Test 2 stuff (bruzz) Flashcards

(58 cards)

1
Q

What are the cancer stages

A

Stage 1: No metastasis
2: Local invasion
3: Spread to regional structures (lymph nodes)
4: Distant metastasis

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2
Q

Stage 1 cancer is?

A

Cancer confined to the origin

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3
Q

Stage 2 cancer is?

A

Locally invasive

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4
Q

Stage 4 cancer is?

A

Cancer spread to a distant site

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5
Q

Stage 3 cancer is?

A

Cancer that has spread to regional structures like lymph nodes

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6
Q

What are carcinogens?

A

Cancer causing substances

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7
Q

What is pleural effusion?

A

Abnormal collection of fluid in the pleural cavity

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8
Q

What are the types of pleural effusion?

A

Transudative
Exudative
Hemothorax
Empyema
Clothorax

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9
Q

Whats transudative pleural effusion?

A

Caused by cardiovascular disease
High pulmonary capillary pressure
Fluid leaking to pleural space
Fluid leaks due to increase of pressure

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10
Q

What’s exudative pleural effusion?

A

Caused by infection, inflammation, or malignancy of pleura
Leads to fluid, protein, and cells in pleural space

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11
Q

What’s hemothorax (pleural effusion)?

A

Caused by traumatic injury, surgery, or rupture
Blood accumulates in pleural space

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12
Q

What’s empyema? (pleural effusion)

A

Caused by pulmonary infections such as pneumonia
Pus that’s in pleural space

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13
Q

What’s clothorax?

A

Has lymph and fat droplets which can be caused by injury
Chyle accumulates in pleural space

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14
Q

What is pulmonary edema?

A

Excess water in the lungz

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15
Q

What can cause pulmonary edema?

A

Left sided heart failure
Pulmonary Capillary injury
Obstruction of lymphatic system by tumors, lung fibrosis, or surgery

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16
Q

What are some symptoms of pulmonary edema?

A

Dyspnea
Hypoxemia
Increased work of breathing
Inspiratory crackles (rales)
Dullness when percussing
Pink and frothy sputum

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17
Q

What is ashtma and what does it cause?

A

Inflammation of airways
Bronchial hyperresponsiveness
Contrictable airways and reversible airflow obstruction

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18
Q

What are some signs and symptoms of asthma?

A

Expiratory wheezing (breathing out)
Dyspnea
Tachypnea

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19
Q

What are risk factors of Asthma?

A

Allergen Exposure
Urban Residence
Indoor and Outdoor pollution
Tobacco Smoke
Recurrent Respiratory Infections

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20
Q

What is pneumonia?

A

Inflammation of alveoli and bronchioles

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21
Q

What can cause pneumonia?

A

Bacteria and viruses
Gastric secretions aspirated in lungs

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22
Q

What are some symptoms of pneumonia?

A

Coughing
Chest pain
Shortness of breath
Fatigue
Confusion

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23
Q

What are the chromosome aberrations?

A

Polypoid
Aneuploidy
Sex Chromosome Aneuploidy

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24
Q

What is Polypoid Abberation?

A

When the cell has more than the diploid number
AKA more than 2 complete sets of chromosomes
Triploid: Zygote having 3 copies of chromosomes (69 total) usually results in still birth
Tetraploidy: Has 4 copies of chromosomes (92)

25
What is Aneuploidy?
A result of nondisjunction, an error where homologous chromosomes fail to separate normally Trisomy: 3 copies of one chromosome Monosomy: One copy of a given chromosome
26
What is the most common Sex Chromosome Aneuploidy?
Trisomy X (a female who has 3 x chromosomes)
27
What is down syndrome?
Trisomy 21 An extra chromosome (47)
28
What are some down sides to down syndrome?
Intellectual disability Low nasal bridge Low set ears Prone to congenital heart disease Reduced ability to fight infections By 40 they get alzeimers
29
What is tuner syndrome?
Females with only 1 X Underdeveloped ovaries (sterile AHH) Short stature Webbing of the Neck Underdeveloped breasts (aw man) X usually inhereted from mother (gulp)
30
What is Klinefelter syndrome?
Individuals with atleast 2 x and one Y chromosme Male appearance Female like breasts (woah) Small balls (damn) Sparse body hair Long limbs (freaky)
31
What's inbreeding?
Cousin fuckers Increases risk of recessive disorders Also called consanguity
32
What is Duchenne Muscular Dystrophy?
Progressive muscle degeneration X linked disorder (genetic mutation) Males cannot transfer to sons, but can to daughters and they become carriers Son's of female carriers have 50% chance to get it
33
What is Prader Willi Syndrome and Angelman Syndrome?
Deletion of 4 million base pairs of long arm of chromosome 15 Occurs due to a problem with genetic imprinting
34
Which parents gives Prader WIlli Syndrome?
The father
35
What are some signs of Prader Willi Syndrome?
Behavioral Problems Intellectual Disability Short Stature Delayed puberty and constant hunger which leads to obesity
36
Which parent gives off Angelman Syndrome?
The mother
37
What are some signs of Angelman Syndrome?
Frequent laughter and smiling Restlessness (hyperactive) Short attention span Trouble sleeping and need less sleep then other kids Fascination with water
38
What's a pedigree?
A diagram that shows the occurrence of certain traits through different generations of a family
39
What is Cystic Fibrosis?
Autosomal Recessive Disorder involving exocrine glands and cause excessive thick mucus that obstructs lungs and pancreas
40
What are the manifestations of Cystic Fibrosis?
Pancreatic exocrine deficiency Elevation of sodium chloride in sweat Caused by mutations in a single gene on the long arm of chromosome 7
41
What is the treatment for Cystic Fibrosis?
Antibiotics Bronchodilators Anti-Inflammatory Medications Pancreatic Enzyme Replacement Chest Physical Therapy (percussions) Mucolytic Agents Nutrition- More calories
42
What's the normal V/Q ration in lung perfusion?
0.8
43
Is hyoxemia a low or high V/Q?
Low
44
What is shunting?
Inadequate ventilation of well perfused areas of the lung, resulting in wasted perfusion Can occur in atelactasis, ashtma, pulmonary edma and pneumonia NO AIR FLOW
45
What is Alveolar Dead Space?
Poor Perfusion of Well Ventilated portions of the lung which results in wasted ventilation
46
Is Alveolar Dead Space high or low V/Q?
High
47
What's an example of Alveolar Dead Space?
Pulmonary Embolus
48
What is Hypoxia?
Reduced oxygenation of the cells Can be caused by anemia or cardiac disease
49
What is Hypoxemia?
Reduced Oxygenation of Blood Can be caused by shunting Can be caused by Alveolar Dead Space Can be caused by pulmonary edema and lung fibrosis
50
What can a chest tube be used in?
Pneumothorax
51
UV rays can cause what type of cancer?
Melanoma: Cancer in melanocytes (pigment cells) Basal Cell Carcinoma: Lower part of epidermis Squamous Cell Carcinoma: Flat cells that form the surface of the skin
52
Electromagnetic Radiation
Antennas, cell phones May or may not be carcinogenic
53
H. Pylori causes?
75% of stomach cancer
54
Hep B and C can cause?
Liver cancers
55
Epstein Barr Virus can cause?
Nasopharyngeal carcinoma Lymphomas Gastric Adenocarcinoma
56
HPV can cause?
Cervical Penis Vulvar Vaginal Anal
57
What are some cancer treatments?
Chemo Surgery Radiation Therapy Immunotherapy
58
What are the goals of cancer treatment?
Curative Control Palliative