Toxicology Flashcards

(42 cards)

1
Q

What is the dilution dose for corrosive ingestion?

A

1-3 ml/lb milk or water

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2
Q

When is induced emesis contraindicated?

A

In horses, ruminants, rodents, rabbits, and birds

Depressed or comatose patients

Hyperactive patients

or patients that have already vomitted

Also if they have ingested any hydrocarbons

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3
Q

What is the dose hydrogen peroxide may be given to induce vomitting?

A

1 teaspoon per 5 lbs

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4
Q

What are some examples of emetic agents?

A

Hydrogen peroxide

Syrup of Ipecac

Apomorphine hydrochloride (injectable only)

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5
Q

How does activated charcoal work?

A

Absorb chemicals/toxins

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6
Q

What indicates the use of activated charcoal?

A

Organic poisons

Chemicals

Bacterial toxins

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7
Q

What contraindicates activated charcoal?

A

Ingestion of:

P- Pesticides

H- Hydrocarbons

A- Acids

I- Iron

L-Lithium

S-Solvents

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8
Q

What are cathartics?

A

Increase the clearing of intestinal content

Enhance the elimination of activated charcoal absorbed toxicant

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9
Q

When are cathartics contraindicated?

A

In patients that with diarrhea or dehydration

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10
Q

What are some common sources of household acids?

A

Toilet bowl cleaners, drain openers, metal cleaners, antirust compounds, gun cleaners, battery fluids, sanitizers

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11
Q

What are some sources of household alkalines?

A

Drain openers, oven cleaner, bleaches, denture cleaners, cement

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12
Q

What pH can cause esophogeal ulcers?

A

pH 12.5

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13
Q

What pH can cause esophogeal perforation?

A

pH >14

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14
Q

What are some signs of essential oil ingestion?

A

GI and mucous membrane irritation, CNS depression, skin irritation

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15
Q

What are some severe signs of cationic detergent ingestion?

A

Redness of skin, tissue swelling, intense pain, ulceration

Tissue necrosis and inflammation of the mouth, stomach and esophagus

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16
Q

What are the first signs of nicotine ingestion? (Usually can be seen within 15 - 45 mins)

A

Excitation, tachypnea, salivation, emesis, and diarrhea

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17
Q

After the initial signs of nicotine ingestion what symptoms can be seen?

A

Muscle weakness, twitching, depression, shallow respiration, collapse, coma and cardiac arrest

18
Q

Napthalene, an active ingredient in mothballs can cause what?

A

Heinz bodies and hemolysis

19
Q

Paradichlorobenzene, an active ingredient in mothballs affect what?

A

Affect liver and CNS

20
Q

Tremorgenic mycotoxins are found on what?

21
Q

What plant species can cause cardiovascular dysfunction?

A

Rhododendrons/Azaleas

22
Q

When are clinical signs of Rhododendron sp. ingestion seen?

A

4-12 hours after ingestion

23
Q

Cardiac glycoside containing plants:

A

Lilly-of-the-valley, Foxglove, oleander

24
Q

Ingestion of one or more seeds has resulted in liver failure and death in dogs

A

Cycad/Sago Palms

25
Toxin found in Cycad/Sago Palms
Cycasin Toxin
26
What is the toxic portion of Castor beans?
Ricin
27
Calcium Oxalate containing plants
Calla lily, elephant ear, dumb cane, pathos, mother-in-law's tongue
28
Highly toxic insecticide found in fly bait
Methomyl
29
Most obvious sign of fly bait ingestion
Seizures
30
Toxin found in slug and snail bait
Metaldehyde
31
Toxin found in gopher or mole bait
Zinc phosphide
32
Systemic insecticides contain Disulfoton or Disyston, or _________ which are highly toxic
Organophosphate
33
3 main types of mouse/rat bait
Anticoagulant, Bromethalin, Cholecalciferol
34
What is the treatment of Bromethalin or Cholecalciferol ingestion?
Aggressive decontamination - Repeated doses of activated charcoal
35
Formaldehyde can cause _____ \_\_\_\_\_\_ if significant quantities are ingested
Metabolic acidosis
36
3X less toxic than ethylene glycol
Propylene glycol
37
Most dangerous form of antifreeze
Ethylene glycol
38
Minimal lethal dose of ethylene glycol in dogs and cats
Dogs - 4.4-6.6 ml/kg Cats- 1.4 ml/kg
39
Ethylene glycol ingestion causes what?
Metabolic acidosis Renal failure
40
When is the peak level of ethylene glycol ingestion seen?
1-4 hours
41
False positive results of ethylene glycol ingestion occur from what?
Activated charcoal and injectable meds
42
Preferred treatment of ethylene glycol for dogs?
Fomepizole