The Cell Cycle Flashcards

1
Q

Why is mitosis important?

A
  • Growth, replacement and repair of tissues in multicellular organisms.
  • Also necessary for asexual reproduction, which is the production of genetically identical offspring from one parent in multicellular organisms.
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2
Q

What is mitosis?

A

The prices of nuclear division by which two genetically identical daughter nuclei are produced and also genetically identical to parent cell.

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3
Q

What happens in prophase in mitosis?

A
  • Chromosomes condense and now visible when stained.
  • The two centrosomes move towards opposite poles.
  • Spindle fibres begin to emerge from the centrosomes.
  • Nuclear envelope breaks down into small vesicles.
  • Nucleolus disappears.
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4
Q

metaphase in mitosis

A
  • each centrosome reaches a pole
  • centrosomes organise spindle fibres -chromosomes line up on equator attached by spindles to centromere
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5
Q

Anaphase in mitosis.

A

-chromosomes split at centromere
- chromatids move to opposite poles centromere first
- chromatids are pulled apart.

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6
Q

Telophase of mitosis.

A
  • nucleolus reforms
  • nuclear envelope reforms
  • spindle breaks down
    -chromatids decondense
  • cytokinesis (division of cytoplasm py constriction)
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7
Q

Prophase 1 in meiosis.

A
  • DNA condenses.
  • nucleolus breaks down
  • nuclear membrane breaks down
  • centrioles move to poles
  • Crossing over may occur at chiasmata, as sister chromatids are close to each other. This causes alleles to swap places, which causes genetic variation.
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8
Q

How are chromosomes arranged in prophase 1 in meiosis and what is this called?

A
  • Chromosomes are arranged side by side in homologous pairs.
  • Pair of homologous chromosomes is called bivalent.
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9
Q

What happens in metaphase 1 in meiosis?

A
  • Bivalents line up along equator of the spindle.
  • Maternal and paternal chromosomes in each pair position themselves independently of the others; this is independent assortment.
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10
Q

What happens in anaphase 1 in meiosis?

A
  • Homologous pairs are separated, spindle fibres contract.
  • Microtubules pull chromosomes to opposite ends.
  • Centromeres do not divide.
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11
Q

Telophase 1 in meiosis.

A
  • Chromosomes arrive at opposite poles.
  • Spindle fibres start to break down.
  • Nuclear envelope forms around two groups of chromosomes and nucleoli reforms.
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12
Q

prophase 2 is meiosis

A
  • Nuclear membrane breaks down.
  • Chromosomes condense.
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13
Q

Metaphase 2 in meiosis.

A
  • Chromosomes line up in a single line along equator of spindle.
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14
Q

Anaphase 2 in meiosis.

A
  • Centromeres divide.
  • Chromatids pulled to opposite poles.
  • 4 groups of chromosomes created that have half n. of chromosomes compared to original parent cell.
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15
Q

What happens after anaphase 2 in meiosis?

A

Cytokinesis creates 4 haploid cells.

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16
Q

What is cytokinesis?

A

Division of cytoplasm.

17
Q

How does cytokinesis occur in animal cells?

A
  • The cell surface membrane pinches inwards creating a cleavage furrow in middle of cell, which contracts, dividing cytoplasm in half.
18
Q

How does cytokinesis occur in plant cells?

A
  • Vesicles from the golgi apparatus gather along equator of spindle.
  • Vesicles merge with each other to make form new cell surface membrane and also secrete layer of calcium pectate which become middle lamella.
  • End product of cytokinesis is meiosis 1 is two haploid cells.
19
Q

What happens in G1 in interphase?

A

-first growth stage
- protein syninesis
- Organene sunresis

20
Q

What does G1 checkpoint check for?

A
  • Cell size
  • Nutrients
  • Growth
  • Damage
21
Q

What happens in G0?

A
  • Resting
  • If cell hasn’t reached G1 criteria.
  • Due to damage/ limits.
22
Q

synthesis in interphase.

A
  • DNA synthesis.
  • Chromosomes are checked to ensure they have been replicated.
  • If replication not successful, cycle stops.
23
Q

What happens in G2 in interphase?

A
  • Rapid cell growth.
  • Molecules for cell division synthesised.
  • Cycle delayed for any repair.
24
Q

What does G2 checkpoint check for?

A
  • Cell size.
  • Replication.
  • Damage.
  • Chromosome attachment.
25
Q

What happens if DNA damage is discovered at the G2 checkpoint?

A

The cell cycle is halted and the cell tries to repair the DNA.