Three Flashcards

(36 cards)

1
Q

What are 5 questions that should be asked as part of the clinical method of neurology?

A
  1. In every patient there is the inherent question, is the nervous system functioning normally or is it sick?
  2. If the nervous system is impaired, in what portion (or portions) is the pathology localized?
  3. Wherever the pathology is located, what is the tempo of the underlying pathophysiologic process?
  4. What diagnostic studies verify the clinical formulation?
  5. What treatment is appropriate?
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2
Q

What are cardinal manifestations of neurological disorders?

A
  1. Alterations in Consciousness
  2. Abnormalities of Intellect and Behavior
  3. Impaired Motility
  4. Disorders of Stance and Gait
  5. Pain
  6. Disorders of Special Senses
  7. Abnormal Eye Movements and Pupillary Reactions
  8. Changes in Sleep
  9. Autonomic Disorders
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3
Q

What are two ways that alterations in consciousness can occur? What are some possible results?

A
  1. Alterations in Consciousness

Temporary changes in consciousness occur with reduction in blood flow, producing syncope, or a neuronal discharge, commonly manifested by a focal or generalized seizure. A protracted alteration in the metabolic function of the reticular activating system and/or its cerebral connections results in altered consciousness that ranges from lethargy to stupor to coma.

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4
Q

What are some examples of abnormalities of intellect and behavior?

A

Disturbed thinking (e.g., poor logic, confusion), altered affect and loss of higher cortical functions (e.g., memory, language, calculations, judgment, abstract thinking, etc.) reflect both diffuse and focal disease in the cerebral cortex.

Examples of altered behavior include the irritability of hypoxia, the apathy of dementia or sudden alteration in ordinary activity, as occurs with an absence or partial complex seizure.

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5
Q

What are some examples of impaired motility?

A

Disturbances in motility are manifest by weakness, altered tone, changes in muscle bulk or disorders in movement. The distribution of the weakness (e.g.,
paraparesis versus hemiparesis), the type of altered tone, the size of the muscle and the form of abnormal movements (e.g., myoclonic jerks, chorea, hemiballismus, tremor) are helpful in localizing the pathologic disturbance.

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6
Q

What are some examples of disorders of stance and gait?

A

Alterations in the posture of the upright stance are evident in a tilt, stoop or widened base and may characterize a neurologic disturbance. Similarly, careful observation of an altered gait may show instability, festination, altered tone in one leg, high steppage, waddling or tottering and give clues to the underlying neurologic diagnosis.

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7
Q

What are 6 important aspects of pain that characterize its pathogenesis? What are 3 examples of altered sensation and what do they usually signal?

A

Pain is a fundamental product of altered sensation due to functional or structural disturbances. Its mode of onset, location, duration, severity, character and frequency characterize its pathogenesis. Headache, nerve root pain and
paravertebral pain have important implications to neurologic disease. Altered sensation such as paresthesias (tingling), hyperpathia (excessive sensitivity) and causalgia (burning) signal a neurologic, often peripheral, disturbance.

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8
Q

What are some examples of disorders of special sense?

A

Loss of a special sense or alteration of that sense, e.g., the foul smell of olfactory hallucinations, bright flashes (photopsias), ringing (tinnitus) and spinning
sensation (vertigo) implicate a disturbance along the anatomic pathway for that special sense.

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9
Q

What are some examples of abnormal eye movement and pupillary responses?

A

Paralysis of eye movements includes disturbance in horizontal or vertical conjugate gaze. Ocular nerve palsies produce disparate eye movements. The
resulting misalignment of the ocular globes causes the patient to see double images (diplopia). Disrupted parasympathetic innervation to the sphincter pupillae muscle or sympathetic supply to the dilator pupillae muscle produces changes in the pupil’s size and in the reaction to light and near fixation with respect to the parasympathetic pathway.

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10
Q

What are 3 specific examples of abnormal eye movement and pupillary response disorders? What are their symptoms?

A

Oculomotor nerve palsy: mydriasis, ptosis, down and out position

Abducens nerve palsy: eye will not look outwards (right eye won’t look right)

Horners syndrome: Pupil doesn’t dilate in low light.

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11
Q

What are some examples of changes in sleep?

A

Lack of sleep, excessive sleep and altered sleep (e.g., sleep paralysis, somnambulism, sleep apnea, enuresis) all result from dysfunction mediated within
the central nervous system.

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12
Q

What are some examples of autonomic disorders?

A

Common disorders of the autonomic nervous system are expressed in the inability to regulate blood pressure during orthostasis, maintain control of the bladder, attain or sustain sexual intercourse due to failure in penile erection, or regulate water metabolism or the appetite.

