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Acute Care in OT > Transplant > Flashcards

Flashcards in Transplant Deck (14):
1

What is the definition of death for the organ procurement process?

1. irreversible cessation circulatory & respiratory function
2. irreversible cessation of all functions of entire brain, including brainstem

2

allograft (homograft)

from the same species, non identical

3

isograft (syngeneic)

identical twin

4

autograft transplant

tissue transplanted from one site to another

5

xenograft (heterograft)

between two species

6

How long can the:
heart & lungs
kidney
liver
survive outside body?

Heart & lungs - 4 - 6 hours
Kidney - 36 - 48 hours
Liver - 12 - 15 hours

7

Host Vs. Graft

host attacks organ being put in
- most types of rejection are this

8

Graft vs. Host

more common with hematopoietic transplant (b/c we put in immune system --> attacking host)

9

What is the order of strictness for protective precautions? (most strict --> least strict)

lung --> heart --> kidney/liver

10

After a hematopoietic cell transplant, how long is someone immuno-compromised?

6 months to 1 year

11

Innate Immunity

- "nonspecific"
- general type
- 1st line of defense
- regulation of inflammation
- > 90% of infections are controlled by this type of immunity
- fever & inflammation

12

Adaptive Immunity

- specific or acquired
- 2nd line of defense
- has a "memory"; refines and adjusts over lifetime of host
- humoral and cell-mediated

13

Colonization

microbes present in skin/mucous membrane without signs & symptoms of active infection

14

Neutropenia

low # of neutrophils in blood = higher risk for acquiring infections