Test 3 Terms & Meds (Cardio/Musculo) Flashcards
(16 cards)
clopidogrel bisulfate (Plavix)
Class? Use?
Class: antiplatelet
Use: prevention of MI, CVA, and vascular death
Class: Antiplatelets
What do they do? (action)
Most frequently used antiplatelet?
This most frequently used antiplatelet is most often used to prevent what?
This class of drugs interfere with platelet membrane function, prevent the release of platelet constituents, and prolong bleeding time, thereby inhibiting platelet aggregation.
Aspirin
Most frequently used to prevent arterial thrombosis.
ASA
acetylsalicylic acid
(Aspirin)
Class? Use?
Class: antiplatelets
Use: reduce risk for MI, TIA, and CVA
dipyridamole
(Persantine)
Class? Use?
Class: antiplatelets
Use: prevention of thromboembolism
Anticoagulants
What do they do? (action)
This class of drugs suppress the production if fibrin, thereby disrupting the coagulation cascade.
Heparin
Class? Use?
Antidote for heparin overdose?
Class: anticoagulants
Use: Prevention an treatment of thrombus or embolism.
Antidote for heparin overdose: protamine sulfate
enoxaparin
(Lovenox)
Class? Use?
Antidote for Lovenox overdose?
Contraindicated for pts w/ allergy/religious objections to what animal?
Class: anticoagulants
Use: Prevention and treatment of thrombus or embolism.
Antidote for Lovenox overdose: protamine sulfate
Pork
warfarin
(Coumadin)
Class? Use?
Antidote for Coumadin overdose?
Class: anticoagulants
Use: Prevention and treatment of thrombus or embolism.
Antidote for Coumadin overdose: Vitamin K
Umbrella Class: Antihypertensives
What do they do? (action)
Because BP depends on cardiac output (CO) and peripheral vascular resistance (PVR), pharmacologic interference of either factor can lead to BP control. Body systems that control CO, PVR, and BP involve the vascular, cardiac, renal, and sympathetic nervous systems. This umbrella class of drugs acts on these body systems to lower BP.
Class: ACE inhibitors
What do they do? (action)
What do the meds all end in?
The class of meds are a classification of antihypertensive medications that interfere with the renin-angiotensin-aldosterone system (RAAS), thereby decreasing BP.
Meds all end with -pril
Class: Beta blockers
What do they do? (action)
What do the meds end in?
What is one big side effect?
This class of meds lower BP by blocking both cardiac and bronchial receptors, eventually causing vasodilation of the arterioles and a reduction of PVR and BP.
Meds end with. -olol
Frequent side effect: bronchoconstriction.
Class: Calcium channel blockers
What do they do? (action)
What do meds end in?
This class of meds inhibit the influx of Ca into muscle cells. Without this influx coronary and peripheral vasoconstriction, myocardial contractility, automaticity, and conduction velocity are depressed in both cardiac and smooth muscle. The result is a relaxation of the smooth muscle of small arteries and a decrease in PVR.
These meds end in -pine
Class: Nitrates
What do they do? (action)
Nitrates affect arteries, veins, and capillaries, but which one primarily?
These are antianginal agents that use direct relaxation on vascular smooth muscles to dilate healthy coronary arteries that atherosclerotic plaque has not encompassed and to improve bld supply to the myocardium, thereby relieving cheat pain.
Acts on arteries, veins, and capillaries, but PRIMARILY on the venous system. Dilates veins so less bld is returned to the heart.
Umbrella Class: Antilipidemics
What do they do? (action)
This class of meds are used to treat hyperlipidemia, which is an increase in lipids in the blood.
Class: HMG-CoA reductase inhibitors (statins)
What do they do? (action)
What do the meds end in?
This class of meds blocks the production of cholesterol, which decreases LDL cholesterol, decreases triglycerides, and INCREASES HDL cholesterol.
These meds end in -statin
Class: Bile acid sequestrant
What do they do? (action)
This class of meds bind bile in the intestine to form an insoluble complex that is excreted in the feces. This causes a partial removal of bile salts, preventing their reabsorption, which leads to a decrease in LDL and serum cholesterol.