Tumour classification and nomenclature Flashcards Preview

EMS - Mechanisms of disease > Tumour classification and nomenclature > Flashcards

Flashcards in Tumour classification and nomenclature Deck (22):
1

For benign epithlial tumours, what is the first division with regards to classification?

Surface (non-glandular/non-secretory) -> papilloma

Glandular (secretory) -> adenoma

2

How may benign epithelial tumours of the surface (non-gladular/non-secretory) be further classified?

Name of CELL TYPE of origin -> (e.g. SQUAMOUS CELL)
e.g. squamous cell papilloma.

3

How may benign epithelial tumours of the gladular/secretory tissues be further classified?

Name of GLANDULAR TISSUE of origin -> (e.g. COLONIC)
e.g. pancreatic cystadenoma

4

What name is given to malignant epithlial tumours.

Carcinomas

5

How would you name a malignant epithelial tumour of surface origin?

By prefixing CARCINOMA with the cell of origin.
e.g. squamous cell carcinoma

6

How would you name a malignant epithelial tumour of glandular origin?

Adenocarcinoma

7

What name would be given to a benign tumour derived from the basal cells of the skin?

Basal cell papilloma

8

What name would be given to a benign tumour derived from the transitional cells of the bladder?

Transitional cell papilloma

9

What name would be given to a benign tumour derived from liver cells?

Liver cell adenoma

10

What name would be given to a malignant tumour derived from glandular epithelia of the colon?

Colonic adenocarcinoma

11

What name would be given to a malignant tumour derived from basal cells of the skin?

Basal cell carcinoma

12

How would you name a benign mesenchymal tumour?

With the suffix -oma preceded by the prefix for the tissue or cell of origin.
e.g. rhabdomyoma - benign tumour of skeletal muscle

13

How would you name a malignant mesenchymal tumour?

With the suffice -sarcoma preceded by the prefix for the tissue or cell of origin.
e.g. rhabdomyosarcoma

14

What are the prefixes for the following mesenchymal tissues?

Smooth muscle
Skeletal muscle
Fibrous tissue
Bone
Cartilage
Blood vessels
Adipose tissue

Leiomyo-
Rhabdomyo-
Fibro-
Osteo-
Chondro-
Angio-
Lipo-

15

What name is given to a benign tumour of the melanocytes?

Melanocytic nevus

16

Give examples of malignant tumours that defy the usual naming conventions.

Melanoma
Leukemia
Lymphoma
CNS neoplasms (e.g. GBM, astrocytoma)

17

What are germ cell tumours?

Common in - gonads
Cells arise from germ cells.

e.g. seminoma, teratoma

18

What are embryonal tumours?

Occur in very young

19

Is a pleomorphic salivary adenoma benign or malignant?

Benign

20

Where might you find a carcinosarcoma?

Ovaries

21

What is a hamartoma?

- Non-neoplastic overgrowth of normal tissue
- Indigenous to the site of occurrence
- Developmental abnormalities
- Lung hamartoma

22

What is a choristoma?

AKA Heterotropic rests
Nodules of organ parenchyma in another organ
E.g. normal (non-neoplastic) pancreas nodule in stomach