Trials Flashcards
(33 cards)
Wiscops
All statins out come 23% better
TNT
High and low dose Lipitor high dose better
Ascot
20 mg Lipitor
Hps
Simvastatin study
Prove it
Pravachol inferior to Lipitor
Framingham risk
Age Gender Cholesterol HDL Smoking HTN Treating the HTN It under represents women and under estimates younger people risk
Asvd risk
CRP>2
Family history
ABI400
Courage trial
Pci superior to medical with angina
Excludes low EF recent pci and ongoing cp
Timac trial
High risk early intervention
Bari 2D
OMT and pci or CABG same for death
Aggressive diabetic no help
All hat
Chlorthalidone ace and ca blockers all equal.
Alpha blockers were dropped due to CHF
Accomplish
Norvasc/ benazapril vs benazapril/ hctz
Stopped as Norvasc limb was superior
Shep
Chlorthalidone less strokes
Athena study
Pallas study
Athena Dronedarone is superior to rate control
Less stroke
Pallas drone done increase death in CHF and permanent afib
Cogent trial
Plavix and omeprazole no difference
Comet study
Coreg reduces the effectiveness of dibutamine
Lopressor dies it only partially
Poise study
Routine use if beta blockers increase mortality
Stitch trial
People with low EF and cad
CABG did not reduce mortality
Only Lima to lad helpful
Viability useless
Vheft
Blacks and CHF
Do better with hydralazine and nitro
Rales and epsesius
CHF trial rales about aldactone
Epsesius about eplerimone
Both reduce death by30% but start acei first
Plato
Ticagrelor better than plavix
Triton timi38
Prasugrel better than plavix
Freedom
CABG vs DES in DM
Higher death CVA mi 14% mi in pci vs 6% CABG Stroke is higher with CABG Higher repeat with pci With low scores they are identical
Syntax
1year higher repeat vascularization for pci
Pci was reasonable in unprotected left main in low syntax scores
Over 22 CABG over pci
Stokes higher low syntax
Over 22 higher tia and mi in pci
Over all MACCE higher for pci