The Physical Basis Of Heredity Flashcards

(67 cards)

1
Q

Where is the “heredity” factor?

A

In the nucleus

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2
Q

Do chromosomes occur in pairs?

A

Yes

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3
Q

When do chromosomes separate?

A

At meiosis

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4
Q

How do members of chromosome pair appear to segregate?

A

Independently

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5
Q

Most animals have what kind of cells?

A

Diploid

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6
Q

Diploid

A

2n or two sets (one pair) of chromosomes

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7
Q

Autosome

A

Pairs 1-22 the “not sex chromosomes”

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8
Q

What is the last pair of chromosomes?

A

Sex chromosomes

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9
Q

XX

A

Female

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10
Q

XY

A

Males

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11
Q

Homologous chromosomes

A

Paired corresponding chromosomes

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12
Q

What are homologous chromosomes similar in?

A

In morphology, centromere position, and the genes that each carry

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13
Q

Centromere

A

The largest constriction site on the chromosome

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14
Q

What is the site of spindle fiber attachment during mitosis?

A

The centromere

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15
Q

How many chromatids per centromere?

A

2

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16
Q

Sister chromatids

A

The two chromatids that make up one chromosomes

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17
Q

Telomere

A

Tips of the chromosome

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18
Q

How do you describe chromosomes?

A

By centromere position

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19
Q

Telocentric

A

Centromere at tip

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20
Q

Acrocentric

A

Centromere close to tip

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21
Q

Submetacentric

A

Centromere off center

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22
Q

Metacentric

A

Centromere at middle

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23
Q

Karyotype

A

A chart arranging chromosome pictures according to their size, grouped by pairs of homologs

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24
Q

How are chromosomes numbered in Karyotypes?

A

In order of size and centromere position

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25
Ideogram
A schematic representation of a chromosome
26
Shorter arm in ideogram
P arm
27
Longer arm in ideogram
Q arm
28
How are major banding regions in ideograms indicated?
With numbers
29
Microsomes
artificial structures derived from pieces of endoplasmic reticulum (ER) formed during tissue homogenization
30
Cytogenetic
Genetic sub discipline that focuses on chromosome variations
31
What can abnormal gene or chromosome copy numbers lead to?
Genetic abnormalities
32
When are chromosomes visible (this is the time we Karyotype)?
During metaphase when the chromatids are lined up
33
What is chromatin made of?
DNA and protein
34
Chromatin
the material of which the chromosomes of organisms other than bacteria (i.e., eukaryotes) are composed. It consists of protein, RNA, and DNA.
35
Where is chromatin located?
Outside of of nucleolus
36
Cell Cycle
G1 —> S —> G2 —> Mitosis
37
What two steps make up interphase?
G1 and S
38
G1 Phase
Time cell growth before DNA is copied (chromosomes unduplicated)
39
S Phase
Time of cell growth when the DNA is copied (all chromosomes duplicated)
40
G2 Phase
Time after DNA replication the cell prepares to divide
41
What are the four phases of mitosis?
1. Prophase 2. Metaphase 3. Anaphase 4. Telophase
42
Prophase
When microtubules attach to the centromeres of the sister chromatids
43
Metaphase
Spindle fibers line up chromosomes in the middle
44
Aster
Where spindle fibers come out from
45
Anaphase
Spindle fibers begin pulling sister chromatids apart
46
Telophase and cytokinesis
Sister chromatids are separated and cleavage furrow and nucleus/nuclear envelope begin to form
47
When does cytokinesis begin?
Towards the end of anaphase
48
When does cytokinesis end?
Finishes after telophase
49
What happens during cytokinesis?
-Cleavage furrow forms -microfilaments pull plasma membrane inward around the cell -pinches the cell in two
50
Daughter cells are _____.
2n
51
What is the function of mitosis?
Growth, including repair and maintenance
52
Where does mitosis occur in?
Somatic/body cells
53
What is the mechanism of mitosis?
Chromosomes are duplicated once then cytoplasm is divided
54
What is the outcome of mitosis?
Maintains the diploid chromosomes number 2n —> 2n
55
Effect of mitosis
Two diploid daughter cells
56
Function of meiosis
Gamete production (sperm/eggs)
57
Where does meiosis occur at?
Germ cells in gonads (testes/ovaries)
58
Mechanism of meiosis
Chromosomes are duplicated twice then the cytoplasm is divided
59
Outcome of meiosis
Halves the diploid chromosome number 2n—>n
60
Effect of meiosis
Four haploid daughter cells
61
What is meiosis?
Single DNA replication two division of the cytoplasm
62
What happens during meiosis I?
- separation of homologs -reduces chromosomes to haploid
63
What happens during meiosis II?
Equational division; sister chromatids of haploid cells are separated
64
Genetic recombination
As chromosomes move closer together synapsis occurs and chromatids break and exchange genetic information
65
What species can you cross?
Species with the similar chromosome numbers
66
Why are mules infertile?
Because a horse has 64 chromosomes and a donkey has 62 so when a mule is born it has 63.5 and cannot reproduce with other mules
67
Why can ligers or tigons reproduce but not mules?
Because most cats have the same chromosome number so hybrids will have the same as well and can reproduce