Tetracyclines

Question 1

What are the 3 Tetracycline abx?

Answer 1

doxycycline, minocycline, Tigecycline (DMT)

Question 2

Tetracyclines are ________ spectrum abx.

Answer 2

BROAD (have decent gram + and gram - coverage)
* similar to macrolide coverage

Question 3

Describe tetracycline gram pos coverage?

Answer 3

MSSA- reliable
MRSA - reliable
strep pn - reliable

Question 4

Describe tetracycline gram neg coverage?

H infl?
Mcat?
Enterobacteralrs?

Answer 4

H. infl - reliable
M. cat - reliable
Enterobacterales - unreliable

Question 5

tetracyclien anaerobic coverage?

Answer 5

unreliable

Question 6

Atypical coverage?

Answer 6

EXCELLENT (incl. rickettsiae - aka rocky mt spotted fever)

Question 7

tetracycleins cover what 2 spiral shaped bacteria?

Answer 7

H. pylori and spirochetes (B. burgdoferi, trep. pallidum) - reliable.

Question 8

What are some other UNUSUAL ORGANISMS that tetracyclines reliably cover?

Answer 8

vibrio cholerae, malaria, actinomycetes.

Question 9

Describe TETRACYCLINE main areas of reliable activity?

Answer 9

Reliable:
- G+ : MSSA, MRSA, strep. pneumonia.
- G- : H infl, M.cat
- Atypicals
- spiral bacteria: H pylori and spirochetes (B. burgdoferi, trep. pallidum (syphilis)).
- unusual orgnaisms (cholera, malaria, actinomycetes).

Question 10

what are the 2 groups that tetracycliens have UNRELIABLE coverage against?

Answer 10

Unreliable:
- enterobacteriales and anaerobes