Test 4- Blood Flashcards

1
Q

Volume of blood in humans

A

Females: 4-5 L
Males: 5-6 L

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2
Q

What does blood consist of

A

RBC, WBC, Platelets

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3
Q

What does plasma consist of?

A

Water 90%

Proteins 7-9%

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4
Q

dissolves minerals and acts as fluid for transport in blood

A

water

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5
Q

maintains osmotic pressure of blood, lipid transport, immunity, clotting and enzymes

A

proteins

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6
Q

Maintains osmotic pressure of blood

A

albumins

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7
Q

Other solutes found in plasma

A
Food
Metabolic wastes
Respiratory gases
Regulatory substances
Inorganic salts
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8
Q

Formed elements in blood

A

Erythrocytes (RBC)
Leukocytes (WBC)
platelets

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9
Q

Formation of blood cells, which occurs in bone marrow in skull, ribs, vertebrae, and at the ends of long bones

A

Hematopoesis

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10
Q

Biconcave discs with no nucleus (saves space)

A

structure of Erythrocytes/RBC

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11
Q

Life span on 120 days

A

RBC (erythrocytes)

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12
Q

Found only in blood vessels dn sized 7.5 micrometers in diameter

A

Erythrocytes/RBC

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13
Q

Normal number of RBC in blood?

A

Females: 4.2-5.4 million/m3
Male: 4.6-6.2 million/mm3

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14
Q

Oxygen carrying pigment found in blood

A

hemoglobin

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15
Q

Function of RBC

A

to carry oxygen and carbon dioxide

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16
Q

% of RBC in whole blood volume

A

Hematocrit or Packed Cell Volume

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17
Q

What are the layers in a centrifuge of blood?

A

Top- plasma 55% BV

Middle- WBC’s and platelets

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18
Q

Refers to a below normal O2 carrying capacity of the blood

A

Anemia

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19
Q

Causes of anemia

A
dietary deficiencies
pernicious anemia
blood loss
bone marrow failure
hemolytic anemia
20
Q

Body doesn’t make enough blood cells due to lack of B12

A

pernicious anemia

21
Q

RBC’s are destroyed faster than the bone marrow can produce them

A

hemolytic anemia

22
Q

Increased number of RBC’s

A

Polycythemia

23
Q

A hereditary disease which causes abnormally shaped RBC’s which rupture easily

A

Sickle cell disease

24
Q

Larger than RBC’s and have a nucleus

A

Leukocytes (WBCs)

25
Q

Found in blood vessels, lymph and tissue fluid

A

WBC’s

26
Q

5,000-11,000/mm3 of blood

A

WBC’s

27
Q

WBC’s that have granules in the cytoplasm

A

Granulocytes

28
Q

WBC’s that have no granules in cytoplasm

A

Agranulocytes

29
Q

What are the 3 types of granulocytes

A

Neutrophils
Eosinophils
Basophils

30
Q

Granules are small and numerated and give cytoplasm a coarse look

A

Neutrophils

31
Q

First granulocytes to appear at an infection and phagocytize bacteria (65% of WBCs)

A

Neutrophils

32
Q

Protect against infections by parasitic worms and increases in number during allergic reaction (2-5% of WBCs)

A

Eosinophils

33
Q

Granules are large and sparse and release histamines in damaged tissue, causing vascular dilation and smooth muscle contraction in the walls of air passages

A

Basophils (.5-1%)

34
Q

What are the two types of agranulocytes

A

Lymphocytes 25%

Monocytes 3-8%

35
Q

What are 2 types of lymphocytes

A

T lymphocytes

B lymphocytes

36
Q

Directly kill infected cells or cancer cells

A

T lymphocytes

37
Q

Produce antibodies against specific antigens and deactify toxins

A

B lymphocytes

38
Q

Very mobile and very phagocytotic

A

Monocytes

39
Q

Cancers that causes overproduction of abnormal WBC’s

A

leukemia

40
Q

Prevents leukemic cells from moving into the CNS

A

craniospinal irradition

41
Q

Cells involved in clot formation

A

platelets

42
Q

Occurs in individuals that lack clotting ability

A

hemophilia

43
Q

Functions of blood

A
  • maintain homeostasis
  • regulate temp
  • buffers to maintain pH
  • transports
  • Fights infection
44
Q

Prevents blood loss from a broken blood vessel

A

hemostasis

45
Q

What are the 3 major steps in hemostasis

A
  1. Vascular spasm
  2. Formation of platelet plug
  3. Blood coagulation
46
Q

Mother’s immune system may attack infant’s RBC’s (erythroblastosis fetalis)

A

Rh factor

47
Q

What is the treatment for Rh factor?

A

RhoGAM is given to mother to prevent her immune system from producing Rh antibodies