TMN1 and 2

Question 1

NK is part of ….immunity

Answer 1

INNATE

Question 2

Digestive enzyme in mouth is ….. barrier

Answer 2

PHYSICAL BARRIER

Question 3

Stomach acid is a …..

Answer 3

PHYSICAL BARRIER

Question 4

MUCOUS and CHEMICAL secretions are …. barrier

Answer 4

PHYSICAL BARRIER

Question 5

Defensin are….

Answer 5

antimicrobial peptides

Question 6

Without …. infections would go unchecked and wounds would NOT heal

Answer 6

INFLAMMATION

Question 7

Is this sequence correct: Edema, PMN, Monocyte/Macrophage, Tissue repair and regeneration (FROM INITIATION to RESOLUTION) steps of INFLAMMATION

Answer 7

Correct

Question 8

For acute inflmmation, what happen prior to arrival of PMN

Answer 8

Edema

Question 9

Monocyte/Macrophage arrive ….. PMN

Answer 9

AFTER

Question 10

Parasite’s …. is recognized by immune system

Answer 10

GPI anchor

Question 11

Innate is triggered by

Answer 11

PAMPs and DAMPs

Question 12

peptidoglycan is a ….

Answer 12

PAMPs

Question 13

CpG DNA is a…

Answer 13

PAMPs and DAMPs!

Question 14

Flagellin is a….

Answer 14

PAMPs

Question 15

Lipteichoic Acid is found in ….bacteria and is a ….

Answer 15

GRAM POSITIVE, PAMP

Question 16

Viral sRNA is ….

Answer 16

PAMPs

Question 17

LPs is a….

Answer 17

PAMPs

Question 18

Viral dsDNA is a….

Answer 18

PAMPs

Question 19

TLRs are w/in …. and can also be …..

Answer 19

Vesicles or Membrane Bound

Question 20

…. are cytoplasmic Pattern Recognition Receptors

Answer 20

NOD like Receptor

Question 21

….use MyD88 or TRIF for signal transduction

Answer 21

Toll-like Receptor Family

Question 22

….discovered in drosphilia

Answer 22

TLR

Question 23

….located in endosome

Answer 23

TLR3, TLR7, TLR9, TLR8

Question 24

….use NF-kB

Answer 24

TLR

Question 25

....critical linke b/w innate and adaptive

Answer 25

TLR

Question 26

NLR's names are based on....

Answer 26

their N-Terminal effector domains

Question 27

......common to all NLR

Answer 27

Nucleotide-binding domain (NOD)

Question 28

......c-terminal leucin Rich Repeat

Answer 28

NLR

Question 29

......variable N-terminal interaction Domain

Answer 29

NLR

Question 30

NOD1 and 2 act as ....sensors of ......

Answer 30

NOD1 and NOD2 act as INTRACELLULAR sensors of BACTERIAL INFECTION recognize bact cell wall frag proteoglycans viral RNA

Question 31

.....involved in inflammasome formation and activated by PAMPs and DAMPs

Answer 31

NLRPs

Question 32

inflammasome activates.... which activates.... and .......

Answer 32

inflammasome of NLRPs activate CASPASE-1 which activates IL-1beta (from Pro-IL-1Beta) and IL-18 (from pro-IL-18)

Question 33

NFkB drives ...... and ..... gene transcription

Answer 33

prol-IL-1beta and pro-IL-18 and infalmmasome component NLRP3 example gene transcription