the integumentary system 1 Flashcards

1
Q

what does the integumentary system include

A

the body covering including the skin, nails and hair

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2
Q

what are the 2 main parts of the integumentary system

A

epidermis and dermis

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3
Q

what is the epidermis

A

surface epithelial layer of the skin

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4
Q

what is the dermis

A

the deeper connective tissue layer of the skin

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5
Q

what is not part of the skin

A

deep dermis

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6
Q

what 2 basic tissues does the skin consist of

A

epithelial and connective

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7
Q

what are the 2 fundamental layers of skin

A

outer epidermis and inner dermis

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8
Q

what is the epidermis made of

A

keratinized stratified squamous epithelial

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9
Q

what 4 cell types is the epidermis made of

A

keratinocytes
melanocytes
Langerhans cells
merkel cells

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10
Q

how much of the epidermis is keratinocytes

A

90%

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11
Q

how many layers are made up by keratinocytes

A

4-5

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12
Q

what do keratinocytes do

A

produce keratin
protect skin
waterproof

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13
Q

name the sublayers of the epidermis

A

stratum basale
stratum spinosum
stratum granulosum
stratum lucidum
stratum corneum

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14
Q

how long does the renewal of the epidermis take

A

3-4 weeks

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15
Q

what is the role of the stratum basale

A

stem cells of the epidermis

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16
Q

describe the structure of the stratum basale

A

single layer of low columnar or cuboidal cells at the base of the epidermis

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17
Q

describe the structure of the stratum spinosum

A

several layers of polyhedral cells joined by many desmosomes

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18
Q

describe the structure of stratum granulosum

A

few layers of flattened cells with cytoplasmic granules
nuclei begins to degenerate

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19
Q

describe structure of stratum lucidum

A

several layers of flattened skin
nuclei hardly visable

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20
Q

when can the stratum lucidum not be identified

A

in thin skin

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21
Q

describe the structure of stratum corneum

A

several layers of flattened keratinised (dead) cells, embedded in a dense matrix of proteins.

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22
Q

what parts of the body contain thick skin

A

palms of hands and soles of feet

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23
Q

what do melanocytes do

A

produce melanin
transfer pigment to keratinocytes

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24
Q

what amount of the epithelial cells are melanocytes

A

8%

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25
what do Langerhans cells do
immune response
26
where are langerhans cells found
stratus spinosum
27
describe how langerhans cells preform their function
cells that engulf foreign materials that invade the epidermis
28
where are merkel cell complexes found
stratum basale
29
how many factors contribute to skin color
3
30
how many factors contribute to skin color
3
31
what factors contribute to skin color
amount of melanin in the epidermis amount of carotene amount of oxygen bound to haemoglobin
32
what is albinism
an inherited recessive disorder little or no melanin
33
what is melasma
dark brown symmetric areas on the face and neck
34
what is vitiligo
smooth white patches in skin due to loss of melanocytes
35
what are birthmarks
abnormal blood vessels or malformed pigment cells
36
how % of skin cancer is basal cell carcinoma
around 75%
37
describe features of basal cell carcinoma
grows very slowly, highly treatable and starts in the basal cell layer of the epidermis
38
what % of skin cancer is squamous cell carcinoma
around 20%
39
describe features of squamous cell carcinoma
middle aggression, but can be treated
40
what % of skin cancer is melanoma
roughly 5%
41
what % of skin cancer deaths are due to melanoma
73%
42
describe features of melanoma
usually in a mole and spreads quickly
43
what is jaundice
an abnormal yellow skin tone that usually signifies a liver disorder
44
what are the accessory structures
hair skin glands nails
45
what is hair made of
fused keratinized cells
46
what items make up hair
shaft and root
47
name the epidermal glands
sebaceous glands sudoriferous/ sweat gland ceruminous glands
48
what do sebaceous glands do
secrete oily sebum
49
what do ceruminous glands do
produce earwax
50
what are nails made of
packed hard dead keratinized cells
51
what are the functions of the integumentary system
temperature regulation protection sensory reception excretion and absorption vit D synthesis
52
where is aging of the integumentary
mainly dermis
53
what contributes to the aging of the integumentary
loss of collagen fibres, loss of electacity, loss of immune responses, thinning of skin
54
what is acne stimulated by
androgens
55
what induces skin cancer
ultraviolet rays of the sun
56
where is skin cancer most commom
fair skinned and the elderly
57
describe most skin tumours
benign and do not metastasize (spread to other sites)
58
what 2 key factors can contribute to skin cancer
environment and genes
59
name the 3 types of the skin cancer
basal cell carcinoma squamous cell carcinoma malignant melanoma
60
describe basal cell carcinoma
most commom least dangerous arrises from the cells of the stratum basale and eventually invades the dermis
61
how does basal cell carcinoma appear
a small shiny bump that develops a central depression and a beaded pearly edge
62
where does basal cell carcinoma normally occur
on the face
63
how is basal cell carcinoma treated
surgically removed and radiation therapy
64
where does squamous cell carcioma arise from
keratinocytes of the stratus spinosum
65
where does squamous cell carcioma normally appear
scalp, ears, lower lip or back of hand
66
what does squamous cell carcinoma look like
raised reddened scaly appearance
67
how many cancer cases are malignant melanoma
5%
68
where does malignant melanoma arise from
melanocytes of a preexisting mole
69
what is a first degree burn
involves only the epidermis
70
what is a second degree burn
involves the epidermis and part of the dermis but leaves some of the dermis intact
71
what is a third degree burn
the epidermis, dermis and often some deeper tissues are completely destroyed