Unit 10 - Breast Cancer

Question 1

What are some risk factors for breast cancer that are not lifestyle factors?

Answer 1

Caucasians
Dense breast tissue
Early puberty
Chest Radiation

Question 2

What are some risk factors for breast cancer that are lifestyle factors?

Answer 2

Lack of breastfeeding
Hormone Therapy
Alcohol Consumption
Obesity

Question 3

What are the BRCA 1 and BRCA 2 genes?

Answer 3

Tumor supressor genes.

They Repair DNA damage, and get rid of damaged DNA.

Question 4

How does breast cancer actually happen?

Answer 4

Interaction between environmental factor and genetic susceptibility.

Question 5

What are hormonally sensitive tests for breast cancer?

Answer 5

Estrogen Receptor ER
Progesterone Receptor ER
Epidermal Growth Receptor HER

Question 6

Clinical Manifestations for Breast Cancer?

Answer 6

Lump
Skin Dimpling
Change in skin
Change in Nipple
Leakage out of nipple

Question 7

Basic Cancer Timeline (Breast Cancer)

Answer 7

DNA Damaging agent
DNA damaged
Failed repair
Mutations in genome
Protoncogenes activated
Cell proliferation
Angiogenesis
Malignant
Invasion and Metastasis