Test 5: The Platelet and Primary Hemostasis

Question 1

Is the process that maintains flowing blood in a fluid state and prevents loss of blood from sites of vascular injury.

Answer 1

Hemostasis

Question 2

Normal hemostasis is dependent upon…

Answer 2

-integrity of vascular wall
- Platelets
-Coagulation system
-fibrinolytic system 

Question 3

What are the stages of hemostasis?

Answer 3

-primary Hemostasis (Formation of platelet plug)
-Secondary hemostasis (Incorporation of fibrin and coagulation factors to form the secondary hemostatic plug (fibrin clot)
-fibrinolysis (Break down and removal of clot formed) 

Question 4

Primary hemostasis consists of what two key parts?

Answer 4

-The vascular system
-Platelets

Question 5

Vascular system consists of three types of blood vessels: 

Answer 5

-arteries and arterioles
-veins and Venules
-capillaries

Question 6

______________ provides a smooth barrier between circulating blood and body tissues

Answer 6

Vascular intima

Question 7

Vascular intima:

The innermost lining is a ___________ of endothelial cells.

Answer 7

Monolayer

Question 8

Capillaries consist of a layer of endothelial cells on a basement membrane and surrounded by __________ -No smooth muscle or fibroblasts 

Answer 8

Pericytes

Question 9

Functions of the endothelial cells are supported by the surrounding __________ and smooth muscles cells.

Answer 9

Fibroblasts

Question 10

 The vascular intima functions to promote….

Answer 10

Coagulation and anticoagulation

-When intact, the endothelial cells produce anticoagulant properties

-When damaged the endothelial cells produce pre-coagulant properties

Question 11

 -The average diameter of platelets in the circulation is _____ Microns


Answer 11

2.5

Question 12

The average number of platelets is…

Answer 12

140,000 to 450,000/ cmm 

Question 13

Play the structure is divided into what three zones?

Answer 13

-peripheral
-Structural/Sol-gel
-Organelle zones