TRANS 076 Psychogenic Drugs Flashcards

(74 cards)

1
Q

GTCS ( GRAND MAL EPILEPSY ) DOC

A
Levetiracetam
• 250-500-1000 mg. tablet.
• 100mg./mL. injection
Lamotrigine
• 25-100-200 mg. tablet
Phenytoin
• 30-100 mg. capsule
• 30mg./ 5mL. susp.
• 50 mg./mL. ampule IV

LLP

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2
Q

TRIGEMINAL NEURALGIA DOC

A

Carbamazepine
• 200-400 mg. tablet
• 100 mg./5mL. syrup

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3
Q

FEBRILE CONVULSION( CHILDREN ) DOC?

A

Phenobarbital
• 15-30-60-90 mg. tablet
• 130mg./mL IV/IM

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4
Q

NEUROPATHIC PAIN / POST-HERPETIC NEURALGIA

A

Gabapentin

• 100-300-400 mg. capsule

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5
Q

SMEI (SEVERE MYOCLONIC EPILEPSY IN INFANCY –

DRAVET’S S.)

A
Stripentol
• 250-500mg. capsule
Valproate Na
• 250 mg. tablet
• 250mg./ 5mL. syruo
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6
Q

LENNOX-GASTAUT’S SYNDROME

A
Lamotrigine
• 25-200 mg. tablet
Topiramate
• 25-200 mg. tablet
• 15-25 mg. capsule
Rufinamide
• 200-400mg. tablet
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7
Q

ABSENCE EPILEPSY (PETIT MAL )

A
Ethosuximide
• 250 mg. capsule
• 250 mg./ mL. syrup
\+ Valproate Na
• 250 mg. tablet
• 250 mg./5 mL. syrup
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8
Q

EPILEPSY IN PREGNANCY AND MENSTRUATION

A

Acetazolamide
• 250 mg. tablet
• 500 mg. capsule

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9
Q

STATUS EPILEPTICUS

A

Diazepam

• 5 mg./ mL. IV PUSH (20-30 mg.) @ 15 MIN.

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10
Q

INFANTILE SPASM

A

Clonazepam
• 2 mg. tablet
Clobazam
• 15-25 mg. tablet

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11
Q

MEDICAL / SITUATIONAL INSOMNIA

A

Zolpidem
• 10 mg. tablet
Eszopiclone
• 1-2-3 mg. tablet

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12
Q

GERIATRIC INSOMNIA

A

Triazolam

• 0.125- 0.25 mg. tablet

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13
Q

ANXIETY NEUROSIS

A

Buspirone

• 5 – 10 -15 – 30mg. tablet

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14
Q

OVERDOSE TOXICITY OF BENZODIAZEPINES

A

Flumazenil

• 100mcg./mL. ampule IV

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15
Q

METHANOL TOXICITY

A

Ethanol/ Fomepizole

• 1mg./mL. vial IV

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16
Q

FEMORAL TO POPLITEAL BY-PASS SURGERY

CARDIOVASCULAR RISKS

A
Propofol
• 10 mg./mL.
• 20-50mL. vial / ampule. IV
\+ Fentanyl
• 50mcg./mL. ampule IV
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17
Q

OPD MINOR SURGERY

A

Ketamine

• 50mg./mL. vial IM/IV

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18
Q

MAJOR SURGERY ( NO CARDIOVASCULAR RISKS)

A

Isoflurane
• 100-250mL. bottle
Enflurane
• 250mL. bottle + N20 GAS

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19
Q

PRE-MEDICATION ( SKELETAL MUSCLE RELAXATION)

A
Succinylcholine
• 20 mg/mL IV
Rocuronium
• 10 mg/mL
• 2.5-5-10ml. amp. IV
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20
Q

SPINAL ANESTHESIA (KNEE ARTHROPLASTY)

A

Bupivacaine 0.5%

• 5-10mL amp. per vial local inf. (No cardiotoxicity )

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21
Q

SPINAL ANESTHESIA ( WITH CARDIOTOXICITY )

A
Lidocaine
• 1-2% 5-50. vial local inf.
• 5% ointment,
• 10% spray
• 4% topical solution
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22
Q

LOCAL ANESTHESIA FOR BURN WOUNDS

A
Benzocaine
• 6% cream
• 20% gels
• 20% ointment
• 0.8% lotion
• 20% spray
• 20% liquid
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23
Q

IV CATHETERIZATION PRIOR TO VENIPUNCTURE

A

EMLA (Lidocaine + Prilocaine)

