Thyroid Gland Flashcards

1
Q

Thyroid gland is where and what

A

Largest pure endocrine gland, located in front of the neck

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2
Q

What is the thyroid gland composed of

A

Follicles

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3
Q

What are the follicles lined by

A

single layer of epithelial cube shaped cells

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4
Q

What is between the follicles

A

Connective tissue that contains parafollicular cells

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5
Q

What two hormones are produced by TG

A

Thyroid Hormone and Calcitonin

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6
Q

Thyroid Hormone

1) What is it produced and stored by
2) Effects mainly what
3) Promotes what
4) What two sub hormones is it composed of
5) What is the major sub hormone
6) Where is the minor sub hormone produced
7) What is the main difference between the 2 sub hormones

A

1) Thyroid follicles
2) Metabolism
3) Growth
4) thyroxine (T4) and triiodothyronine (T3)
5) T4
6) Target tissues by conversion of T4 to T3
7) T4 has 4 iodine while T3 has 3

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7
Q

Calcitonin

1) Produced by
2) What does it lower
3) What does it promote
4) What is its release controlled by

A

1) Parafollicular cells
2) Calcium ion level in blood
3) Bone formation by stimulating osteoblasts
4) Level of calcium ions in blood

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8
Q

What is hyperthyroidism

A

Increased levels of thyroid hormone

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9
Q

Hyperthyroidism causes what

A

Graves Disease/Thyrotoxicosis

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10
Q

Manifestations of Graves disease

A

increased metabolic rate, profuse sweating, increased heart rate, nervous agitation, exophthalmos (bulging eyes)

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11
Q

Hypothyroidism causes what

A

Cretinism in children or myxoedema in adults

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12
Q

Manifestations of Hypo

A

Low metabolic rate, lethargy, mental sluggishness and poor concentration, puffy skin around eyes and swollen limbs due to fluid accumulation and dry thick skin

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