Tx of LRTI Flashcards

(33 cards)

1
Q

How long does acute bronchitis take to resolve?

A

1-3 weeks. Symptoms are self-limited

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2
Q

Non-pharmacological Tx of acute bronchitis

A

Nonpharmacologic options for cough relief such as throat lozenges,
hot tea, honey, steam inhalation, adequate hydration and/or smoking
cessation or avoidance of second-hand smoke is a reasonable first
step.

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3
Q

3 types of cough preparations

A

Antitussives
Mucolytics
Expectorants

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4
Q

What should you exclude in a pt with acute bronchitis?

A

Exclude underlying bronchiectasis or acute exacerbation of chronic bronchitis

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5
Q

What are the signs and symptoms of acute on chronic bronchitis? (5)

A

wheeze
* breathlessness
* tightness of the chest
* respiratory distress
* cough

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6
Q

T/F bronchospasm is fully reversible with COPD

A

F. It is partially reversible

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7
Q

Explain the Mx of acute exacerbations of chronic bronchitis

A
  1. Regular doses of short acting bronchodilators (SABA, SAMA)
    -short acting muscarinic agonist
  2. Supplemental Oxygen (24-28%)
  3. Oral corticosteroids: Prednisone, PO, 30mg daily for 5 days
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8
Q

What is the management of acute INFECTIVE exacerbation of chronic bronchitis?

A

Amoxicillin, oral, 8 hourly for 5 days.
Doxycycline PO for 5 days if severe pen allergy.
(Pt must take full glass of water when taking Doxycyclin)

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9
Q

Name two structures of Influenza found that are important in influenza

A

It is has neuraminidase and haemagglutinin

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10
Q

Name 2 drugs that act as Neuraminidase inhibitors?

A

Oseltamivir
Zanamivir (Inhalor formulation)

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11
Q

When should Oseltamivir Tx be initiated?

A

Initiate tx within 24-48 hours of onset of symptoms reduce duration by less than 1 day

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12
Q

List pt groups that are high risk for influenza

A

Pregnant women
Immunocompromised children <2

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13
Q

Who is eligible for influenza PEP?

A

PEP only for high-risk close contacts (within 48 hours of exposure)

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14
Q

Adverse effects of Oseltamivir

A

N&V (report of fatal neuropsychiatric AEs)

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15
Q

How is the influenza vaccine formulated?

A

2 strains from influenza A and 1 or 2 strains from Influenza B

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16
Q

Who is eligible for the influenza vaccine? (6)

A

-Pregnant women
-HCWs
-HIV+ pts
-Elderly (>65yrs)
-Residents of Old age homes
-Chronic care facilities

17
Q

How long does the vaccine take to become effective?

A

Takes 2-3 weeks

18
Q

AEs of influenza vaccine

A

uncommon, myalgia, fever, headache and nausea

19
Q

Contraindications of influenza vaccine

A

known hypersensitivity to egg protein

20
Q

In the treatment of Covid-19, Which drug is recommended for pts requiring supplemental O2 or on mechanical ventilation

A

Dexamethasone

21
Q

Which drug is recommended for venous thromboembolism prophylaxis dosing is
recommended for all hospitalised patients?

22
Q

Which drug is recommended for pts requiring only supplemental oxygen+

23
Q

What is the vital signs criteria for mild covid-19 infection?

A

SpO2≥95% on room air
* Respiratory rate <25
* Heart rate <120
* Temp 36-39°C
* Mental status normal

24
Q

What is the vital signs criteria for severe covid-19 infection?

A
  • Breathless at rest or while talking
  • Respiratory rate ≥ 25
  • BP < 90/60
  • Pulse rate > 120
  • Confused or agitated
  • Unable to walk without help
  • Oxygen saturation < 95%
  • Coughs ≥ 1 tablespoon fresh blood
25
What are the signs of tension pneumothorax?
* Sudden breathlessness, more resonant/decreased breath sounds/pain on 1 side, deviated trachea, BP < 90/60: tension pneumothorax likely
26
What medications need to be given to COVID patients?
Analgesics & Antipyretics Thromboprophylaxis Corticosteroids
27
What analgesic medication should you give to a patient with covid-19?
Paracetamol is more recommended than NSAIDs
28
List corticosteroids options recommended for pt with covid and are on supplemental O2. Give dosage instructions and duration of use as well. (5)
Dexamethasone 6mg daily for 10 days * OR * Betamethasone 6mg (po/iv) for 10 days * OR * Prednisone 40mg PO daily for 10 days * WHO recommended equivalents * OR * Hydrocortisone 50 mg IV TDS * OR * Methylprednisolone 8 mg QID or 16 mg BD PO or IV
29
List medications that can can be used for thromboprophylaxis in pts with COVID-19
Unfractionated heparin Low molecular weight heparin (Dalteparin and enoxaparin)
30
Give 2 side effects of heparins
Bleeding, heparin induced thrombocytopenia (HIT)
31
What is the MOA of heparins?
Inactivates thrombin & factor Xa through antithrombin III activation
32
Dosage of enoxaparin for hospitalized pts?
40mg SC daily
33
What is the dosage of unfractionated heparin in hospitalized patients?
5000 units SC 12 hourly