Uensbe Flashcards
(28 cards)
Anticoagulant or Procoagulant
tPA (tissue plasminogen activator) =
Anti-coagulant (promotes fibrinolysis)
Anticoagulant or Procoagulant
Thrombomodulin =
Anti-coagulant (activates protein C, which inactivates factors Va and VIIIa)
Anticoagulant or Procoagulant
Anti-coagulant (activates protein C, which inactivates factors Va and VIIIa)
Thrombomodulin
Anticoagulant or Procoagulant
TAFI (Thrombin-Activatable Fibrinolysis Inhibitor) =
Pro-coagulant (inhibits fibrinolysis)
Anticoagulant or Procoagulant
PAI (Plasminogen Activator Inhibitor) =
Pro-coagulant (inhibits tPA and uPA, blocking fibrinolysis)
Anticoagulant or Procoagulant
Fibrinogen =
Pro-coagulant (precursor to fibrin, essential for clot formation)
Other name
I
Fibrinogen
Other name
II
Prothrombin
Other name
III
Tissue Factor (TF) / Thromboplastin
Other name
IV
Calcium ions (Ca²⁺)
Other name
VIII
Anti-hemophilic Factor A
Other name
IX
Christmas Factor / Anti-hemophilic B
Other name
X
Stuart-Prower Factor
Other name
XI
Plasma Thromboplastin Antecedent (PTA)
Other name
XII
Hageman Factor
Other name
XIII
Fibrin-Stabilizing Factor
Other name
V
VII
Labile Factor
Stable Factor
Other name
Prekallikrein
_________
Fletcher Factor
Other name
HMWK
Fitzgerald Factor
Vitamin K–dependent;
inactivates Factors Va and VIIIa (with Protein S)
Protein C
Also called Christmas Factor; part of intrinsic pathway
FIX
Factor I; converted by thrombin to fibrin, forms the clot mesh
Fibrinogen
Product of fibrin degradation;
indicates recent clot formation and breakdown
D-Dimer
Bleeding Time (BT)
Clotting Time (CT)
Thrombomodulin (↑ activity)
Activates Protein C → anticoagulant effect
Normal
Increased
