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FINALS PHARMA > TOPIC 11 > Flashcards

TOPIC 11 Flashcards

(42 cards)

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1
Q

Growth hormone
Thyroid stimulating hormone
Adrenocorticotropic hormone
Gonadotropin follicle stimulating Hormone
Luteinizing hormone
Prolactin

A

Anterior Pituitary gland

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2
Q

Antidiuretic hormone
Oxytocin

A

Posterior pituitary gland

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3
Q

Thyroid releasing hormone (TRH)
Corticotropin releasing hormone (CRH)
Growth hormone-releasing hormone (GH_RH)
Growth hormone -inhibiting hormone (GH-IH)

A

Hypothalamus

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4
Q

Thyroxine (T4)
Triiodothyronine ( T3)

A

THYROID GLAND HORMONES

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5
Q

Controls metabolic rate and activity of nearly every tissue and organ
Increase CO
Increase 02 consumption
Carbohydrate use , proteins and fats
Affect heat regulation and menstrual cycle

A

Thyroid hormone

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6
Q

HYPOTHYROIDISM cause in adult_______children_______

A

Myxedema ( adult)
Cretinism ( children)

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7
Q

Lethargy
Puffy eyelids and face
Thick tongue
Slow speech with hoarseness
Lack of perspiration
Slow pulse
Cold intolerance
Abnormal menses

A

HYPOTHYROIDISM SX

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8
Q

Drug of choice for replacement therapy
Increases T3 and T4
Given per orem

A

Levothyroxine sodium (Levothyroid, Synthroid)

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9
Q

Tachycardia
Chest pain
Palpitations
Excess sweating

A

HYPERTHYROIDISM SX

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10
Q

Reduce excess T3 and T4
Thiourea derivatives
1. Propylthiouracil (PTU)
2. Methimazole(Tapazole)

A

HYPERTHYROIDISM DRUG THERAPY

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11
Q

Inhibits thyroid hormone synthesis
PO

A

METHIMAZOLE (TAPAZOLE)

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12
Q

Inhibits conversion of T4 and T3
Maybe used before surgery or radioactive iodine tx palliative control
Toxic goiter
PO

A

PROPYLTHIOURACIL (PTU)

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13
Q

Reduce size and vascularity of thyroid gland

A

STRONG IODINE SOLUTION (LUGOL’S SOLUTION)

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14
Q

Regulates calcium in the blood

A

Parathyroid hormone

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15
Q

Mobilizing calcium from bones
Promotes Ca absorption from the intestine
Promotes Ca reabsorption from the renal tubule

A

Parathyroid hormone

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16
Q

PTH deficiency
Vitamin D deficiency
Renal impairment
Diuretic therapy

A

Hypocalcemia

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17
Q

Promote calcium replacement in the Gl tract
Promote reabsorption of calcium from the renal tubules
Activates Vitamin D

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A

PTH replacement

18
Q

Vitamin D analogue that promotes calcium absorption from the Gl tract and secretion of Calcium from bones to the bloodstream

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A

Calcitriol-PO

19
Q

Treatment of Paget disease
HyperPARAthyroidism
Hypercalcemia Subcutaneous

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A

CALCITONIN - human (CIBACALCIN)
CALCITONIN - salmon (MIACALCIN)

20
Q

Treatment of Paget disease
HyperPARAthyroidism
Hypercalcemia
PO

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A

CINACALCET ( SENSIPAR)

21
Q
  1. LISPRO (Humalog)
  2. ASPART (Novolog)
  3. GLULISINE (Apidra)
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A

RAPID ACTING INSULIN

22
Q
  1. INSULIN REGULAR (Humulin R)
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A

SHORT ACTING INSULIN

23
Q
  1. ISOPHANE, NPH (Humulin N, Novolin N)
  2. SUSP LENTE (Humulin L, Novolin L)
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A

INTERMEDIATE ACTING INSULIN

24
Q
  1. ULTRALENTE INSULIN
  2. INSULINE GLARGINE (Lantus
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A

LONG ACTING INSULIN

25
1. HUMULIN 70/30 2. INSULIN ISOPHANE NPH 50/50 3. HUMALOG 75/25
INSULIN COMBINATIONS
26
- Decrease hepatic production of glucose from stored glycogen - Increases insulin receptor sensitivity - Decrease absorption of glucose in the small intestine
METFORMIN (Glucophage)
27
Improves glucose control and decrease insulin resistance
ALPHA GLUCOSIDASE INHIBITOR
28
Insulin enhancing agents Improves blood glucose control and increase insulin sensitivity
THIAZOLIDINEDIONES
29
Produced corticosteroids: Glucocorticoids ( Cortisol) Mineralocorticoids (Aldosterone)
Adrenal cortex
30
Promote sodium retention and potassium excretion
Corticosteroids
31
Results from adrenal insufficiency
Addison's disease
32
Results from hypersecretion of the adrenal glands
Cushing's syndrome
33
Cause sodium retention Water retention Potassium loss Increase blood pressure
Glucocorticoids
34
Has antiinflammatory, anti-allergy, antistress effect
Cortisol /Cortisone drugs
35
Multiple sclerosis Rheumatoid arthritis Myasthenia gravis
Indications for Glucocorticoid therapy
36
Adrenal insufficiency PO
CORTISONE
37
Adrenal insufficiency Inflammation PO, IV, Rectal
HYDROCORTISONE
38
Anti-inflammatory Immunosuppressive effect PO, IM, IV
PREDNISOLONE
39
Anti-inflammatory Anti-asthma PO, IM, IV
BETAMETHASONE
40
Controlled by renin-angiotensin system Promotes fluid balance by promoting renal reabsorption of sodium from renal tubules
Mineralocorticoids
41
Treatment for Cushing syndrome
Glucocorticoid Inhibitor
42
inhibit synthesis of glucocorticoid PO
KETOCONAZOLE

FINALS PHARMA (5 decks)

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