Transcription Flashcards
(19 cards)
Mendelian Genetics Definition
Distinct unit of heredity
molecular definition
unique combination of DNA bases that provide instructions for making a protein
promoter
transcription initiation site
terminator
stops transcription
operon
cluster of genes controlled by one promoter
open reading frame
region that is transcribed
exons
protein coding sequences
introns
non coding sequencees
transcription
nucleotide to nucleotide
mRNA
RNA that contains the information for the synthesis of a particular polypeptide
Steps of mRNA transcription
initiation, elongation, termination
transcription unite
stretch of DNA that is transcribed
promoter
DNA sequence where RNA polymerase attaches
template strand
one of the two DNA strands serves as template for RNA synthesis
elongation
RNA polymerase untwists the double helix, moves along DNA adds nucleotides to the 3’ end of growing RNA molecule
Termination
- occurs at polyadenylation signal sequence in eukaryotes
- terminates at terminator (hairpin structure) in bacteria
RNA modification
needed in eukaryotes before mRNA translates into protein
Splicing
introns are later removed or excised and exons are connected or spliced
Spliceosome
large molecular complex made of several proteins and non-coding RNA
- removes introns and joins together exons