test 1 review prep Flashcards
(198 cards)
functions of endocrine system
- Reproduction
- ? and Development
- ? Balance of blood
- ? Balance of blood
- ? balance in blood
- Regulation of cellular ?
- Regulation of cellular ? balance (Cellular Respiration)
- Mobilization of ? system
growth, water, electrolyte, nutrient, metabolism, energy, immune
Endocrine system is ? than Nervous system
slower
endocrine system initiates responses ? and has ? duration responses. it activates via ? at ? locations. the hormones act over ? distances
slower, long, hormones, diffuse, long
water soluble:
- use ? ? systems
- all ? ? based hormones (except TH) are water soluble and cannot diffuse across ? cell membrane
second messenger, amino acid, lipid
fat soluble hormones:
- use ? ? activation
direct gene
- Water soluble hormone, ? messenger, binds to ? on plasma membrane of target cell
- ? receptor sets off a series of reactions (?) that activates Cyclic AMP
- Cyclic AMP activates protein ?
- Water soluble protein hormones cause intracellular ? cascade that has a huge amplification effect
- Number of product molecules ? dramatically so that a single hormone can generate millions of final product molecules
first, receptor, activated, cascade, kinase, enzymatic, increase
- ? Soluble, ? hormones and ? hormones use intracellular receptors to
stimulate Direct Gene Activation. - They diffuse through ? ? into target cells and bind with intracellular receptors forming hormone-receptor complex that diffuses into the nucleus.
- The receptor binds to specific region of DNA and “turns on” a gene that initiates DNA ? and ? to produce a specific protein
lipid, steroid, thyroid, plasma membrane, transcription, translation
? stimuli is the changing blood levels of ions and nutrients directly stimulate secretion of hormones
humoral
? stimuli is when nervous impulse stimulate hormone release
neural
? stimuli occurs when many endocrine glands release their hormones in response to hormones produced by other endocrine glands
hormonal
Most Synthesis and Release of Hormones is Controlled by ? Feedback Systems
negative
Cyclic AMP second-messenger mechanism of water-soluble hormones order:
? binds to receptor
receptor activates ? protein
G protein activates ? cyclase
adenylate cyclase converts ATP to ? (2nd messenger)
cAMP activates protein ?
hormone, G, adenylate, cAMP, kinases
target cells are those cells with ? for the ?.
receptors, hormone
In General, Steroid hormones and thyroid hormone are ? in plasma because they are derived from cholesterol. Steroid hormones circulate in blood bound to plasma proteins and have a ? (longer/shorter) half-life bc all steroid hormones are derived from cholesterol.
insoluble, longer
In General, Protein hormones are ? in plasma. Protein hormones circulate without protein carriers and protein hormones are water soluble and have the ? half-life
soluble, shortest
synergistic (?), antagonistic (? effects), or permissive (one hormone ? the action of another)
together, opposing, amplifies/enabling
Hyposecretion of TH:
Hyposecretion of TH in adults
Can lead to ? also called ? thyroiditis
Symptoms of Myxedema include:
Low ? rate, Low BP, Low ?, Feeling chilled, Constipation, Mental sluggishness
If Hyposecretion of TH due to iodine deficiency in diet is called an ? Goiter
A goiter may develop and Thyroid gland enlarges
Hyposecretion in infants is called ? ? = Cretinism
Mother’s lack of iodine during gestation results in cretinism
myxedema, hashimotos, metabolic, HR, Endemic, Congenital Hyperthyroidism
Hypersecretion of TH:
Most common type of Hypersecretion of TH is ? disease an Autoimmune disease
Body makes abnormal ? that mimic TSH; abnormal antibodies stimulate thyroid gland to release TH at hyper elevated rates
Symptoms of Graves’ disease include
Elevated metabolic rate, Rapid heartbeats, Exophthalmos = eyes protrude
Thyroid Gland secretes Calcitonin in response to high Ca blood levels = Humoral response
Calcitonin stimulates osteoblast and Ca⁺ to move into the bone which ↓ Ca⁺ levels in
blood
? to parathyroid hormone (PTH)
Graves, antibodies, antagonist
functions of blood:
1. ?
2. ?
3. Protection
transportation, regulation
components of blood in a centrifuged blood sample are
55% plasma, 45% blood (erythrocytes), <1% formed elements (buffy coat)
pH of blood is
7.35-7.45
Blood is the Internal ? System
transport
The percentage of total blood volume occupied by erythrocytes is called the
hematocrit
blood is the only ? ? ? in the body
fluid connective tissue