and veg
Reduce sodium intake
What are the ACC/AHA guidelines for obesity
team base treatment
weight loss strategies based on BMI
diet and excersise is the best
What is the ACC/AHA guidelines to Cholesterol
Overall health status and risks guide treatment
“Bad cholesterol number” no longer main factor guiding treatment
Decisions for drug treatment based on discussions with healthcare provider
What is the ACC/AHA guidelines for
risk assessment
calculators used to be assessed with a general care docter
risk for african americans for the first time
stoke risks for the first time
what are the ACC/AHA guidelines for blood preasure
systoloic 140/159
diastolic 90/99
if higher life style changes and medications
What happens to most diretics
excreated by kidney tubular secreation
Whats the first choice drug given for hypertension and congestive heart failure
Thiazide
What is the MOA of Thiazide
inhalation of the sodium absorption of the proximal and distal tubules,
specifically carbonic anhydrase
Decrease of H for exchange for sodium
How does Thiazide lower the Blood preasure
decrease plasma volume and extracellular fluid
How does Thiazide lower cardiac out put
Sterlings law if you decrease the blood returning to the heart aka preload the heart were not work as hard to pump blood back into the systemic system
How does Thiazide lower peripheral resistance
later
What is the most commonly prescribed diaretics
Thiazide
What is a drug we don’t use as a diabetic anymore, its a trap on boards two
Murcurials
Mercurial were known as the
first class diruretics
What is the MOA of Mercurials
block Na reabsorption by releasing Hg to interact with the sulfhydryl group of Na transport receptors in tubules
What is the side effect of mercurials
Decreased Cl transported in asending loop of henle- Risk of Hypochloremic alkalosis
Preparations of Thiazide
Hydrochlorothiazide HCTZ
Chlorothiazide Diuril
HCTZ Hydrochlorothiazide is used for
hypertension
edema of the heart failure and nephrotic syndrome