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13
Q

What are the nine steps of a neurological examination?

A
A. Mental Status and Higher Cerebral Function 
B. Cranial Nerves 
C. Motor 
D. Sensation 
E. Coordination: 
F. Reflexes 
G. Autonomic Function 
H. Head, Neck and Spine 
I. Palpable or Tender Peripheral Nerves
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14
Q

What are 12 steps for testing mental status and higher cerebral function?

A
  1. Appearance and behavior
  2. Level of consciousness
  3. Orientation - time, place, person
  4. Memory
    - immediate: retention of sequential digits forward or backward
    - recent: recall of known items or events
    - past: recollection of events in childhood, school, marriage, work
  5. General information (local and world events)
  6. Calculations (double digit addition and subtraction; making change
  7. Ability to abstract: interpretation of proverbs; similarities
  8. Judgment and insight
  9. Mood
  10. Hallucinations and delusions
  11. Speech
    a. Articulation, phonation, volume; Dysarthric features: slurring, disorders of pitch and tonal inflection
    b. Fluency (rate of speech) and correctness of spontaneous speech
    c. Repetition: syllables, words, phrases
    d. Comprehension of spoken language (one, two or three stage motor commands)
    e. Naming of objects and their parts
    f. Reading
    g. Writing
  12. Special tests for apraxias and agnosias
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15
Q

How are the 12 cranial nerves examined for function?

A

I. Smell (tobacco, cloves, etc.)
II. Visual acuity and visual fields (including double simultaneous stimulation)
III. Pupil size and reaction to light and accommodation
III, IV, VI. Eye movements: cardinal directions of gaze; convergence
V. Strength and bulk of masseter, temporalis, pterygoid muscles; Sensation over three divisions (trigeminal) of the face; Corneal reflex; Jaw jerk
VII. Facial movements: eye closing, grimace, smile
VIII. Examination of hearing:
Otoscopic examination
Recognition of whispered words or quiet sounds
Weber and Rinne tests with 512 Hz tuning fork
Examination of the vestibular system
Caloric testing.
Positional changes (inversion) of the head to induce nystagmus and vertigo
IX,X. Palatal movement, Swallowing, Phonation, Gag reflex, Laryngoscopic examination - indirect for cord movement
XI. Strength and bulk of sternomastoid and trapezius muscles
XII. Inspection of tongue for atrophy, fasciculations
Protrusion of tongue in midline and laterally

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16
Q

What are 5 ways to test motor ability in a neuro exam?

A
  1. Bulk: Note wasting or hypertrophy
  2. Tone - by passive movement of the limb and review of posture
  3. Power: Major functional groups about each joint, skilled movements, including fine motor movements
  4. Involuntary movements: tremor, myoclonus, chorea, dystonia,
  5. Posture
17
Q

What are 10 ways to test sensation in a neuro exam?

A
  1. Pinprick
  2. Temperature
  3. Touch
  4. Vibration
  5. Joint position
  6. Two-point discrimination
  7. Localization of touch
  8. Number writing on palm or digit
  9. Appreciation of texture, size, shape (for astereognosis)
  10. Double simultaneous stimuli (for extinction)
    Rapid movements: side-to-side. Lingual sounds (“la, la, la”)
18
Q

How do you test coordination in a neuro exam?

A

finger-to-nose, heel-to-shin and knee, rapid alternating movements
Station: Normal stance and Romberg
Gait: Normal walk and tandem

19
Q

How do you check reflexes in a neuro exam?

A
  1. Tendon jerks: jaw, biceps, triceps, brachioradialis, finger flexors, knee, ankle, biceps femoris, semimembranosus
  2. Superficial: abdominal, cremasteric, anal, bulbocavernosus
  3. Pathologic: suck, grasp, avoiding, plantar (Babinski) response
20
Q

What are 5 ways to check autonomic function in a neuro exam?

A
  1. Sweating, piloerection
  2. Skin temperature
  3. Bowel, bladder and sexual function
  4. Vasopressor and cardioacceleratory responses
  5. Blood pressure and pulse (supine, sitting, standing)
21
Q

What are 4 things that should be check in the head, neck,, and spine in a neuro exam?

A
  1. Signs of meningeal irritation
    Nuchal rigidity, Kernig’s sign, Brudzinski’s sign
  2. Cranium
    Size and shape
    Signs of trauma, e.g., ecchymosis about orbit or over mastoid eminence (Battle’s sign)
    Tenderness
  3. Spine: configuration; tenderness
  4. Cerebral blood vessels
    Pulsation: carotid, temporal, subclavian, angular arteries
    Blood pressure in each arm
    Bruits - carotid, subclavian, suboccipital, temporal
22
Q

What are 3 nerves that should be checked for palpability or tenderness in a neuro exam?

