topic 4 Flashcards
(92 cards)
What is a gene?
Section of DNA on a chromosome that controls a feature by coding for formation of one or more specific polypeptides or a functional RNA
Includes rRNA and tRNA
Define chromosome.
A thread-like structure made of protein and DNA by which hereditary information is physically passed from one generation to the next
What is chromatin?
The material that makes up chromosomes, consisting of DNA and the protein histone
What is an autosome?
A chromosome which is not a sex chromosome
What is the genetic code?
The sequence of triplets of nucleotides (codons) in DNA which determines the sequence of amino acids in an organism’s proteins
It is degenerate, non-overlapping, universal, and has start and stop codons
What does it mean that the genetic code is degenerate?
A single amino acid may be coded for by more than one triplet code
Explain non-overlapping in the context of the genetic code.
Each base appears in only one triplet – each base is only read once
What is meant by the genetic code being universal?
The genetic code is the same in all organisms, providing indirect evidence for evolution
What are histones?
Proteins that, together with DNA, make up the chromosomes of eukaryotic cells
Define chromatid.
Each of the two thread-like strands into which a chromosome divides, joined together by a single centromere prior to cell division
What is a locus?
The specific linear position of a particular gene on a certain chromosome
What are alleles?
Alternative forms of a particular gene with different base sequences, and therefore different codes
Define protein synthesis.
The process by which the genetic code codes for proteins in the cell, involving transcription and translation
What is a genome?
The complete set of genetic material present in a cell or an organism
What is the human genome?
The complete set of genes in a cell, including those in mitochondria and/or chloroplasts
Define proteome.
The full range of proteins produced by the genome, sometimes referred to as the complete proteome under specific conditions
What is transcription?
Formation of messenger RNA molecules from the DNA that makes up a particular gene; the first stage of protein synthesis
What enzyme is responsible for joining nucleotides to form mRNA during transcription?
RNA Polymerase
What are nucleotides?
Complex chemicals made up of an organic base, a sugar, and a phosphate; the basic units of nucleic acids DNA and RNA
What is mRNA?
The type of RNA that is a long strand arranged in a single helix, with its base sequence determined by a length of DNA
Define triplet.
A sequence of three bases in DNA
What is the template strand?
The strand of DNA used during transcription to make mRNA, running in a 3’ to 5’ direction
What is a codon?
A sequence of three adjacent nucleotides in mRNA that codes for one amino acid
What is an intron?
Portions of DNA within a gene that do not code for a polypeptide and are removed from pre-mRNA after transcription