trypanosoma Flashcards

(76 cards)

0
Q

trypansomes are intercellular except _____________ which is intracellular

A

T. cruzi

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1
Q

trypanosome occur in _________ & _________

A

blood

tissue fluids

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2
Q

T. cruzi is found where?

A

cells of RE system

cardiace muscles

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3
Q

disease produced by trypanosomes

A

trypanosomiosis

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4
Q

transmission occurs by blood sucking parasites except __________

A

T. equiperdum in equines (by coitus)

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5
Q

transmission can be _______ or ________

A

cyclical

non-cyclical

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6
Q

cyclical transmission can occur by twi ways

A

anterior station development(foregut)

posterior station development(hindgut)

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7
Q

anterior station development occurs in __________ of insect and infection of __________is tranmitted fly bite

A

proboscis and salivary glands

trypomastigote(infective stahe)

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8
Q

parasites transmitted by posterior station are non pathogenic TRUE or FALSE

A

TRUE

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9
Q

give example of ANTERIOR STATION TRANSFER

A

T. congolense
T. vivax
t. brucei

they are transmitted by TSE TSE fly

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10
Q

give an example of POSTERIOR STATION DEVELOPMENT

A

T. theileri(tabanid flies)
T. melophagium(melophagus ovinus/sheep ked)
T. cruzi(reduviid bug)

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11
Q

mechanical transmission is also known as

A

non-cyclical transmission

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12
Q

example of mechanical transmission

A

T. evansi(biting flies)

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13
Q

in well developed trypanosomal infection in vertebrates, the surface antigens change every few _______

A

days

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14
Q

full form of VAT

A

variant antigen type

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15
Q

heavy antigen coating is found on surface of ___________ only

A

trypomastigote

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16
Q

only __________ stage of trypanosome is responsible for antigenic changes

A

trypomastigote

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17
Q

the surface coat is made up of __________ identical glycoprotein molecules

A

10 lakh

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18
Q

these identical glycoprotein molecules are known as _______

A

VSG

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19
Q

enumerate VSG

A

variant suface glycoprotein

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20
Q

under what conditions, glycoprotein coat of trypanosome is lost

A
  • after entering VECTOR(either cyclical or mechanical)

- during IN VITRO culture

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21
Q

the immunological response of host to salivarian & stercorarian trypanosome is different TRUE or FALSE

A

TRUe

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22
Q

Salivarian trypanosomes produce _______ parasitemia in host

A

ascending

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23
Q

the immune response againt Salivarian tryoanosomes is mediated by ______ & ______ antibodies

A

IgG

IgM

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24
first trypanosome shown to be pathogenic to mammals
T. evansi
25
first parasitic protozoa observed in microscope
Eimeria stiedae
26
T. evansi was identified by _______
griffith evans
27
diseases caused by T. evansi
surra tibersia gufar
28
vector of T. evansi
tabanid flies & other blood sucking arthropods
29
forms lacking kinetoplast arise after _________
drug treatment
30
T. evans does not survive in the proboscis of flies for more than _____ minutes
10-15
31
the most common clinico-pathological findings in T. evansi infection is ______________
progressive anaemia
32
causes for progressive anaemia
haemolysins immunoglobulin antigen complex on RBC depression of erythropoiesis
33
in T. evansi infection ____________ is considered to be cause of death
hypoglycemia
34
hypoglycemia occurs due to direct utilisation of glucose by T. evansi TRUE or FALSE
FALSe
35
why hypoglycemia occurs in T . evansi infection?
metabolism of carbohydrate is disturbed due to malfunction of adrenals,pancreas and thyroid
36
in T. evansi infection in horse, the main symptoms are
``` intermittent fever(rising to 44 C) anaemia ```
37
in T. evansi infection in horses, petechial haemorrhages area seen on
mucuous membreane of eye | vulva of mare
38
in T. evansi infection of horses, urine becomes _________ in color _________ tinged mucous discharge from nostrils plasma takes _______ tinge
dark yellow yellow red
39
in T. evansi infection of horse, __________ accompanies febrile paroxysm(fever burst)
urticarial eruptions(on neck,flank)
40
__________ species is considered to be main reservoirs of T. evansi infection in horse
Cattle & buffalo
41
buffalo have higher incidence rate of T. evansi infection than Cattle TRUE or FALSE
TRUE
42
in acute disease of T. evansi, death occurs in ______ hours in cattle & buffalo
6-12
43
in T. evansi infection of Cattle & buffalo, temperature rise is seen upto ______
40.6 C | 44 C is horse
44
in PERACUTE cases of T. evansi infection of Cattle & buffalo, nervous signs develop in ______hours
2-3
45
in T. evansi infection of Cattle & buffalo, BILATERAL LACRIMATION is seen in 1. peracute 2. acute 3. subacute 3. chronic
subacute & chronic
46
surra means
rotten
47
T. evansi was first seen in ________
camel
48
T. evansi infection in camel is known as _______
tibersia
49
tibersia means
3 year duration
50
main character of T. evansi infection in camel
hump disappears
51
main character of SURRA in dogs & cats
voice of dog changes, similar to RABIES
52
why does voice changes in SURRA in dog & cat
oedema of larynx
53
T. evansi is not pathogenic to _______ species
PIG
54
blood smears taken at peak of fever are ________(+ve/-ve)for parasite
positive
55
arrange the parasite in decresing order of size evansi theileri equiperdum
theileri>evansi>equiperdum
56
____________ are most suitable hosts for detcting subpatent T. evansi infection
albino mice & rat(DOG for T. equiperdum)
57
in white mice, ______ ml of blood is inoculated intra_________
0.5 | intraperitoneally
58
drugs for treatment of trypanosomiosis
quinpyramine suramin diamidine phenanthridine
59
difference of T. equipardum from t. evansi
smaller size | lesser motility
60
disease caused by T. equiperdum
dourine equine syphilis breeding paralysis
61
dourine means
dirty
62
T. equiperdum is transmitted by
coitus
63
clinical dourine has ___ phases
3
64
name the 3 phases of dourine
1. phase of OEDEMA 2. URTICARIAL phase 3. phase of PARALYSIS
65
aobrtion occur in which phase of dourine
1st i.e. phase of OEDEMA
66
pathogonomic lesion of dourine are
dollar spot
67
dollar spots are seen in which phase of dourine
2nd i.e. 7 | URTICARIAL phase
68
in phase of paralysis in dourine, the effected parts are
hind legs lips nostril ears
69
________ is most suitable host for detecting T . equipardum infection
dog
70
largest species or genus Trypanosoma
T. theileri
71
in T. theileri infection , which forms of parasite occur in blood?
trypomastigote | epimastigote
72
T. theileri is trasmitted __________ in __________ station of ________ flies
cyclically posterior tabanid
73
T. theileri is associated with _________ disease
turning sickness
74
diagnosis of T. theileri
by cultivation of trypanosomes on NNN
75
NNN stands for
Novy McNeal Nicolle