A

ulnar, peroneal, mental

23
Q

What are the symptoms of primary muscle disorder?

A

The symptoms are usually bilateral, symmetrical and proximal, being distributed in limb-girdle muscles of the shoulders and hips. In many forms of muscle disease the sternocleidomastoids are weak. Muscles may be thin and hypotonic.
Reflexes are usually normal except when muscles are severely wasted.

24
Q

What are the symptoms of a peripheral nerve disorder?

A

The signs of weakness and sensory loss are limited to the territory of the affected nerve whose trunk may be tender or thickened. Loss of the tendon reflex and of muscle mass (wasting) may be present, too. Multiple peripheral nerves are involved simultaneously or in sequence.

25
What are the symptoms of symmetrical polyneuropathy?
This condition usually begins in the distal lower limbs owing to affectation of the longest members of a class of fiber. Depending on the pathologic cause, sensory or motor fibers or both are involved.
26
What are the symptoms of nerve root disorders?
All motor and sensory symptoms and signs are confined to the territory of the affected root (or roots). Compression or movement of the spine or the rise induced in intraspinal pressure by coughing or straining may result in paroxysms of pain that "shoot" or radiate into the territory of the affected root. Spinal pain, muscle wasting, diminished tendon reflexes and reduced sensation belonging to a single spinal root characterize the clinical picture.
27
What is the clinical picture of a spinal cord disorder?
Sensory and motor impairment need not be symmetrical but sparing of segments above a certain level and involvement below a certain level on the body are distinctly evident. Several different types of spinal syndromes occur, e.g. hemisection (Brown Sequard syndrome or transection).
28
What is the clinical picture of a brainstem disorder?
Brainstem disorders are suggested by a combination of deficits in cranial nerves II to XII that are associated with cerebellar disturbances (ataxia of limb or gait) or long tract abnormalities (spastic weakness or loss of sensation). Owing to the anatomy of the brainstem, the cranial nerve deficits are ipsilateral and the long tract motor and sensory signs are contralateral (“crossed”).
29
What is the clinical picture of a cerebellum disorder?
Incoordination involves the limbs ipsilateral to a lateralized lesion. Bilateral signs indicate diffuse disease. Altered speech, impaired truncal balance, wide-based stance, and staggering gait characterize midline disease.
30
What is the clinical picture of diencephalon and cerebral hemispheres disorders?
With single lesions, the signs and symptoms are limited to the opposite side of the body. Select features of cerebral disease include reduced intellect, loss of memory, language dysfunction, focal convulsions, disorders of recognition (agnosia) and impaired use of normally limbs for purposeful acts (apraxia).
31
What are some examples of apoplectiform illness? What is the clinical picture?
1. Apoplectiform Illness (Stroke; Hemorrhage; Head Injury) The onset is abrupt and the maximal effect present at the beginning. Gradual improvement may follow. The course of recovery is variable. The time span of the whole event may vary from minutes or hours to days or weeks.
32
What is an example of Stepwise Progressive Disease? What is the clinical picture?
2. Stepwise Progressive Disease (Multiple Small Vessel Infarction) The illness proceeds with abrupt, but mild, loss in function, but each decline is followed by a period of relative stability.
33
What are examples of causes of Steadily Progressive Disorders? What is the clinical picture?
3. Steadily Progressive Diseases (Tumors and Degenerative Disorders) Early on the progression is insidious, often relatively asymptomatic, but the course of the illness advances steadily and is inexorably progressive.
34
What is an example of Relapsing Remitting Disease with Secondary Progression? What is the clinical picture?
4. Relapsing Remitting Disease with Secondary Progression (Multiple Sclerosis) This course is characterized by the subacute development of symptoms followed by slow and incomplete improvement maintained for variable periods. Relapses may follow rapidly upon one another or be separated by long intervals. The illness may seem progressive when relapses occur in close succession. Over time, disability develops and increases with each relapse.
35
What is an example of Acute/Subacute Illness? What is the clinical picture?
5. Acute/Subacute Illness (Infectious Disease) An acutely or subacutely evolving illness which reaches its peak and usually fully recovers after a stable period. In some instances a late second phase may occur.
36
What are two examples of Episodic illness? What is the clinical picture?
6. Episodic Illness (Epilepsy; Migraine Headaches) The course is marked by clusters of attacks. The interval often is punctuated by an isolated attack. The time basis varies from patient to patient yet remains fairly constant for the individual.