Toxicology Flashcards
(11 cards)
What is Toxicology?
The study of toxins. They can either be synthetic or naturally occurring
Acute response
Immediate response to a single, high level of exposure.
Example: electric shock. You burn your hand when you touch fire
Chronic
Over time, slower, gradual, accumulating, long lasting effect from either a single exposure or repeated low level exposures
What factors determine exposure?
Solubility- is something dissolvable in oil or water?
For example, things that are solvable in oil persist for a long period of time. This is known as bioaccumulation
Levels will be biomagnified at higher food chain levels
Dosage
How much of something you are given. Danger in many occasions doesn’t come from just any exposure, we have to play attention to at what levels makes soemtjing dangerous
Bioaccumulate
The gradual accumulation of substances ( chemicals) in an organism. build up of chemicals
Biomagnification
the increase in concentration of chemicals in each organism up the food chain. Higher in the food chain = more chemicals
Rate of degradation
How long it takes for chemicals to break down
POPs- Persistent Organic Pollutants
Organic chemicals that degrade very slowly and therefore accumulate over time. They degrade slower than they accumulate
Ex: Perchlorate, Atrazine
Perchlorate
Waterborne contaminant from rocket fuel. Effects irrigation water and ultimately makes its way into breast milk
Atrazine
Most widely used herbicide in America that is an endocrine disruptor (HHA)