unit 1 dosages

Question 2

Optimizing Cephalexin Dosing
* Usual dosage range:
* dependent on?
* Half-life:
* Excretion:
* Cellulitis dose
* Cystitis dose
* Suggests minimum of hours of subtherapeutic blood concentrations with Q12hr dosing

Answer 2

• Usual dosage range: 250 to 1,000mg every 6 hours or 500mg every 12 hours
• Time Dependent Drug: works best the longer concentrations stay above MIC
• Half-life: approximately 1-hour for adults
• Excretion: Urine 80-100% as unchanged drug in 6-8 hours
• Cellulitis: 500mg 4 times daily
• Cystitis: 500mg twice daily
• Suggests minimum 4-6 hours of subtherapeutic blood concentrations with Q12hr dosing

Question 3

Amoxicillin Pharmacokinetics
adult dosing immeadiate and extended release
all dosing based on which formula?
what timeframe for dosing is usually used?

Answer 3

8hrs usually used

Question 4

amoxicillin dosage for periodontitis

Answer 4

Question 5

augmentin and amoxicillin dosage

Answer 5

Question 6

reducing augmentin shits

Answer 6

Goal 14:1 ratio of amoxicillin to clavulanate to lessen this side effect
ideal: 600: Amoxicillin 600 mg /clavulanate 42.9mg per 5mL *

Question 7

amoxicillin dosing

Answer 7

Question 8

augmentin dosing

Answer 8

Question 9

kelfex Rx

Answer 9

RX: Cephalexin 500mg po QID x 5 days

Question 10

Cefuroxime rx

Answer 10

Cefuroxime 500mg po BID x 5 days

less doing with longer t1/2

Question 11

Metro DENTAL USES:
●Combined with? used when?
nickname
●Management of?
●Rx:

Answer 11

●Combined w/ -Lactams - 1st Line for serious orofacial
infections
 “poor man’s Augmentin”
●Management of refractory or progressive periodontitis.
●Rx: Metronidazole 500mg po Q8h x 5days, #15

Question 12

clindamyacin rx

Answer 12

Question 13

Low-dose systemic doxycycline for refractory agg. periodontitis
● dose

Answer 13

● Periostat™ (100 mg PO daily

Question 14

macrolide dosages
Orofacial Infection:
Perio Infection:

Answer 14

Orofacial Infection: 500mg, then 250mg PO Daily x 4 days.
Perio Infection: 500mg PO Daily x 5 days

Question 15

preffered prophylaxis dose

Answer 15

Amoxicillin 2gm X1 dose 30-60mins prior to dental procedure preferred

Question 16

AAOS Recommended Prophylaxis number one choice adult/child doses

Answer 16

Oral Amoxicillin
adult: 2g
child: 50 mg/kg

30-60 min before

Question 17

what if pt cannot take oral abx but no allergies?.

PJI prophylaxis

Answer 17

Ampicillin 2g IM or IV 50mg/kg IM or IV
OR
Ceftriaxone 1g IM or IV 50mg/kg IM or IV

Question 18

what if pt has a hx of penicillin allergies but can take oral abx (joint prophylaxis)

Answer 18

Cephalexin 2 g 50 mg/kg
OR
Azithromycin or clarithromycin 500 mg 15 mg/kg

Question 19

Allergic to penicillins and unable to take oral
medication for pji prophy

Answer 19

Ceftriaxone 1 g IM or IV 50 mg/kg IM or IV
OR
Azithromycin or clarithromycin 500 mg 15 mg/kg

Question 20

acyclovir preps for hsv
oral cap, tablet, suspension and ointment

Answer 20

Question 21

acyclovir rx for adults (recurrent and primary infections)

adjusted for?

Answer 21

Question 22

valcyclovir preps

Answer 22

Oral: tablets (500 mg or 1000 mg)

Question 23

valcyclovir dosing (primary and recurrent infections)

adjust for?

Answer 23

Question 24

penciclovir prep

Answer 24

1% external cream

Question 25

penciclovir dosing

Answer 25

Question 26

famciclovir preps

Answer 26

Oral: tablets (125, 250, and 500 mg) *Tablets contain lactose

Question 27

famciclovir dosing (primary and recurrent infections) | adjust for?

Answer 27

Question 28

Docosanol preps

Answer 28

10% external cream

Question 29

docosanol dosing

Answer 29

Question 30

acyclovr suspensionexample rx

Answer 30

Question 31

valacyclovir recurrence example rx

Answer 31

Question 32

penciclovir example rx

Answer 32

Question 33

famciclovir recurrence example rx

Answer 33

Question 34

Oseltamivir prep | oral ans suspension

Answer 34

Question 35

Oseltamivir dosing | tx and prevention,adjust for?

Answer 35

Question 36

Baloxavir marboxil prep

Answer 36

single tablet pack (40 or 80 mg)

Question 37

Baloxavir marboxil dosage | tx and prophy

Answer 37

Question 38

oseltamavir example rx

Answer 38

Question 39

Baloxavir marboxil example rx

Answer 39

Question 40

Oropharyngeal thrush tx options

Answer 40

Question 41

fluconazole tx of esphogeal thrush

Answer 41

Fluconazole - 400 mg as a loading dose and then 200 to 400 mg daily for 14 to 21days given orally

Question 42

Miconazole (Oravig) dosage

Answer 42

50 mg (1 tablet) applied to upper gum once daily for 7-14 days * Apply in morning after brushing. Alternate sides of mouth with each application; do not crush, chew, or swallow. Avoid chewing gum while in place. * If the tablet does not adhere to gum or falls off within 6 hours of application, same tablet should be repositioned immediately. * Exposure time important: goal entirety of waking hours.

Question 43

Clotrimazole (Mycelex) dosage * Metabolized in? contraindicated in? * Avoid in combination with? * Oral Troche?

Answer 43

10mg (1 troche) dissolved slowly 5 times daily for 7-14 days * Metabolized in liver – 3A4. Contraindicated in liver disease. * Avoid in combination with benzodiazapines; HIV * Oral Troche for management of oral candidiasis

Question 44

Fluconazole (Diflucan) dentistry uses and rx

Answer 44

Esophogeal candidiasis or refractory, resistant oral candidiasis. Rx: Fluconazole 200mg tablet, #15 400mg once, then 200mg PO daily x 14days

Question 45

Clotrimazole (Mycelex) troches example rx for topical

Answer 45

Question 46

Nystatin oral suspension example rx

Answer 46

Question 47

Oravig (Miconazole) example rx

Answer 47

Question 48

Magic Mouthwash formula

Answer 48

* NO STANDARD formula * 80% of healthcare facilities compound their own unique formula

Question 49

Magic Mouthwash Ingredients * Most Common:

Answer 49

* Diphenhydramine (Benadryl) >90% * Viscous lidocaine 90% * Magnesium hydroxide/ Aluminum hydroxide (Maalox) 80% * Nystatin 30% * Corticosteroids 10% * Tetracyclines 10%