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24
Q

MPTP-INDUCED PARKINSONISM

A

Rasagiline

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25
PATHOLOGIC PARKINSONISM
``` Pramipexole (D3) • 0.125 – 1.5mg tablet • 0.375 – 4.5mg. ER tablet Ropinirole (D2) • 0.25 – 5mg tablet., • 2- 12 mg. ER tablet ```
26
STAGE-FRIGHT TREMOR
Propranolol | • 10-40-80mg tablet or capsule
27
HUNTINGTON’S DISEASE
``` Haloperidol • 500mcg.-1.5 – 2 – 5 –10 -20mg. tablet • 5mg./mL. ampule IM Olanzapine • 5-10mg. tablet • 10mg. vial IM ```
28
SYDENHAM’S CHOREA
No Treatment D2-Blocker Symptomatic – O FLUPHENAZINE • 25mg./mL. ampule/vial IM/SC
29
TICS (GILLES DE LA TOURETTE’S SYNDROME)
``` Haloperidol • 500mcg. • 20mg. tablet Pimozide • 1-2mg. tablet Clonidine • 75-150mcg. tablet ```
30
RESTLESS LEG SYNDROME
Pramipezole • 0.125 -4.5mg. tablet Ropinirole • 0.25 – 12mg. tablet
31
WILSON’S DISEASE
N-Acetyl-Penicillamine | • 25mg./ bottle crystals PO
32
The most common psychotic illness
SCHIZOPHRENIA
33
* D2/5-HT2 | * Block dopamine 2 more than serotonin 2
Phenothiazines
34
examples of Phenothiazines
Chlorpromazine Thioridazine Fluphenazine Thiothixene
35
Causes these effects: type of Phenothiazines
Thioridazine
36
Type of Phenothiazines that causes tardive dyskinesia
Fluphenazine
37
Haloperidol, Risperidone, MISC: what drug classs?
Butyrophenone
38
o Very potent drug with a high incidence of extrapyramidal side effect o Parkinsonism: most common AE
• Haloperidol
39
best drug among the new atypical drug
Clozapine
40
causes Hypotension | • Hyperprolactinemia
Risperidone
41
causes • QT prolongation on ECG which leads to ventricular arrhythmia
Ziprasidone
42
causes • Weight gain • Hyperglycemia • Hypercholesterolemia • No agranulocytosis
Olanzapine
43
o Block histamine 1 producing hypotension,
Queiapine
44
o Prolonged QT which leads to ventricular arrhythmia
• Ziprasidone
45
• Most novel among the new/atypical drug (Academically
Dihydrocarbostyril
46
- Life-threatening due to hypersensitivity to extrapyramidal side effect characterized by muscle rigidity and hyperthermia - Treatment: diazepam, dantrolene, bromocriptine, diphenhydramine (BEST) hyperthermia: cooling
▪ Neuroleptic malignant syndrome (NMS)
47
* Best stabilizer for mania (drug of choice) * Toxic drug, less potent, high dose * Block enzyme GSK-3, IP3-IP2-IP1 + DAG, PGMut * Teratogenic: Ebstein’s Anomaly of the heart (Category D)
Lithium CO3
48
Combination of the best drugs for Bipolar Disorder
• Olanzapine + Fluoxetine + Quetiapine
49
Li+-Induced Diabetes Insipidus: DOC is
Amiloride
50
* Inhibits reuptake of norepinephrine and serotonin (NET, SERT) * Class 1A Anti-arrythmia
Tricyclics (TCA)
51
* Anti-Ach | * 2ND DOC for Major Depression
Amitryptiline
52
what drug class?
ANTI-SEROTONIN/5HT2-MODULATORS
53
* ADHD in children (Secondary) * DOC for cigarette smoking cessation * Seizures 2nd: * Obesity/Weight loss * Block reuptake of Dopamine 3+ transporter
Bupropion
54
* Norepinephrine and serotonin transporter are inhibited (NET/SERT) * DOC for depression and neurologic pain * Fibromyalgia: pain in the muscle
SSNRI
55
* 1ST DOC in MDD * Anxiety * ADR: Premature Ejaculation, Bulimia
SSRI (SELECTIVE-5HT-REUPTAKE-INHIBITORS)
56
* The best/ No. 1 SSRI | * PMDD / Bulimia Nervosa
Citalopram / Escitalopram | Fluoxetine
57
* 3RD DOC for MDD | * ADR: HPN Crisis, Serotonin syndrome
MAO-A/B-INHIBITORS
58
what drug class • Phenelzine /Isocarboxazid
MAO - A
59
what drug class? | • Selegiline
Selegiline
60
Anorgasmia is seen in what drug?
Tranylcypromine
61
SSRI adverse effect?
o Loss of sexual f. Libido, arousal, orgasm
62
SNRI: adverse effect?
o HPN and cardiotoxicity
63
o Sedation o Priapism o Hepatic failure (Nefazo) which adverse effects
5HT2 - M
64
o Parkinsonism (Amoxapine) which adverse effects?
Tetra./Uni.:
65
which adverse effect? o Sexual anorgasmia o Confusion o Delirium w/ psychosis o Amphetamine-like effects.
MAOI:
66
o Serotonin Syndrome, HPN CRISIS o STROKE, M.I. which adverse effect?
SSRI+MAOi
67
BULEMIA NERVOSA DOC?
Fluoxetine
68
OCD (OBSESSIVE-COMPULSIVE DISORDER )
CLomipramine
69
SAD (SOCIAL ANXIETY DISORDER )
Venlafaxine
70
CHRONIC PAIN DISORDER (FIBROMYALGIA)
Milnacipran
71
PMDD ( PRE-MENSTRUAL DYSPHORIC DISORDER )
Sertraline
72
SMOKING CESSATION
Buproprion
73
ENURESIS IN CHILDREN
``` Imipramine • 25-50mg. tablet • 75-150mg. capsule Duloxetine • 20-50mg. capsule ```
74
SEDATION – HYPNOSIS IN MDD
Trazodone