Tricyclic Antidepressants Flashcards

(25 cards)

1
Q

What are tricyclic antidepressants primarily used to treat?

A

Depression

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2
Q

True or False: Tricyclic antidepressants can also be effective for anxiety disorders.

A

True

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3
Q

Fill in the blank: Tricyclic antidepressants work by inhibiting the reuptake of __________ and __________.

A

norepinephrine, serotonin

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4
Q

Name one common tricyclic antidepressant.

A

Amitriptyline

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5
Q

What is a major side effect associated with tricyclic antidepressants?

A

Dry mouth

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6
Q

Multiple Choice: Which of the following is NOT a tricyclic antidepressant? A) Nortriptyline B) Fluoxetine C) Doxepin D) Imipramine

A

B) Fluoxetine

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7
Q

Short Answer: What is the mechanism of action of tricyclic antidepressants?

A

They block the reuptake of norepinephrine and serotonin.

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8
Q

True or False: Tricyclic antidepressants have a rapid onset of action.

A

False

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9
Q

What is the risk of overdose with tricyclic antidepressants?

A

High risk of serious cardiac arrhythmias

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10
Q

Fill in the blank: Tricyclic antidepressants can cause __________, which is characterized by weight gain and sedation.

A

anticholinergic effects

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11
Q

Name one condition other than depression that tricyclic antidepressants can treat.

A

Chronic pain

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12
Q

Multiple Choice: Which tricyclic antidepressant is often used for migraine prophylaxis? A) Amitriptyline B) Paroxetine C) Sertraline D) Escitalopram

A

A) Amitriptyline

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13
Q

True or False: Tricyclic antidepressants are often the first-line treatment for depression.

A

False

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14
Q

What is one contraindication for using tricyclic antidepressants?

A

Recent myocardial infarction

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15
Q

Fill in the blank: The therapeutic effects of tricyclic antidepressants may take __________ weeks to become noticeable.

A

2 to 4

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16
Q

Short Answer: Why are tricyclic antidepressants not commonly prescribed as first-line treatment?

A

Due to their side effects and risk of overdose.

17
Q

What class of drugs do tricyclic antidepressants belong to?

A

Antidepressants

18
Q

Multiple Choice: Which of the following is a side effect of tricyclic antidepressants? A) Increased libido B) Constipation C) Insomnia D) Weight loss

A

B) Constipation

19
Q

True or False: Tricyclic antidepressants can interact with other medications, increasing the risk of side effects.

20
Q

Fill in the blank: Tricyclic antidepressants are often referred to as TCA, which stands for __________.

A

tricyclic antidepressants

21
Q

What is the role of the neurotransmitter serotonin in the effectiveness of tricyclic antidepressants?

A

Serotonin reuptake inhibition contributes to mood elevation.

22
Q

Multiple Choice: Which tricyclic antidepressant is known for its sedative properties? A) Desipramine B) Amitriptyline C) Nortriptyline D) Clomipramine

A

B) Amitriptyline

23
Q

True or False: Tricyclic antidepressants are safe for use during pregnancy.

24
Q

What is the effect of tricyclic antidepressants on the cardiovascular system?

A

They can cause orthostatic hypotension.

25
Fill in the blank: Tricyclic antidepressants can cause __________, which is a condition characterized by a prolonged QT interval on an ECG.
cardiac arrhythmias